Source: BEFREE ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 5327
Gene Symbol: PLAT
PLAT 		P00750 plasminogen activator, tissue type Enzyme 255 0.445 0.885 5.7E-05 0.390 None 1.000 9 0 1991 2019
Entrez Id: 241
Gene Symbol: ALOX5AP
ALOX5AP 		P20292 arachidonate 5-lipoxygenase activating protein Enzyme 55 0.612 0.731 7.1E-02 0.370 None 0.714 7 6 2008 2015
Entrez Id: 4846
Gene Symbol: NOS3
NOS3 		P29474 nitric oxide synthase 3 559 0.378 0.885 6.7E-07 0.360 None 1.000 6 1 2002 2019
Entrez Id: 2147
Gene Symbol: F2
F2 		P00734 coagulation factor II, thrombin Enzyme 393 0.415 0.885 1.1E-03 0.350 None 1.000 5 2 1999 2009
Entrez Id: 2153
Gene Symbol: F5
F5 		P12259 coagulation factor V Enzyme 282 0.441 0.846 5.9E-15 0.340 None 1.000 3 1 1995 2009
Entrez Id: 5583
Gene Symbol: PRKCH
PRKCH 		P24723 protein kinase C eta Kinase 30 0.653 0.577 0.43 0.330 None 1.000 3 0 2007 2011
Entrez Id: 5328
Gene Symbol: PLAU
PLAU 		P00749 plasminogen activator, urokinase Enzyme 301 0.425 0.923 2.3E-06 0.310 None 1.000 1 0 2002 2019
Entrez Id: 7421
Gene Symbol: VDR
VDR 		P11473 vitamin D receptor Nuclear receptor 757 0.352 0.885 1.7E-05 0.310 None 1.000 1 0 2009 2015
Entrez Id: 125
Gene Symbol: ADH1B
ADH1B 		P00325 alcohol dehydrogenase 1B (class I), beta polypeptide Enzyme 189 0.502 0.846 9.9E-07 0.310 None 1.000 1 0 2004 2004
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1 		P05121 serpin family E member 1 Enzyme modulator 706 0.359 0.885 4.4E-02 0.260 None 1.000 6 2 1999 2017
Entrez Id: 4217
Gene Symbol: MAP3K5
MAP3K5 		Q99683 mitogen-activated protein kinase kinase kinase 5 Kinase 146 0.513 0.808 0.52 0.240 None 1.000 4 0 2013 2018
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1 		P05362 intercellular adhesion molecule 1 641 0.364 0.962 3.5E-02 0.240 None 1.000 3 0 2002 2019
Entrez Id: 4133
Gene Symbol: MAP2
MAP2 		P11137 microtubule associated protein 2 96 0.537 0.692 1.00 0.220 None 1.000 2 0 2012 2020
Entrez Id: 301
Gene Symbol: ANXA1
ANXA1 		P04083 annexin A1 300 0.442 0.885 1.2E-07 0.220 None 1.000 2 0 2012 2019
Entrez Id: 3606
Gene Symbol: IL18
IL18 		Q14116 interleukin 18 673 0.365 0.923 3.1E-02 0.210 None 1.000 1 0 2010 2019
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		P15692 vascular endothelial growth factor A Signaling 1737 0.266 0.923 2.4E-05 0.100 None 1.000 29 1 2005 2019
Entrez Id: 4318
Gene Symbol: MMP9
MMP9 		P14780 matrix metallopeptidase 9 Enzyme 1160 0.305 0.923 1.9E-17 0.100 None 0.905 21 0 2003 2019
Entrez Id: 7124
Gene Symbol: TNF
TNF 		P01375 tumor necrosis factor Signaling 2475 0.231 0.962 0.80 0.100 None 1.000 18 0 2003 2019
Entrez Id: 348
Gene Symbol: APOE
APOE 		P02649 apolipoprotein E 886 0.338 0.962 1.9E-03 0.100 None 0.889 17 0 1998 2019
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB 		P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1077 0.322 0.885 1.00 0.100 None 1.000 16 0 2012 2019
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1105 0.319 0.885 1.00 0.100 None 1.000 16 0 2012 2019
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG 		P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1087 0.320 0.885 1.4E-06 0.100 None 1.000 16 0 2012 2019
Entrez Id: 627
Gene Symbol: BDNF
BDNF 		P23560 brain derived neurotrophic factor Signaling 852 0.345 0.923 0.66 0.100 None 1.000 16 0 2004 2019
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1277 0.292 0.923 1.00 0.100 None 1.000 16 0 2012 2019
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2 		Q16236 nuclear factor, erythroid 2 like 2 Enzyme 739 0.357 0.885 3.6E-03 0.100 None 1.000 16 0 2017 2020