Source: CURATED ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7124
Gene Symbol: TNF
TNF 		P01375 tumor necrosis factor Signaling 340 0.231 0.962 0.80 0.400 None 1.000 2 0 1994 2020
Entrez Id: 6648
Gene Symbol: SOD2
SOD2 		P04179 superoxide dismutase 2 Enzyme 285 0.379 0.923 0.15 0.320 None 1.000 1 0 2014 2018
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		P35354 prostaglandin-endoperoxide synthase 2 Enzyme 239 0.314 0.962 1.00 0.400 None 0.946 3 0 1996 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 232 0.236 0.962 0.53 0.500 None 0.966 3 1 1991 2020
Entrez Id: 3553
Gene Symbol: IL1B
IL1B 		P01584 interleukin 1 beta 231 0.276 0.962 0.13 0.400 None 1.000 3 0 1993 2020
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		P42898 methylenetetrahydrofolate reductase 192 0.337 0.885 3.2E-10 0.400 None 0.957 1 0 1999 2015
Entrez Id: 4843
Gene Symbol: NOS2
NOS2 		P35228 nitric oxide synthase 2 184 0.364 0.923 4.0E-15 0.340 None 1.000 2 0 2005 2012
Entrez Id: 3458
Gene Symbol: IFNG
IFNG 		P01579 interferon gamma 167 0.288 0.962 0.47 0.400 None 1.000 1 0 1993 2019
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		P15692 vascular endothelial growth factor A Signaling 167 0.266 0.923 2.4E-05 0.600 None 0.964 1 0 1995 2019
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		P01116 KRAS proto-oncogene, GTPase Enzyme modulator 164 0.320 0.923 7.9E-04 0.500 None 0.981 6 0 1991 2019
Entrez Id: 596
Gene Symbol: BCL2
BCL2 		P10415 BCL2 apoptosis regulator Signaling 141 0.291 0.885 0.56 0.600 None 1.000 3 0 1997 2019
Entrez Id: 4318
Gene Symbol: MMP9
MMP9 		P14780 matrix metallopeptidase 9 Enzyme 138 0.305 0.923 1.9E-17 0.400 None 0.966 1 0 1996 2019
Entrez Id: 6774
Gene Symbol: STAT3
STAT3 		P40763 signal transducer and activator of transcription 3 Nucleic acid binding 138 0.320 0.923 1.00 0.400 None 0.978 1 0 2005 2019
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		P35222 catenin beta 1 130 0.303 0.885 1.00 0.400 None 0.995 9 0 1997 2020
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		P00533 epidermal growth factor receptor Kinase 124 0.295 0.885 0.37 0.400 None 0.979 2 0 1989 2019
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 115 0.319 0.846 1.00 0.400 None 0.971 0 2 2003 2019
Entrez Id: 3952
Gene Symbol: LEP
LEP 		P41159 leptin 114 0.349 0.846 0.46 0.400 None 1.000 1 0 2005 2018
Entrez Id: 5020
Gene Symbol: OXT
OXT 		P01178 oxytocin/neurophysin I prepropeptide Signaling 110 0.615 0.423 0.71 0.300 None 1.000 1 0 1996 1996
Entrez Id: 5468
Gene Symbol: PPARG
PPARG 		P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 110 0.358 0.885 2.9E-02 0.600 None 1.000 1 2 1998 2019
Entrez Id: 8314
Gene Symbol: BAP1
BAP1 		Q92560 BRCA1 associated protein 1 Enzyme 108 0.454 0.731 0.99 0.310 None 1.000 1 0 2015 2019
Entrez Id: 595
Gene Symbol: CCND1
CCND1 		P24385 cyclin D1 Enzyme modulator 96 0.344 0.923 0.89 0.400 None 0.958 4 0 2001 2018
Entrez Id: 324
Gene Symbol: APC
APC 		P25054 APC regulator of WNT signaling pathway 95 0.373 0.962 1.00 0.500 None 0.948 7 4 1992 2019
Entrez Id: 6513
Gene Symbol: SLC2A1
SLC2A1 		P11166 solute carrier family 2 member 1 Transporter 94 0.388 0.808 0.99 0.380 None 1.000 1 0 1996 2020
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN 		P18510 interleukin 1 receptor antagonist 92 0.373 0.923 3.1E-02 0.320 None 1.000 1 0 2005 2017
Entrez Id: 4609
Gene Symbol: MYC
MYC 		P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 91 0.344 0.923 1.00 0.400 None 0.960 4 0 1984 2019