Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog Enzyme 182 0.305 0.923 0.26 0.600 None 0.988 0 0 1999 2019
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
P35222 catenin beta 1 130 0.303 0.885 1.00 0.400 None 1.000 0 0 1996 2019
Entrez Id: 5426
Gene Symbol: POLE
POLE
Q07864 DNA polymerase epsilon, catalytic subunit 17 0.526 0.731 8.0E-27 0.400 None 1.000 0 0 2013 2020
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
P43246 mutS homolog 2 Nucleic acid binding 24 0.406 0.808 0.90 0.400 None 0.898 0 0 1994 2018
Entrez Id: 4292
Gene Symbol: MLH1
MLH1
P40692 mutL homolog 1 Nucleic acid binding 31 0.399 0.808 3.4E-05 0.400 None 0.947 0 0 1996 2019
Entrez Id: 5395
Gene Symbol: PMS2
PMS2
P54278 PMS1 homolog 2, mismatch repair system component Nucleic acid binding 31 0.484 0.808 4.5E-27 0.400 None 1.000 0 0 2010 2019
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
P52701 mutS homolog 6 Nucleic acid binding 29 0.462 0.731 3.7E-05 0.400 None 0.974 0 0 2000 2020
Entrez Id: 2263
Gene Symbol: FGFR2
FGFR2
P21802 fibroblast growth factor receptor 2 Kinase 93 0.380 0.808 1.00 0.400 None 0.950 0 0 2008 2019
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor Kinase 124 0.295 0.885 0.37 0.400 None 0.944 0 0 1995 2018
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
Q969H0 F-box and WD repeat domain containing 7 Enzyme modulator 23 0.465 0.808 1.00 0.340 None 1.000 0 0 2002 2019
Entrez Id: 8405
Gene Symbol: SPOP
SPOP
O43791 speckle type BTB/POZ protein 8 0.597 0.500 1.00 0.330 None 1.000 0 0 2015 2018
Entrez Id: 5296
Gene Symbol: PIK3R2
PIK3R2
O00459 phosphoinositide-3-kinase regulatory subunit 2 Enzyme modulator 9 0.551 0.808 1.6E-02 0.320 None 1.000 0 0 2011 2011
Entrez Id: 545
Gene Symbol: ATR
ATR
Q13535 ATR serine/threonine kinase Kinase 30 0.456 0.923 3.5E-09 0.310 None 1.000 0 0 2019 2019
Entrez Id: 4149
Gene Symbol: MAX
MAX
P61244 MYC associated factor X Transcription factor 11 0.553 0.769 0.83 0.310 None 1.000 0 0 2018 2018
Entrez Id: 5378
Gene Symbol: PMS1
PMS1
P54277 PMS1 homolog 1, mismatch repair system component Nucleic acid binding 13 0.569 0.654 1.3E-17 0.310 None 1.000 0 0 2019 2019
Entrez Id: 1523
Gene Symbol: CUX1
CUX1
P39880 Q13948 cut like homeobox 1 Transcription factor 14 0.465 0.846 1.00 0.300 None 0 0
Entrez Id: 5885
Gene Symbol: RAD21
RAD21
O60216 RAD21 cohesin complex component 17 0.528 0.846 1.00 0.300 None 0 0
Entrez Id: 8312
Gene Symbol: AXIN1
AXIN1
O15169 axin 1 10 0.559 0.577 0.41 0.300 None 0 0