Source: CLINVAR

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1057519733
rs1057519733
MAP2K1
CUI: C0025202
Disease: melanoma
melanoma 		A 0.700 CausalMutation CLINVAR Pharmacodynamic effects and mechanisms of resistance to vemurafenib in patients with metastatic melanoma. 23569304

2013
dbSNP: rs1057519733
rs1057519733
MAP2K1
CUI: C0025202
Disease: melanoma
melanoma 		A 0.700 CausalMutation CLINVAR Exome sequencing identifies recurrent somatic MAP2K1 and MAP2K2 mutations in melanoma. 22197931

2011
dbSNP: rs1057519733
rs1057519733
MAP2K1
CUI: C0025202
Disease: melanoma
melanoma 		A 0.700 CausalMutation CLINVAR MEK1 mutations confer resistance to MEK and B-RAF inhibition. 19915144

2009