Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 23583
Gene Symbol: SMUG1
SMUG1 		Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 1034 0.322 0.923 4.5E-04 0.100 None 0.972 72 0 2017 2020
Entrez Id: 406991
Gene Symbol: MIR21
MIR21 		microRNA 21 726 0.363 0.846 0.100 None 0.971 69 0 2008 2020
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1 		P01137 transforming growth factor beta 1 Signaling 1558 0.287 0.962 3.7E-02 0.100 None 0.971 69 4 1997 2020
Entrez Id: 7864
Gene Symbol: SCLC1
SCLC1 		small cell cancer of the lung 73 0.612 0.577 0.100 None 0.913 69 0 1989 2020
Entrez Id: 6794
Gene Symbol: STK11
STK11 		Q15831 serine/threonine kinase 11 Kinase 372 0.435 0.808 0.99 0.500 None 0.985 68 2 2006 2020
Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5 		P06731 CEA cell adhesion molecule 5 428 0.420 0.846 4.2E-10 0.100 None 0.985 66 0 1992 2019
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1 		P28482 mitogen-activated protein kinase 1 Kinase 1059 0.330 0.923 1.00 0.100 None 1.000 64 0 2000 2020
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1 		P08183 ATP binding cassette subfamily B member 1 Transporter 933 0.344 0.885 1.3E-05 0.400 None 0.952 63 4 1989 2020
Entrez Id: 5979
Gene Symbol: RET
RET 		P07949 ret proto-oncogene Kinase 607 0.392 0.885 1.00 0.400 None 1.000 62 0 2010 2020
Entrez Id: 7298
Gene Symbol: TYMS
TYMS 		P04818 thymidylate synthetase Enzyme 406 0.425 0.846 0.72 0.100 None 0.983 60 1 2002 2020
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A 		Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 1044 0.327 0.923 0.98 0.400 None 0.914 58 4 2005 2019
Entrez Id: 6240
Gene Symbol: RRM1
RRM1 		P23921 ribonucleotide reductase catalytic subunit M1 Enzyme 111 0.552 0.692 1.00 0.400 None 0.966 58 2 2004 2019
Entrez Id: 11186
Gene Symbol: RASSF1
RASSF1 		Q9NS23 Ras association domain family member 1 Enzyme modulator 400 0.420 0.808 4.9E-06 0.400 None 0.947 57 0 2001 2020
Entrez Id: 5609
Gene Symbol: MAP2K7
MAP2K7 		O14733 mitogen-activated protein kinase kinase 7 Kinase 408 0.419 0.808 1.00 0.100 None 0.982 57 2 2011 2020
Entrez Id: 4318
Gene Symbol: MMP9
MMP9 		P14780 matrix metallopeptidase 9 Enzyme 1337 0.305 0.923 1.9E-17 0.400 None 0.964 56 2 2004 2019
Entrez Id: 115482713
Gene Symbol: H3P10
H3P10 		H3 histone pseudogene 10 769 0.350 0.846 0.100 None 0.963 54 0 1995 2020
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2 		Q16236 nuclear factor, erythroid 2 like 2 Enzyme 823 0.357 0.885 3.6E-03 0.600 None 0.962 53 0 2006 2020
Entrez Id: 595
Gene Symbol: CCND1
CCND1 		P24385 cyclin D1 Enzyme modulator 859 0.344 0.923 0.89 0.100 None 0.981 52 0 1996 2019
Entrez Id: 7124
Gene Symbol: TNF
TNF 		P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.100 None 0.962 52 1 1999 2019
Entrez Id: 7515
Gene Symbol: XRCC1
XRCC1 		P18887 X-ray repair cross complementing 1 410 0.421 0.923 6.3E-09 0.100 None 0.980 51 6 2001 2019
Entrez Id: 3569
Gene Symbol: IL6
IL6 		P05231 interleukin 6 2367 0.248 0.962 0.32 0.100 None 0.980 50 0 1998 2020
Entrez Id: 3082
Gene Symbol: HGF
HGF 		P14210 hepatocyte growth factor Enzyme 671 0.374 0.885 1.00 0.100 None 0.980 49 0 1998 2019
Entrez Id: 4513
Gene Symbol: COX2
COX2 		P00403 cytochrome c oxidase subunit II Enzyme 875 0.352 0.962 0.100 None 0.979 47 0 2000 2020
Entrez Id: 1493
Gene Symbol: CTLA4
CTLA4 		P16410 cytotoxic T-lymphocyte associated protein 4 722 0.369 0.923 0.94 0.100 None 0.978 46 3 2009 2019
Entrez Id: 2146
Gene Symbol: EZH2
EZH2 		Q15910 enhancer of zeste 2 polycomb repressive complex 2 subunit Epigenetic regulator 653 0.376 0.885 1.00 0.100 None 1.000 46 0 2010 2020