Source: BEFREE ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1080
Gene Symbol: CFTR
CFTR 		P13569 CF transmembrane conductance regulator Ion channel 365 0.424 0.885 2.2E-58 0.500 strong 0.952 21 1 1995 2019
Entrez Id: 5265
Gene Symbol: SERPINA1
SERPINA1 		P01009 serpin family A member 1 Enzyme modulator 411 0.410 0.923 6.8E-08 0.480 None 0.778 8 1 1995 2019
Entrez Id: 1767
Gene Symbol: DNAH5
DNAH5 		Q8TE73 dynein axonemal heavy chain 5 Enzyme 39 0.590 0.692 4.9E-64 0.410 strong 1.000 1 0 2019 2019
Entrez Id: 27019
Gene Symbol: DNAI1
DNAI1 		Q9UI46 dynein axonemal intermediate chain 1 Cellular structure 38 0.597 0.692 2.4E-08 0.410 None 1.000 1 0 2008 2019
Entrez Id: 8701
Gene Symbol: DNAH11
DNAH11 		Q96DT5 dynein axonemal heavy chain 11 Enzyme 17 0.587 0.692 2.5E-58 0.410 strong 1.000 1 0 2012 2012
Entrez Id: 7124
Gene Symbol: TNF
TNF 		P01375 tumor necrosis factor Signaling 2475 0.231 0.962 0.80 0.320 None 1.000 2 0 2000 2008
Entrez Id: 6772
Gene Symbol: STAT1
STAT1 		P42224 signal transducer and activator of transcription 1 Nucleic acid binding 452 0.399 0.885 1.00 0.130 None 1.000 3 0 2017 2019
Entrez Id: 6891
Gene Symbol: TAP2
TAP2 		Q03519 transporter 2, ATP binding cassette subfamily B member Transporter 129 0.517 0.808 6.9E-11 0.130 None 1.000 2 0 1995 2011
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1 		P01137 transforming growth factor beta 1 Signaling 1334 0.287 0.962 3.7E-02 0.120 None 1.000 2 0 2003 2013
Entrez Id: 6890
Gene Symbol: TAP1
TAP1 		Q03518 transporter 1, ATP binding cassette subfamily B member Transporter 162 0.500 0.808 5.3E-06 0.120 None 1.000 1 0 2007 2011
Entrez Id: 9138
Gene Symbol: ARHGEF1
ARHGEF1 		Q92888 Rho guanine nucleotide exchange factor 1 51 0.623 0.538 0.77 0.110 None 1.000 1 0 2019 2019
Entrez Id: 352909
Gene Symbol: DNAAF3
DNAAF3 		Q8N9W5 dynein axonemal assembly factor 3 36 0.599 0.731 5.5E-08 0.110 None 1.000 1 0 2019 2019
Entrez Id: 23495
Gene Symbol: TNFRSF13B
TNFRSF13B 		O14836 TNF receptor superfamily member 13B 89 0.558 0.769 2.1E-15 0.110 None 1.000 1 0 2014 2014
Entrez Id: 727897
Gene Symbol: MUC5B
MUC5B 		Q9HC84 mucin 5B, oligomeric mucus/gel-forming 114 0.532 0.808 1.00 0.110 None 1.000 1 0 2020 2020
Entrez Id: 260431
Gene Symbol: COPD
COPD 		Pulmonary disease, chronic obstructive, severe early-onset 349 0.456 0.885 0.100 None 0.967 30 0 1999 2020
Entrez Id: 4153
Gene Symbol: MBL2
MBL2 		P11226 mannose binding lectin 2 Receptor 542 0.390 0.846 2.7E-03 0.060 None 0.500 6 0 2005 2019
Entrez Id: 1991
Gene Symbol: ELANE
ELANE 		P08246 elastase, neutrophil expressed Enzyme 290 0.447 0.846 1.2E-03 0.050 None 1.000 5 0 2017 2019
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8 		P10145 C-X-C motif chemokine ligand 8 Signaling 1173 0.310 0.962 2.7E-04 0.050 None 1.000 5 0 2003 2019
Entrez Id: 4353
Gene Symbol: MPO
MPO 		P05164 myeloperoxidase Enzyme 584 0.377 0.923 7.1E-15 0.040 None 1.000 4 0 2017 2018
Entrez Id: 3605
Gene Symbol: IL17A
IL17A 		Q16552 interleukin 17A 1034 0.324 0.923 4.3E-02 0.030 None 1.000 3 0 2015 2019
Entrez Id: 2346
Gene Symbol: FOLH1
FOLH1 		Q04609 folate hydrolase 1 Enzyme 304 0.453 0.885 6.2E-09 0.020 None 1.000 2 0 2017 2018
Entrez Id: 50863
Gene Symbol: NTM
NTM 		Q9P121 neurotrimin 41 0.644 0.577 5.8E-02 0.020 None 1.000 2 0 2017 2018
Entrez Id: 3569
Gene Symbol: IL6
IL6 		P05231 interleukin 6 2132 0.248 0.962 0.32 0.020 None 1.000 2 0 2018 2019
Entrez Id: 4318
Gene Symbol: MMP9
MMP9 		P14780 matrix metallopeptidase 9 Enzyme 1160 0.305 0.923 1.9E-17 0.020 None 1.000 2 0 2003 2009
Entrez Id: 1401
Gene Symbol: CRP
CRP 		P02741 C-reactive protein 1410 0.299 0.962 3.7E-03 0.020 None 1.000 2 0 2017 2018