Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs34637584
rs34637584
CUI: C1846862
Disease: PARKINSON DISEASE 8 (disorder)
PARKINSON DISEASE 8 (disorder)
0.810 GeneticVariation UNIPROT EFNS/MDS-ES/ENS [corrected] recommendations for the diagnosis of Parkinson's disease. 23279440

2013

dbSNP: rs33939927
rs33939927
CUI: C1846862
Disease: PARKINSON DISEASE 8 (disorder)
PARKINSON DISEASE 8 (disorder)
0.800 GeneticVariation UNIPROT Rab29 activation of the Parkinson's disease-associated LRRK2 kinase. 29212815

2018

dbSNP: rs33939927
rs33939927
CUI: C1846862
Disease: PARKINSON DISEASE 8 (disorder)
PARKINSON DISEASE 8 (disorder)
0.800 GeneticVariation UNIPROT Structural interface between LRRK2 and 14-3-3 protein. 28202711

2017

dbSNP: rs33939927
rs33939927
CUI: C1846862
Disease: PARKINSON DISEASE 8 (disorder)
PARKINSON DISEASE 8 (disorder)
0.800 GeneticVariation UNIPROT Phosphorylation of amyloid precursor protein by mutant LRRK2 promotes AICD activity and neurotoxicity in Parkinson's disease. 28720718

2017

dbSNP: rs33939927
rs33939927
CUI: C1846862
Disease: PARKINSON DISEASE 8 (disorder)
PARKINSON DISEASE 8 (disorder)
0.800 GeneticVariation UNIPROT Phosphoproteomics reveals that Parkinson's disease kinase LRRK2 regulates a subset of Rab GTPases. 26824392

2016

dbSNP: rs33939927
rs33939927
CUI: C1846862
Disease: PARKINSON DISEASE 8 (disorder)
PARKINSON DISEASE 8 (disorder)
0.800 GeneticVariation UNIPROT EFNS/MDS-ES/ENS [corrected] recommendations for the diagnosis of Parkinson's disease. 23279440

2013

dbSNP: rs33939927
rs33939927
CUI: C1846862
Disease: PARKINSON DISEASE 8 (disorder)
PARKINSON DISEASE 8 (disorder)
0.800 GeneticVariation UNIPROT Systematic review and UK-based study of PARK2 (parkin), PINK1, PARK7 (DJ-1) and LRRK2 in early-onset Parkinson's disease. 22956510

2012

dbSNP: rs33939927
rs33939927
CUI: C1846862
Disease: PARKINSON DISEASE 8 (disorder)
PARKINSON DISEASE 8 (disorder)
0.800 GeneticVariation UNIPROT LRRK2 G2019S is a common mutation in Spanish patients with late-onset Parkinson's disease. 16298482

2006

dbSNP: rs33939927
rs33939927
CUI: C1846862
Disease: PARKINSON DISEASE 8 (disorder)
PARKINSON DISEASE 8 (disorder)
0.800 GeneticVariation UNIPROT Comprehensive analysis of the LRRK2 gene in sixty families with Parkinson's disease. 16333314

2006

dbSNP: rs33939927
rs33939927
CUI: C1846862
Disease: PARKINSON DISEASE 8 (disorder)
PARKINSON DISEASE 8 (disorder)
0.800 GeneticVariation UNIPROT LRRK2 mutations in Spanish patients with Parkinson disease: frequency, clinical features, and incomplete penetrance. 16533964

2006

dbSNP: rs33939927
rs33939927
CUI: C1846862
Disease: PARKINSON DISEASE 8 (disorder)
PARKINSON DISEASE 8 (disorder)
0.800 GeneticVariation UNIPROT Parkinson's disease and LRRK2: frequency of a common mutation in U.S. movement disorder clinics. 16250030

2006

dbSNP: rs33939927
rs33939927
CUI: C1846862
Disease: PARKINSON DISEASE 8 (disorder)
PARKINSON DISEASE 8 (disorder)
0.800 GeneticVariation UNIPROT Genetic and clinical identification of Parkinson's disease patients with LRRK2 G2019S mutation. 15929036

2005

dbSNP: rs33939927
rs33939927
CUI: C1846862
Disease: PARKINSON DISEASE 8 (disorder)
PARKINSON DISEASE 8 (disorder)
0.800 GeneticVariation UNIPROT Clinical and positron emission tomography of Parkinson's disease caused by LRRK2. 15732108

2005

dbSNP: rs33939927
rs33939927
CUI: C1846862
Disease: PARKINSON DISEASE 8 (disorder)
PARKINSON DISEASE 8 (disorder)
0.800 GeneticVariation UNIPROT The G6055A (G2019S) mutation in LRRK2 is frequent in both early and late onset Parkinson's disease and originates from a common ancestor. 16272257

2005

dbSNP: rs33939927
rs33939927
CUI: C1846862
Disease: PARKINSON DISEASE 8 (disorder)
PARKINSON DISEASE 8 (disorder)
0.800 GeneticVariation UNIPROT Genetic screening for a single common LRRK2 mutation in familial Parkinson's disease. 15680455

2005

dbSNP: rs33939927
rs33939927
CUI: C1846862
Disease: PARKINSON DISEASE 8 (disorder)
PARKINSON DISEASE 8 (disorder)
0.800 GeneticVariation UNIPROT A common LRRK2 mutation in idiopathic Parkinson's disease. 15680457

2005

dbSNP: rs33939927
rs33939927
CUI: C1846862
Disease: PARKINSON DISEASE 8 (disorder)
PARKINSON DISEASE 8 (disorder)
0.800 GeneticVariation UNIPROT LRRK2 mutations in Parkinson disease. 16157908

2005

dbSNP: rs33939927
rs33939927
CUI: C1846862
Disease: PARKINSON DISEASE 8 (disorder)
PARKINSON DISEASE 8 (disorder)
0.800 GeneticVariation UNIPROT Type and frequency of mutations in the LRRK2 gene in familial and sporadic Parkinson's disease*. 16251215

2005

dbSNP: rs33939927
rs33939927
CUI: C1846862
Disease: PARKINSON DISEASE 8 (disorder)
PARKINSON DISEASE 8 (disorder)
0.800 GeneticVariation UNIPROT Clinical features of LRRK2-associated Parkinson's disease in central Norway. 15852371

2005

dbSNP: rs33939927
rs33939927
CUI: C1846862
Disease: PARKINSON DISEASE 8 (disorder)
PARKINSON DISEASE 8 (disorder)
0.800 GeneticVariation UNIPROT G2019S LRRK2 mutation in French and North African families with Parkinson's disease. 16240353

2005

dbSNP: rs33939927
rs33939927
CUI: C1846862
Disease: PARKINSON DISEASE 8 (disorder)
PARKINSON DISEASE 8 (disorder)
0.800 GeneticVariation UNIPROT Identification of a novel LRRK2 mutation linked to autosomal dominant parkinsonism: evidence of a common founder across European populations. 15726496

2005

dbSNP: rs33939927
rs33939927
CUI: C1846862
Disease: PARKINSON DISEASE 8 (disorder)
PARKINSON DISEASE 8 (disorder)
0.800 GeneticVariation UNIPROT Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology. 15541309

2004

dbSNP: rs34805604
rs34805604
CUI: C1846862
Disease: PARKINSON DISEASE 8 (disorder)
PARKINSON DISEASE 8 (disorder)
0.800 GeneticVariation UNIPROT Rab29 activation of the Parkinson's disease-associated LRRK2 kinase. 29212815

2018

dbSNP: rs34805604
rs34805604
CUI: C1846862
Disease: PARKINSON DISEASE 8 (disorder)
PARKINSON DISEASE 8 (disorder)
0.800 GeneticVariation UNIPROT Structural interface between LRRK2 and 14-3-3 protein. 28202711

2017

dbSNP: rs34805604
rs34805604
CUI: C1846862
Disease: PARKINSON DISEASE 8 (disorder)
PARKINSON DISEASE 8 (disorder)
0.800 GeneticVariation UNIPROT Phosphorylation of amyloid precursor protein by mutant LRRK2 promotes AICD activity and neurotoxicity in Parkinson's disease. 28720718

2017