Source: BEFREE ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 472
Gene Symbol: ATM
ATM 		Q13315 ATM serine/threonine kinase Kinase 563 0.374 0.885 5.6E-47 1.000 None 0.982 417 9 1953 2020
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 2245 0.236 0.962 0.53 0.100 None 0.939 49 1 1992 2019
Entrez Id: 174
Gene Symbol: AFP
AFP 		P02771 alpha fetoprotein Transporter 374 0.429 0.885 1.1E-11 0.100 None 0.944 18 0 1980 2019
Entrez Id: 1111
Gene Symbol: CHEK1
CHEK1 		O14757 checkpoint kinase 1 Kinase 189 0.492 0.808 3.1E-08 0.100 None 1.000 15 0 1999 2020
Entrez Id: 3014
Gene Symbol: H2AX
H2AX 		P16104 H2A.X variant histone Nucleic acid binding 194 0.484 0.808 0.18 0.100 None 1.000 14 0 2004 2019
Entrez Id: 4683
Gene Symbol: NBN
NBN 		O60934 nibrin Nucleic acid binding 212 0.467 0.808 2.2E-16 0.100 None 1.000 13 0 1997 2011
Entrez Id: 54840
Gene Symbol: APTX
APTX 		Q7Z2E3 aprataxin Nucleic acid binding 63 0.590 0.500 4.0E-10 0.100 None 1.000 11 0 2000 2017
Entrez Id: 545
Gene Symbol: ATR
ATR 		Q13535 ATR serine/threonine kinase Kinase 223 0.456 0.923 3.5E-09 0.100 None 1.000 11 0 1995 2018
Entrez Id: 55655
Gene Symbol: NLRP2
NLRP2 		Q9NX02 NLR family pyrin domain containing 2 154 0.515 0.731 1.4E-38 0.100 None 1.000 10 0 2002 2011
Entrez Id: 4361
Gene Symbol: MRE11
MRE11 		P49959 MRE11 homolog, double strand break repair nuclease 110 0.527 0.808 1.3E-12 0.090 None 1.000 9 0 2003 2019
Entrez Id: 23064
Gene Symbol: SETX
SETX 		Q7Z333 senataxin Enzyme 76 0.570 0.731 0.95 0.080 None 0.875 8 1 2004 2018
Entrez Id: 23650
Gene Symbol: TRIM29
TRIM29 		Q14134 tripartite motif containing 29 64 0.606 0.654 8.1E-08 0.080 None 1.000 8 0 1994 2019
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A 		P38936 cyclin dependent kinase inhibitor 1A 408 0.403 0.769 1.9E-03 0.080 None 0.875 6 0 1995 2013
Entrez Id: 2395
Gene Symbol: FXN
FXN 		Q16595 frataxin Enzyme 181 0.510 0.654 0.34 0.070 None 0.857 7 0 1989 2011
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2 		O96017 checkpoint kinase 2 Kinase 220 0.460 0.808 1.2E-24 0.070 None 1.000 7 0 2006 2019
Entrez Id: 9623
Gene Symbol: TCL1B
TCL1B 		O95988 T cell leukemia/lymphoma 1B 96 0.561 0.500 1.0E-02 0.070 None 0.857 7 0 1995 2004
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1 		P38398 BRCA1 DNA repair associated Enzyme 576 0.367 0.923 9.2E-29 0.060 None 1.000 6 0 1999 2015
Entrez Id: 8115
Gene Symbol: TCL1A
TCL1A 		P56279 T cell leukemia/lymphoma 1A 105 0.558 0.500 5.7E-10 0.060 None 0.833 6 0 1995 2004
Entrez Id: 6962
Gene Symbol: TRBV20OR9-2
TRBV20OR9-2 		T cell receptor beta variable 20/OR9-2 (non-functional) 456 0.403 0.923 0.060 None 1.000 6 0 1990 2014
Entrez Id: 7070
Gene Symbol: THY1
THY1 		P04216 Thy-1 cell surface antigen 193 0.496 0.808 5.0E-02 0.050 None 0.800 5 0 1990 2000
Entrez Id: 2120
Gene Symbol: ETV6
ETV6 		P41212 ETS variant transcription factor 6 Transcription factor 202 0.477 0.731 0.97 0.050 None 1.000 5 0 1995 2019
Entrez Id: 952
Gene Symbol: CD38
CD38 		P28907 CD38 molecule Enzyme 463 0.407 0.885 2.3E-06 0.050 None 1.000 5 0 1989 1994
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 888 0.319 0.846 1.00 0.040 None 1.000 4 2 2017 2019
Entrez Id: 5265
Gene Symbol: SERPINA1
SERPINA1 		P01009 serpin family A member 1 Enzyme modulator 411 0.410 0.923 6.8E-08 0.040 None 1.000 4 0 2014 2019
Entrez Id: 8102
Gene Symbol: XRS
XRS 		X-ray sensitivity 19 0.716 0.500 0.040 None 0.750 4 0 1989 2014