Source: CURATED ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		P00533 epidermal growth factor receptor Kinase 124 0.295 0.885 0.37 0.700 None 0.976 16 29 1989 2020
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		P01116 KRAS proto-oncogene, GTPase Enzyme modulator 164 0.320 0.923 7.9E-04 0.700 None 0.979 7 10 1989 2020
Entrez Id: 238
Gene Symbol: ALK
ALK 		Q9UM73 ALK receptor tyrosine kinase Kinase 45 0.396 0.846 3.2E-06 0.600 None 0.990 28 0 2007 2020
Entrez Id: 4233
Gene Symbol: MET
MET 		P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 90 0.380 0.846 0.97 0.600 None 0.986 4 0 2002 2020
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		P42771 Q8N726 cyclin dependent kinase inhibitor 2A 115 0.300 0.885 0.39 0.600 None 0.957 2 3 1994 2020
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2 		Q16236 nuclear factor, erythroid 2 like 2 Enzyme 89 0.357 0.885 3.6E-03 0.600 None 0.962 2 0 2006 2020
Entrez Id: 55743
Gene Symbol: CHFR
CHFR 		Q96EP1 checkpoint with forkhead and ring finger domains Enzyme 6 0.633 0.500 7.9E-04 0.550 None 0.800 1 1 2008 2015
Entrez Id: 841
Gene Symbol: CASP8
CASP8 		Q14790 caspase 8 Enzyme 58 0.404 0.923 3.7E-06 0.500 None 1.000 1 1 2007 2019
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 98 0.292 0.923 1.00 0.500 None 0.990 0 7 2003 2019
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		P04626 erb-b2 receptor tyrosine kinase 2 Kinase 83 0.328 0.923 6.0E-03 0.500 None 0.974 0 9 1989 2020
Entrez Id: 6794
Gene Symbol: STK11
STK11 		Q15831 serine/threonine kinase 11 Kinase 39 0.435 0.808 0.99 0.500 None 0.985 0 1 2006 2020
Entrez Id: 5604
Gene Symbol: MAP2K1
MAP2K1 		Q02750 mitogen-activated protein kinase kinase 1 Kinase 30 0.439 0.846 0.90 0.500 None 1.000 0 3 1995 2019
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 115 0.319 0.846 1.00 0.500 None 1.000 0 15 2002 2020
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		P60484 phosphatase and tensin homolog Enzyme 182 0.305 0.923 0.26 0.500 None 1.000 0 1 1998 2020
Entrez Id: 81037
Gene Symbol: CLPTM1L
CLPTM1L 		Q96KA5 CLPTM1 like Enzyme 16 0.551 0.654 4.4E-05 0.470 None 0.875 1 1 2012 2019
Entrez Id: 4893
Gene Symbol: NRAS
NRAS 		P01111 NRAS proto-oncogene, GTPase Enzyme modulator 67 0.390 0.808 0.49 0.460 None 1.000 0 4 1984 2019
Entrez Id: 208
Gene Symbol: AKT2
AKT2 		P31751 AKT serine/threonine kinase 2 Kinase 27 0.474 0.769 0.64 0.460 None 1.000 0 1 2010 2018
Entrez Id: 27436
Gene Symbol: EML4
EML4 		Q9HC35 EMAP like 4 10 0.569 0.577 4.8E-04 0.400 None 0.994 6 0 2007 2020
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 232 0.236 0.962 0.53 0.400 None 0.972 4 0 1990 2020
Entrez Id: 6098
Gene Symbol: ROS1
ROS1 		P08922 ROS proto-oncogene 1, receptor tyrosine kinase Kinase 9 0.439 0.885 1.6E-72 0.400 None 0.989 4 0 2009 2020
Entrez Id: 2067
Gene Symbol: ERCC1
ERCC1 		P07992 ERCC excision repair 1, endonuclease non-catalytic subunit Enzyme 42 0.445 0.846 1.6E-07 0.400 None 0.963 2 0 2002 2020
Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1 		P11362 fibroblast growth factor receptor 1 Kinase 87 0.362 0.885 1.00 0.400 None 0.917 2 0 1999 2020
Entrez Id: 2305
Gene Symbol: FOXM1
FOXM1 		Q08050 forkhead box M1 17 0.441 0.769 7.4E-04 0.400 None 1.000 2 0 2008 2020
Entrez Id: 4193
Gene Symbol: MDM2
MDM2 		Q00987 MDM2 proto-oncogene Nucleic acid binding 25 0.362 0.846 1.00 0.400 None 1.000 2 0 1995 2019
Entrez Id: 1728
Gene Symbol: NQO1
NQO1 		P15559 NAD(P)H quinone dehydrogenase 1 52 0.434 0.885 1.2E-09 0.400 None 1.000 2 0 1992 2019