Source: CURATED ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 4292
Gene Symbol: MLH1
MLH1 		P40692 mutL homolog 1 Nucleic acid binding 31 0.399 0.808 3.4E-05 0.500 None 0.990 1 10 1988 2020
Entrez Id: 324
Gene Symbol: APC
APC 		P25054 APC regulator of WNT signaling pathway 95 0.373 0.962 1.00 0.500 None 0.948 7 4 1992 2019
Entrez Id: 894
Gene Symbol: CCND2
CCND2 		P30279 cyclin D2 Enzyme modulator 42 0.477 0.808 0.99 0.610 None 1.000 1 3 2004 2019
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2 		O96017 checkpoint kinase 2 Kinase 47 0.460 0.808 1.2E-24 0.470 None 0.857 0 3 2001 2009
Entrez Id: 5468
Gene Symbol: PPARG
PPARG 		P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 110 0.358 0.885 2.9E-02 0.600 None 1.000 1 2 1998 2019
Entrez Id: 6934
Gene Symbol: TCF7L2
TCF7L2 		Q9NQB0 transcription factor 7 like 2 29 0.485 0.846 1.00 0.480 None 1.000 1 2 2005 2019
Entrez Id: 5606
Gene Symbol: MAP2K3
MAP2K3 		P46734 mitogen-activated protein kinase kinase 3 Kinase 1 0.619 0.615 2.2E-02 0.300 None 0 2
Entrez Id: 5795
Gene Symbol: PTPRJ
PTPRJ 		Q12913 protein tyrosine phosphatase receptor type J Enzyme 8 0.606 0.615 1.3E-11 0.350 None 1.000 0 2 2002 2010
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 115 0.319 0.846 1.00 0.400 None 0.971 0 2 2003 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 232 0.236 0.962 0.53 0.500 None 0.966 3 1 1991 2020
Entrez Id: 5782
Gene Symbol: PTPN12
PTPN12 		Q05209 protein tyrosine phosphatase non-receptor type 12 2 0.641 0.769 1.00 0.510 None 1.000 1 1 1994 2018
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		Q9UIF7 mutY DNA glycosylase Enzyme 19 0.521 0.769 1.3E-18 0.500 None 1.000 1 1 2005 2018
Entrez Id: 25788
Gene Symbol: RAD54B
RAD54B 		O95073 Q9Y620 RAD54 homolog B 13 0.659 0.462 8.1E-13 0.320 None 1.000 0 1 1999 2002
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		P35222 catenin beta 1 130 0.303 0.885 1.00 0.400 None 0.995 9 0 1997 2020
Entrez Id: 7298
Gene Symbol: TYMS
TYMS 		P04818 thymidylate synthetase Enzyme 67 0.425 0.846 0.72 0.400 None 0.979 6 0 1993 2019
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		P01116 KRAS proto-oncogene, GTPase Enzyme modulator 164 0.320 0.923 7.9E-04 0.500 None 0.981 6 0 1991 2019
Entrez Id: 595
Gene Symbol: CCND1
CCND1 		P24385 cyclin D1 Enzyme modulator 96 0.344 0.923 0.89 0.400 None 0.958 4 0 2001 2018
Entrez Id: 4609
Gene Symbol: MYC
MYC 		P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 91 0.344 0.923 1.00 0.400 None 0.960 4 0 1984 2019
Entrez Id: 240
Gene Symbol: ALOX5
ALOX5 		P09917 arachidonate 5-lipoxygenase Enzyme 64 0.447 0.885 1.2E-06 0.370 None 0.889 3 0 2004 2018
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		P35354 prostaglandin-endoperoxide synthase 2 Enzyme 239 0.314 0.962 1.00 0.400 None 0.946 3 0 1996 2019
Entrez Id: 3553
Gene Symbol: IL1B
IL1B 		P01584 interleukin 1 beta 231 0.276 0.962 0.13 0.400 None 1.000 3 0 1993 2020
Entrez Id: 596
Gene Symbol: BCL2
BCL2 		P10415 BCL2 apoptosis regulator Signaling 141 0.291 0.885 0.56 0.600 None 1.000 3 0 1997 2019
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1 		P05362 intercellular adhesion molecule 1 57 0.364 0.962 3.5E-02 0.350 None 0.833 2 0 1993 2015
Entrez Id: 5111
Gene Symbol: PCNA
PCNA 		P12004 proliferating cell nuclear antigen Nucleic acid binding 26 0.382 0.846 0.98 0.350 None 1.000 2 0 1998 2014
Entrez Id: 4843
Gene Symbol: NOS2
NOS2 		P35228 nitric oxide synthase 2 184 0.364 0.923 4.0E-15 0.340 None 1.000 2 0 2005 2012