Source: BEFREE ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A 		Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 953 0.327 0.923 0.98 0.340 None 1.000 4 0 2008 2020
Entrez Id: 6513
Gene Symbol: SLC2A1
SLC2A1 		P11166 solute carrier family 2 member 1 Transporter 506 0.388 0.808 0.99 0.340 None 1.000 4 0 2010 2020
Entrez Id: 768
Gene Symbol: CA9
CA9 		Q16790 carbonic anhydrase 9 211 0.483 0.731 1.3E-09 0.330 None 1.000 3 0 2010 2020
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		P51587 BRCA2 DNA repair associated Nucleic acid binding 459 0.379 0.846 2.4E-25 0.200 None 1.000 18 1 2003 2019
Entrez Id: 472
Gene Symbol: ATM
ATM 		Q13315 ATM serine/threonine kinase Kinase 563 0.374 0.885 5.6E-47 0.110 None 1.000 1 0 1996 1996
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		P04626 erb-b2 receptor tyrosine kinase 2 Kinase 942 0.328 0.923 6.0E-03 0.100 None 0.992 117 0 1988 2020
Entrez Id: 2099
Gene Symbol: ESR1
ESR1 		P03372 estrogen receptor 1 Nuclear receptor 972 0.324 0.962 1.00 0.100 None 1.000 42 0 2000 2020
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 2245 0.236 0.962 0.53 0.100 None 0.975 40 0 1994 2019
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1 		P38398 BRCA1 DNA repair associated Enzyme 576 0.367 0.923 9.2E-29 0.100 None 1.000 21 0 1995 2019
Entrez Id: 4000
Gene Symbol: LMNA
LMNA 		P02545 lamin A/C 401 0.384 0.885 1.00 0.100 None 0.952 21 0 2000 2019
Entrez Id: 5241
Gene Symbol: PGR
PGR 		P06401 progesterone receptor Nuclear receptor 341 0.426 0.885 5.1E-02 0.100 None 1.000 16 0 1998 2019
Entrez Id: 595
Gene Symbol: CCND1
CCND1 		P24385 cyclin D1 Enzyme modulator 748 0.344 0.923 0.89 0.100 None 0.929 14 0 1997 2016
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1277 0.292 0.923 1.00 0.090 None 0.778 9 0 2010 2019
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		P00533 epidermal growth factor receptor Kinase 1308 0.295 0.885 0.37 0.090 None 1.000 8 0 1998 2018
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1043 0.314 0.962 1.00 0.090 None 0.889 8 0 2002 2019
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		P60484 phosphatase and tensin homolog Enzyme 983 0.305 0.923 0.26 0.080 None 1.000 8 0 2004 2019
Entrez Id: 1588
Gene Symbol: CYP19A1
CYP19A1 		P11511 cytochrome P450 family 19 subfamily A member 1 Enzyme 448 0.410 0.885 1.7E-05 0.080 None 1.000 8 0 2008 2017
Entrez Id: 596
Gene Symbol: BCL2
BCL2 		P10415 BCL2 apoptosis regulator Signaling 1294 0.291 0.885 0.56 0.070 None 1.000 7 0 1997 2011
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		P15692 vascular endothelial growth factor A Signaling 1737 0.266 0.923 2.4E-05 0.070 None 1.000 7 0 1995 2011
Entrez Id: 6278
Gene Symbol: S100A7
S100A7 		P31151 S100 calcium binding protein A7 Calcium-binding protein 113 0.546 0.769 0.45 0.060 None 0.667 6 0 2002 2017
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		P42771 Q8N726 cyclin dependent kinase inhibitor 2A 1214 0.300 0.885 0.39 0.060 None 1.000 6 0 2003 2014
Entrez Id: 11186
Gene Symbol: RASSF1
RASSF1 		Q9NS23 Ras association domain family member 1 Enzyme modulator 378 0.420 0.808 4.9E-06 0.060 None 1.000 6 0 2003 2017
Entrez Id: 7405
Gene Symbol: UVRAG
UVRAG 		Q9P2Y5 UV radiation resistance associated 334 0.436 0.769 0.99 0.050 None 1.000 5 0 2002 2018
Entrez Id: 10970
Gene Symbol: CKAP4
CKAP4 		Q07065 cytoskeleton associated protein 4 332 0.436 0.731 0.51 0.050 None 1.000 5 0 2002 2018
Entrez Id: 367
Gene Symbol: AR
AR 		P10275 androgen receptor Nuclear receptor 762 0.351 0.846 0.99 0.050 None 1.000 5 0 2011 2019