Source: CURATED

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs8034191
rs8034191
HYKK
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		0.800 GeneticVariation GWASCAT A meta-analysis provided increased support that variation at 15q25.1 (rs8034191; P = 3.24 x 10(-26)), 5p15.33 (rs4975616; P = 2.99 x 10(-9)), and 6p21.33 (rs3117582; P = 4.46 x 10(-10)) influences lung cancer risk. 19654303

2009
dbSNP: rs8034191
rs8034191
HYKK
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		G 0.800 GeneticVariation GWASCAT Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1. 18385676

2008
dbSNP: rs8034191
rs8034191
HYKK
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		C 0.800 GeneticVariation GWASCAT A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25. 18385738

2008
dbSNP: rs8034191
rs8034191
HYKK
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		G 0.800 GeneticVariation GWASCAT The risk of lung cancer was more than fivefold higher among those subjects who had both a family history of lung cancer and two copies of high-risk alleles rs8034191 (odds ratio [OR] = 7.20, 95% confidence interval [CI] = 2.21 to 23.37) or rs1051730 (OR = 5.67, CI = 2.21 to 14.60, both of which were located in the 15q24-25.1 locus, than among control subjects. 18780872

2008