Source: CURATED ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22 		Q9Y2R2 protein tyrosine phosphatase non-receptor type 22 17 0.438 0.846 3.5E-21 0.700 None 0.899 6 4 2004 2019
Entrez Id: 7124
Gene Symbol: TNF
TNF 		P01375 tumor necrosis factor Signaling 340 0.231 0.962 0.80 0.700 None 0.975 4 2 1989 2020
Entrez Id: 6583
Gene Symbol: SLC22A4
SLC22A4 		Q9H015 solute carrier family 22 member 4 Transporter 6 0.603 0.769 1.8E-08 0.700 None 0.857 1 0 2003 2019
Entrez Id: 1401
Gene Symbol: CRP
CRP 		P02741 C-reactive protein 80 0.299 0.962 3.7E-03 0.600 None 0.955 1 0 1989 2020
Entrez Id: 3572
Gene Symbol: IL6ST
IL6ST 		P40189 interleukin 6 signal transducer Signaling 36 0.475 0.808 1.00 0.590 None 0.909 1 0 2000 2020
Entrez Id: 7128
Gene Symbol: TNFAIP3
TNFAIP3 		P21580 TNF alpha induced protein 3 Enzyme 28 0.481 0.808 1.00 0.500 None 1.000 5 3 2007 2018
Entrez Id: 958
Gene Symbol: CD40
CD40 		P25942 CD40 molecule 29 0.396 0.846 0.85 0.500 None 0.848 3 3 2002 2019
Entrez Id: 1235
Gene Symbol: CCR6
CCR6 		P51684 C-C motif chemokine receptor 6 G-protein coupled receptor 13 0.485 0.808 5.8E-03 0.500 None 1.000 3 8 2001 2019
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1 		P01911 major histocompatibility complex, class II, DR beta 1 Immune response 68 0.333 0.923 1.1E-03 0.500 None 0.936 3 4 1989 2020
Entrez Id: 940
Gene Symbol: CD28
CD28 		P10747 CD28 molecule 13 0.436 0.885 0.36 0.500 None 1.000 3 1 1996 2018
Entrez Id: 3559
Gene Symbol: IL2RA
IL2RA 		P01589 interleukin 2 receptor subunit alpha Receptor 31 0.389 0.885 5.5E-02 0.500 None 1.000 3 2 1992 2019
Entrez Id: 2212
Gene Symbol: FCGR2A
FCGR2A 		P12318 Fc fragment of IgG receptor IIa Cell adhesion 14 0.480 0.769 2.0E-06 0.500 None 0.852 2 1 2002 2020
Entrez Id: 3663
Gene Symbol: IRF5
IRF5 		Q13568 interferon regulatory factor 5 Transcription factor 10 0.489 0.731 9.0E-03 0.500 None 0.906 2 4 2006 2019
Entrez Id: 6775
Gene Symbol: STAT4
STAT4 		Q14765 signal transducer and activator of transcription 4 Nucleic acid binding 17 0.471 0.769 0.77 0.500 None 0.889 2 9 2000 2019
Entrez Id: 3115
Gene Symbol: HLA-DPB1
HLA-DPB1 		P04440 major histocompatibility complex, class II, DP beta 1 Immune response 30 0.453 0.923 5.3E-10 0.500 None 0.938 2 62 1988 2020
Entrez Id: 7185
Gene Symbol: TRAF1
TRAF1 		Q13077 TNF receptor associated factor 1 Signaling 9 0.554 0.731 3.6E-03 0.500 None 0.850 2 2 2007 2019
Entrez Id: 7189
Gene Symbol: TRAF6
TRAF6 		Q9Y4K3 TNF receptor associated factor 6 Signaling 4 0.472 0.808 1.00 0.500 None 1.000 2 1 2008 2019
Entrez Id: 3570
Gene Symbol: IL6R
IL6R 		P08887 interleukin 6 receptor Signaling 21 0.471 0.846 3.2E-05 0.500 None 0.971 2 2 2001 2019
Entrez Id: 23569
Gene Symbol: PADI4
PADI4 		Q9UM07 peptidyl arginine deiminase 4 9 0.494 0.808 4.6E-16 0.500 None 0.912 1 7 2003 2020
Entrez Id: 3586
Gene Symbol: IL10
IL10 		P22301 interleukin 10 95 0.281 0.923 5.9E-03 0.500 None 0.946 1 0 1994 2020
Entrez Id: 4261
Gene Symbol: CIITA
CIITA 		P33076 class II major histocompatibility complex transactivator 5 0.536 0.808 1.4E-07 0.500 None 0.533 0 1 2006 2017
Entrez Id: 7297
Gene Symbol: TYK2
TYK2 		P29597 tyrosine kinase 2 Kinase 31 0.505 0.769 4.5E-08 0.490 None 1.000 2 2 2007 2019
Entrez Id: 861
Gene Symbol: RUNX1
RUNX1 		Q01196 RUNX family transcription factor 1 Transcription factor 21 0.425 0.808 0.65 0.490 None 0.786 1 2 2003 2019
Entrez Id: 5771
Gene Symbol: PTPN2
PTPN2 		P17706 protein tyrosine phosphatase non-receptor type 2 10 0.538 0.692 1.00 0.490 None 1.000 1 3 2012 2019
Entrez Id: 5788
Gene Symbol: PTPRC
PTPRC 		P08575 protein tyrosine phosphatase receptor type C Enzyme 15 0.435 0.808 1.00 0.480 None 1.000 2 1 1991 2017