Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor Kinase 1394 0.295 0.885 0.37 0.700 None 0.976 4060 54 1989 2020
Entrez Id: 673
Gene Symbol: BRAF
BRAF
P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1228 0.319 0.846 1.00 0.500 None 1.000 127 17 2002 2020
Entrez Id: 100507500
Gene Symbol: EGFR-AS1
EGFR-AS1
EGFR antisense RNA 1 20 0.722 0.192 0.130 None 1.000 20 15 2004 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.400 None 0.972 424 13 1990 2020
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
P01116 KRAS proto-oncogene, GTPase Enzyme modulator 1213 0.320 0.923 7.9E-04 0.700 None 0.979 529 12 1989 2020
Entrez Id: 238
Gene Symbol: ALK
ALK
Q9UM73 ALK receptor tyrosine kinase Kinase 519 0.396 0.846 3.2E-06 0.600 None 0.990 1046 11 2007 2020
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 Kinase 995 0.328 0.923 6.0E-03 0.500 None 0.974 154 11 1989 2020
Entrez Id: 2068
Gene Symbol: ERCC2
ERCC2
P18074 ERCC excision repair 2, TFIIH core complex helicase subunit Enzyme 499 0.420 0.846 7.1E-20 0.100 None 0.958 24 11 2001 2017
Entrez Id: 4233
Gene Symbol: MET
MET
P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 594 0.380 0.846 0.97 0.600 None 0.986 216 7 2002 2020
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1511 0.292 0.923 1.00 0.500 None 0.990 191 7 2003 2019
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1193 0.320 0.923 1.00 0.400 None 1.000 110 7 2003 2020
Entrez Id: 7015
Gene Symbol: TERT
TERT
O14746 telomerase reverse transcriptase Enzyme 703 0.374 0.846 0.99 0.400 None 0.968 31 7 2000 2020
Entrez Id: 4683
Gene Symbol: NBN
NBN
O60934 nibrin Nucleic acid binding 291 0.467 0.808 2.2E-16 0.040 None 1.000 4 7 2006 2014
Entrez Id: 1600
Gene Symbol: DAB1
DAB1
O75553 DAB adaptor protein 1 Signaling 81 0.626 0.615 1.00 0.100 None 1.000 1 7 2012 2012
Entrez Id: 7515
Gene Symbol: XRCC1
XRCC1
P18887 X-ray repair cross complementing 1 410 0.421 0.923 6.3E-09 0.100 None 0.980 51 6 2001 2019
Entrez Id: 2067
Gene Symbol: ERCC1
ERCC1
P07992 ERCC excision repair 1, endonuclease non-catalytic subunit Enzyme 345 0.445 0.846 1.6E-07 0.400 None 0.963 164 5 2002 2020
Entrez Id: 9429
Gene Symbol: ABCG2
ABCG2
Q9UNQ0 ATP binding cassette subfamily G member 2 (Junior blood group) Transporter 420 0.419 0.885 2.1E-32 0.100 None 0.963 27 5 2003 2019
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
P42898 methylenetetrahydrofolate reductase 985 0.337 0.885 3.2E-10 0.100 None 1.000 13 5 2004 2017
Entrez Id: 8626
Gene Symbol: TP63
TP63
Q9H3D4 tumor protein p63 Transcription factor 816 0.362 0.769 1.00 0.100 None 0.846 13 5 1999 2019
Entrez Id: 2073
Gene Symbol: ERCC5
ERCC5
P28715 ERCC excision repair 5, endonuclease 238 0.499 0.731 2.7E-13 0.100 None 1.000 12 5 2006 2017
Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
O15392 baculoviral IAP repeat containing 5 Enzyme modulator 199 0.495 0.731 5.6E-02 0.350 None 1.000 6 5 2005 2020
Entrez Id: 7518
Gene Symbol: XRCC4
XRCC4
Q13426 X-ray repair cross complementing 4 192 0.528 0.769 8.3E-07 0.030 None 1.000 3 5 2009 2013
Entrez Id: 8863
Gene Symbol: PER3
PER3
P56645 period circadian regulator 3 Transcription factor 122 0.559 0.731 1.4E-17 0.020 None 1.000 2 5 2014 2017
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
P01137 transforming growth factor beta 1 Signaling 1558 0.287 0.962 3.7E-02 0.100 None 0.971 69 4 1997 2020
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
P08183 ATP binding cassette subfamily B member 1 Transporter 933 0.344 0.885 1.3E-05 0.400 None 0.952 63 4 1989 2020