Source: BEFREE ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 2245 0.236 0.962 0.53 0.700 None 0.975 351 8 1986 2020
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1043 0.314 0.962 1.00 0.600 None 0.965 63 1 1996 2019
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		P00533 epidermal growth factor receptor Kinase 1308 0.295 0.885 0.37 0.400 None 0.971 704 13 1988 2020
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		P01116 KRAS proto-oncogene, GTPase Enzyme modulator 805 0.320 0.923 7.9E-04 0.400 None 0.948 313 4 1983 2020
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		P04626 erb-b2 receptor tyrosine kinase 2 Kinase 942 0.328 0.923 6.0E-03 0.400 None 0.973 243 3 1986 2020
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		P42771 Q8N726 cyclin dependent kinase inhibitor 2A 1214 0.300 0.885 0.39 0.400 None 0.941 109 1 1995 2020
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		P35222 catenin beta 1 1156 0.303 0.885 1.00 0.400 None 0.969 57 0 1997 2019
Entrez Id: 324
Gene Symbol: APC
APC 		P25054 APC regulator of WNT signaling pathway 517 0.373 0.962 1.00 0.400 None 0.982 53 1 1992 2019
Entrez Id: 4233
Gene Symbol: MET
MET 		P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 501 0.380 0.846 0.97 0.400 None 0.947 48 1 1993 2019
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		P60484 phosphatase and tensin homolog Enzyme 983 0.305 0.923 0.26 0.400 None 0.980 44 0 1995 2019
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		P15692 vascular endothelial growth factor A Signaling 1737 0.266 0.923 2.4E-05 0.400 None 0.943 43 2 1996 2019
Entrez Id: 596
Gene Symbol: BCL2
BCL2 		P10415 BCL2 apoptosis regulator Signaling 1294 0.291 0.885 0.56 0.400 None 0.911 40 1 1993 2019
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1277 0.292 0.923 1.00 0.400 None 1.000 39 0 2002 2019
Entrez Id: 8626
Gene Symbol: TP63
TP63 		Q9H3D4 tumor protein p63 Transcription factor 553 0.362 0.769 1.00 0.400 None 0.919 33 3 2001 2020
Entrez Id: 2099
Gene Symbol: ESR1
ESR1 		P03372 estrogen receptor 1 Nuclear receptor 972 0.324 0.962 1.00 0.400 None 0.914 32 1 1991 2020
Entrez Id: 595
Gene Symbol: CCND1
CCND1 		P24385 cyclin D1 Enzyme modulator 748 0.344 0.923 0.89 0.400 None 1.000 28 0 1990 2019
Entrez Id: 1950
Gene Symbol: EGF
EGF 		P01133 epidermal growth factor 717 0.357 0.923 8.5E-17 0.400 None 0.966 27 0 1986 2018
Entrez Id: 11186
Gene Symbol: RASSF1
RASSF1 		Q9NS23 Ras association domain family member 1 Enzyme modulator 378 0.420 0.808 4.9E-06 0.400 None 0.962 24 0 2001 2018
Entrez Id: 4609
Gene Symbol: MYC
MYC 		P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 747 0.344 0.923 1.00 0.400 None 1.000 23 0 1988 2018
Entrez Id: 6794
Gene Symbol: STK11
STK11 		Q15831 serine/threonine kinase 11 Kinase 303 0.435 0.808 0.99 0.400 None 0.962 22 0 1998 2019
Entrez Id: 4583
Gene Symbol: MUC2
MUC2 		Q02817 mucin 2, oligomeric mucus/gel-forming Enzyme modulator 195 0.486 0.808 9.4E-10 0.400 None 1.000 21 0 1994 2019
Entrez Id: 54474
Gene Symbol: KRT20
KRT20 		P35900 keratin 20 545 0.388 0.846 9.1E-11 0.400 None 0.870 21 0 1993 2020
Entrez Id: 2520
Gene Symbol: GAST
GAST 		P01350 gastrin 219 0.485 0.808 2.7E-03 0.400 None 1.000 15 0 1986 2018
Entrez Id: 6774
Gene Symbol: STAT3
STAT3 		P40763 signal transducer and activator of transcription 3 Nucleic acid binding 999 0.320 0.923 1.00 0.400 None 1.000 15 0 2002 2018
Entrez Id: 7124
Gene Symbol: TNF
TNF 		P01375 tumor necrosis factor Signaling 2475 0.231 0.962 0.80 0.400 None 1.000 15 1 1991 2017