|
| Entrez Id: |
351 |
| Gene Symbol: |
APP |
APP
|
P05067
|
amyloid beta precursor protein
|
Enzyme modulator
|
76
|
0.422 |
0.846 |
4.7E-02 |
0.900 |
None
|
0.981 |
63
|
14
|
1987 |
2020 |
|
| Entrez Id: |
1636 |
| Gene Symbol: |
ACE |
ACE
|
P12821
|
angiotensin I converting enzyme
|
Enzyme
|
101
|
0.328 |
0.923 |
1.0E-37 |
0.900 |
strong
|
0.915 |
5
|
1
|
1998 |
2020 |
|
| Entrez Id: |
5663 |
| Gene Symbol: |
PSEN1 |
PSEN1
|
P49768
|
presenilin 1
|
Enzyme
|
45
|
0.469 |
0.846 |
0.97 |
0.700 |
None
|
0.971 |
13
|
6
|
1990 |
2020 |
|
| Entrez Id: |
348 |
| Gene Symbol: |
APOE |
APOE
|
P02649
|
apolipoprotein E
|
|
115
|
0.338 |
0.962 |
1.9E-03 |
0.700 |
None
|
0.946 |
9
|
10
|
1991 |
2020 |
|
| Entrez Id: |
4137 |
| Gene Symbol: |
MAPT |
MAPT
|
P10636
|
microtubule associated protein tau
|
|
66
|
0.446 |
0.923 |
6.0E-03 |
0.700 |
None
|
0.990 |
7
|
1
|
1988 |
2020 |
|
| Entrez Id: |
54209 |
| Gene Symbol: |
TREM2 |
TREM2
|
Q9NZC2
|
triggering receptor expressed on myeloid cells 2
|
|
19
|
0.519 |
0.769 |
3.3E-09 |
0.700 |
limited
|
0.977 |
3
|
2
|
2007 |
2020 |
|
| Entrez Id: |
3077 |
| Gene Symbol: |
HFE |
HFE
|
Q30201
|
homeostatic iron regulator
|
|
26
|
0.436 |
0.846 |
2.6E-08 |
0.700 |
strong
|
0.963 |
2
|
1
|
2001 |
2018 |
|
| Entrez Id: |
2932 |
| Gene Symbol: |
GSK3B |
GSK3B
|
P49841
|
glycogen synthase kinase 3 beta
|
Kinase
|
51
|
0.430 |
0.846 |
0.96 |
0.700 |
None
|
0.982 |
2
|
1
|
2000 |
2020 |
|
| Entrez Id: |
102 |
| Gene Symbol: |
ADAM10 |
ADAM10
|
O14672
|
ADAM metallopeptidase domain 10
|
|
17
|
0.489 |
0.846 |
1.00 |
0.700 |
None
|
0.986 |
1
|
1
|
2000 |
2019 |
|
| Entrez Id: |
5328 |
| Gene Symbol: |
PLAU |
PLAU
|
P00749
|
plasminogen activator, urokinase
|
Enzyme
|
109
|
0.425 |
0.923 |
2.3E-06 |
0.680 |
None
|
1.000 |
0
|
0
|
2002 |
2013 |
|
| Entrez Id: |
3553 |
| Gene Symbol: |
IL1B |
IL1B
|
P01584
|
interleukin 1 beta
|
|
231
|
0.276 |
0.962 |
0.13 |
0.600 |
None
|
0.966 |
1
|
0
|
1989 |
2020 |
|
| Entrez Id: |
3416 |
| Gene Symbol: |
IDE |
IDE
|
P14735
|
insulin degrading enzyme
|
Enzyme
|
8
|
0.604 |
0.577 |
6.6E-03 |
0.600 |
None
|
0.955 |
1
|
0
|
2000 |
2019 |
|
| Entrez Id: |
3952 |
| Gene Symbol: |
LEP |
LEP
|
P41159
|
leptin
|
|
114
|
0.349 |
0.846 |
0.46 |
0.600 |
None
|
0.944 |
1
|
0
|
2004 |
2019 |
|
| Entrez Id: |
4852 |
| Gene Symbol: |
NPY |
NPY
|
P01303
|
neuropeptide Y
|
Signaling
|
109
|
0.447 |
0.846 |
0.14 |
0.600 |
None
|
0.833 |
1
|
0
|
2000 |
2018 |
|
| Entrez Id: |
627 |
| Gene Symbol: |
BDNF |
BDNF
|
P23560
|
brain derived neurotrophic factor
|
Signaling
|
119
|
0.345 |
0.923 |
0.66 |
0.600 |
None
|
0.958 |
1
|
0
|
1991 |
2020 |
|
| Entrez Id: |
596 |
| Gene Symbol: |
BCL2 |
BCL2
|
P10415
|
BCL2 apoptosis regulator
|
Signaling
|
141
|
0.291 |
0.885 |
0.56 |
0.600 |
None
|
1.000 |
1
|
0
|
1996 |
2019 |
|
| Entrez Id: |
3643 |
| Gene Symbol: |
INSR |
INSR
|
P06213
|
insulin receptor
|
Kinase
|
60
|
0.432 |
0.846 |
3.6E-05 |
0.600 |
None
|
1.000 |
1
|
0
|
2002 |
2020 |
|
| Entrez Id: |
23621 |
| Gene Symbol: |
BACE1 |
BACE1
|
P56817
|
beta-secretase 1
|
Enzyme
|
8
|
0.559 |
0.769 |
0.88 |
0.600 |
None
|
0.985 |
1
|
0
|
1999 |
2020 |
|
| Entrez Id: |
836 |
| Gene Symbol: |
CASP3 |
CASP3
|
P42574
|
caspase 3
|
Enzyme
|
72
|
0.351 |
0.923 |
0.10 |
0.600 |
None
|
0.980 |
1
|
0
|
1999 |
2020 |
|
| Entrez Id: |
3481 |
| Gene Symbol: |
IGF2 |
IGF2
|
P01344
|
insulin like growth factor 2
|
|
59
|
0.390 |
0.885 |
4.4E-02 |
0.570 |
None
|
1.000 |
1
|
0
|
2002 |
2019 |
|
| Entrez Id: |
3480 |
| Gene Symbol: |
IGF1R |
IGF1R
|
P08069
|
insulin like growth factor 1 receptor
|
Kinase
|
44
|
0.399 |
0.885 |
0.97 |
0.560 |
None
|
1.000 |
1
|
0
|
2005 |
2020 |
|
| Entrez Id: |
498 |
| Gene Symbol: |
ATP5F1A |
ATP5F1A
|
P25705
|
ATP synthase F1 subunit alpha
|
Transporter
|
11
|
0.604 |
0.731 |
1.00 |
0.540 |
None
|
1.000 |
1
|
0
|
2003 |
2017 |
|
| Entrez Id: |
3630 |
| Gene Symbol: |
INS |
INS
|
P01308
|
insulin
|
|
157
|
0.445 |
0.923 |
0.30 |
0.530 |
None
|
1.000 |
2
|
0
|
1991 |
2020 |
|
| Entrez Id: |
581 |
| Gene Symbol: |
BAX |
BAX
|
Q07812
|
BCL2 associated X, apoptosis regulator
|
Signaling
|
51
|
0.417 |
0.885 |
0.32 |
0.520 |
None
|
1.000 |
1
|
0
|
1997 |
2018 |
|
| Entrez Id: |
6653 |
| Gene Symbol: |
SORL1 |
SORL1
|
Q92673
|
sortilin related receptor 1
|
Transporter
|
19
|
0.582 |
0.692 |
7.7E-11 |
0.500 |
None
|
0.973 |
4
|
4
|
2004 |
2020 |