Source: BEFREE ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3952
Gene Symbol: LEP
LEP 		P41159 leptin 807 0.349 0.846 0.46 0.240 None 1.000 4 0 2002 2019
Entrez Id: 5265
Gene Symbol: SERPINA1
SERPINA1 		P01009 serpin family A member 1 Enzyme modulator 411 0.410 0.923 6.8E-08 0.220 None 1.000 2 0 2015 2019
Entrez Id: 5068
Gene Symbol: REG3A
REG3A 		Q06141 regenerating family member 3 alpha 143 0.522 0.769 6.3E-04 0.210 None 1.000 1 0 1996 2008
Entrez Id: 348
Gene Symbol: APOE
APOE 		P02649 apolipoprotein E 886 0.338 0.962 1.9E-03 0.130 None 1.000 3 0 1994 2013
Entrez Id: 3569
Gene Symbol: IL6
IL6 		P05231 interleukin 6 2132 0.248 0.962 0.32 0.100 None 0.949 39 2 2000 2020
Entrez Id: 7124
Gene Symbol: TNF
TNF 		P01375 tumor necrosis factor Signaling 2475 0.231 0.962 0.80 0.100 None 0.946 37 1 1998 2019
Entrez Id: 1401
Gene Symbol: CRP
CRP 		P02741 C-reactive protein 1410 0.299 0.962 3.7E-03 0.100 None 1.000 26 0 2017 2019
Entrez Id: 4353
Gene Symbol: MPO
MPO 		P05164 myeloperoxidase Enzyme 584 0.377 0.923 7.1E-15 0.100 None 1.000 21 0 2008 2020
Entrez Id: 3553
Gene Symbol: IL1B
IL1B 		P01584 interleukin 1 beta 1604 0.276 0.962 0.13 0.100 None 0.889 18 2 1998 2019
Entrez Id: 3586
Gene Symbol: IL10
IL10 		P22301 interleukin 10 1533 0.281 0.923 5.9E-03 0.100 None 0.733 15 3 1998 2020
Entrez Id: 6690
Gene Symbol: SPINK1
SPINK1 		P00995 serine peptidase inhibitor Kazal type 1 179 0.492 0.808 0.31 0.100 None 0.929 14 1 2004 2019
Entrez Id: 5644
Gene Symbol: PRSS1
PRSS1 		P07477 serine protease 1 Enzyme 79 0.563 0.692 4.1E-11 0.100 None 0.923 13 6 1997 2020
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3 		Q96P20 NLR family pyrin domain containing 3 702 0.361 0.962 8.1E-04 0.100 None 1.000 12 0 2017 2020
Entrez Id: 3146
Gene Symbol: HMGB1
HMGB1 		P09429 high mobility group box 1 Nucleic acid binding 671 0.368 0.923 0.82 0.100 None 1.000 12 0 2009 2018
Entrez Id: 1080
Gene Symbol: CFTR
CFTR 		P13569 CF transmembrane conductance regulator Ion channel 365 0.424 0.885 2.2E-58 0.100 None 1.000 11 2 2002 2019
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8 		P10145 C-X-C motif chemokine ligand 8 Signaling 1173 0.310 0.962 2.7E-04 0.100 None 0.909 11 1 2006 2020
Entrez Id: 284697
Gene Symbol: BTBD8
BTBD8 		Q5XKL5 BTB domain containing 8 123 0.547 0.692 6.1E-07 0.100 None 1.000 10 0 2005 2019
Entrez Id: 7099
Gene Symbol: TLR4
TLR4 		O00206 toll like receptor 4 1030 0.321 0.962 4.6E-09 0.100 None 0.900 10 2 2006 2018
Entrez Id: 1803
Gene Symbol: DPP4
DPP4 		P27487 dipeptidyl peptidase 4 Enzyme 436 0.420 0.808 7.3E-09 0.090 None 1.000 9 0 2017 2020
Entrez Id: 5645
Gene Symbol: PRSS2
PRSS2 		P07478 serine protease 2 Enzyme 45 0.628 0.769 0.070 None 0.857 7 4 2017 2020
Entrez Id: 6347
Gene Symbol: CCL2
CCL2 		P13500 C-C motif chemokine ligand 2 Signaling 994 0.321 0.962 0.61 0.070 None 1.000 7 0 2005 2019
Entrez Id: 6774
Gene Symbol: STAT3
STAT3 		P40763 signal transducer and activator of transcription 3 Nucleic acid binding 999 0.320 0.923 1.00 0.070 None 1.000 7 0 2011 2020
Entrez Id: 1432
Gene Symbol: MAPK14
MAPK14 		Q16539 mitogen-activated protein kinase 14 Kinase 594 0.379 0.923 0.37 0.070 None 1.000 7 0 2018 2019
Entrez Id: 213
Gene Symbol: ALB
ALB 		P02768 albumin Transporter 1089 0.317 0.962 0.64 0.070 None 1.000 7 0 2017 2019
Entrez Id: 2551
Gene Symbol: GABPA
GABPA 		Q06546 GA binding protein transcription factor subunit alpha Transcription factor 630 0.379 0.885 1.00 0.060 None 0.833 6 0 2018 2019