Source: BEFREE ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 4318
Gene Symbol: MMP9
MMP9 		P14780 matrix metallopeptidase 9 Enzyme 1160 0.305 0.923 1.9E-17 0.320 None 1.000 2 0 2005 2008
Entrez Id: 5328
Gene Symbol: PLAU
PLAU 		P00749 plasminogen activator, urokinase Enzyme 301 0.425 0.923 2.3E-06 0.310 None 1.000 1 0 2006 2008
Entrez Id: 4313
Gene Symbol: MMP2
MMP2 		P08253 matrix metallopeptidase 2 Enzyme 826 0.333 0.923 0.84 0.310 None 1.000 1 0 2006 2017
Entrez Id: 2130
Gene Symbol: EWSR1
EWSR1 		Q01844 EWS RNA binding protein 1 Nucleic acid binding 229 0.474 0.692 1.00 0.070 None 1.000 7 0 2005 2019
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		P00533 epidermal growth factor receptor Kinase 1308 0.295 0.885 0.37 0.040 None 1.000 4 0 2007 2018
Entrez Id: 5744
Gene Symbol: PTHLH
PTHLH 		P12272 parathyroid hormone like hormone 277 0.453 0.846 0.81 0.040 None 1.000 4 0 2002 2020
Entrez Id: 4982
Gene Symbol: TNFRSF11B
TNFRSF11B 		O00300 TNF receptor superfamily member 11b 369 0.422 0.808 0.16 0.040 None 1.000 4 0 2005 2013
Entrez Id: 3418
Gene Symbol: IDH2
IDH2 		P48735 isocitrate dehydrogenase (NADP(+)) 2 292 0.434 0.808 0.88 0.040 None 1.000 4 0 2014 2019
Entrez Id: 8792
Gene Symbol: TNFRSF11A
TNFRSF11A 		Q9Y6Q6 TNF receptor superfamily member 11a 196 0.480 0.846 8.8E-03 0.040 None 1.000 3 0 2004 2017
Entrez Id: 2099
Gene Symbol: ESR1
ESR1 		P03372 estrogen receptor 1 Nuclear receptor 972 0.324 0.962 1.00 0.030 None 0.667 3 0 2003 2019
Entrez Id: 4193
Gene Symbol: MDM2
MDM2 		Q00987 MDM2 proto-oncogene Nucleic acid binding 669 0.362 0.846 1.00 0.030 None 1.000 3 1 1998 2014
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		P04626 erb-b2 receptor tyrosine kinase 2 Kinase 942 0.328 0.923 6.0E-03 0.030 None 1.000 3 0 2008 2017
Entrez Id: 2131
Gene Symbol: EXT1
EXT1 		Q16394 exostosin glycosyltransferase 1 Enzyme 120 0.522 0.769 1.00 0.030 None 1.000 3 0 1998 2017
Entrez Id: 8600
Gene Symbol: TNFSF11
TNFSF11 		O14788 TNF superfamily member 11 Signaling 253 0.453 0.846 4.9E-03 0.030 None 1.000 3 0 2014 2018
Entrez Id: 860
Gene Symbol: RUNX2
RUNX2 		Q13950 RUNX family transcription factor 2 Transcription factor 287 0.437 0.846 0.95 0.030 None 0.667 3 0 2011 2019
Entrez Id: 2353
Gene Symbol: FOS
FOS 		P01100 Fos proto-oncogene, AP-1 transcription factor subunit Transcription factor 361 0.411 0.885 0.26 0.030 None 1.000 3 0 2018 2020
Entrez Id: 9098
Gene Symbol: USP6
USP6 		P35125 ubiquitin specific peptidase 6 Enzyme 55 0.633 0.692 2.9E-35 0.030 None 1.000 3 0 2008 2019
Entrez Id: 3569
Gene Symbol: IL6
IL6 		P05231 interleukin 6 2132 0.248 0.962 0.32 0.030 None 0.667 3 0 2011 2019
Entrez Id: 3111
Gene Symbol: HLA-DOA
HLA-DOA 		P06340 major histocompatibility complex, class II, DO alpha Immune response 154 0.509 0.808 3.0E-10 0.020 None 1.000 2 0 2013 2016
Entrez Id: 4321
Gene Symbol: MMP12
MMP12 		P39900 matrix metallopeptidase 12 Enzyme 197 0.484 0.885 0.020 None 1.000 2 0 2001 2008
Entrez Id: 4233
Gene Symbol: MET
MET 		P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 501 0.380 0.846 0.97 0.020 None 1.000 2 0 1995 2000
Entrez Id: 6899
Gene Symbol: TBX1
TBX1 		O43435 T-box transcription factor 1 Transcription factor 225 0.433 0.808 0.84 0.020 None 1.000 2 0 2009 2013
Entrez Id: 6760
Gene Symbol: SS18
SS18 		Q15532 SS18 subunit of BAF chromatin remodeling complex Nucleic acid binding 55 0.641 0.462 0.75 0.020 None 1.000 2 0 1998 2019
Entrez Id: 3417
Gene Symbol: IDH1
IDH1 		O75874 isocitrate dehydrogenase (NADP(+)) 1 348 0.424 0.808 2.6E-12 0.020 None 1.000 2 0 2018 2019
Entrez Id: 2354
Gene Symbol: FOSB
FOSB 		P53539 FosB proto-oncogene, AP-1 transcription factor subunit Transcription factor 258 0.463 0.846 0.98 0.020 None 1.000 2 0 2017 2020