Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 84 0.236 0.962 0.53 0.470 None 1.000 1 8 1999 2016
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
P35222 catenin beta 1 70 0.303 0.885 1.00 0.410 None 1.000 1 4 2001 2016
Entrez Id: 2475
Gene Symbol: MTOR
MTOR
P42345 mechanistic target of rapamycin kinase Kinase 86 0.343 0.885 1.00 0.400 None 1.000 1 2 2008 2016
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
P01112 HRas proto-oncogene, GTPase Enzyme modulator 71 0.378 0.885 8.0E-02 0.400 None 1.000 1 6 2016 2016
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog Enzyme 107 0.305 0.923 0.26 0.110 None 1.000 1 2 2004 2016
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 85 0.292 0.923 1.00 0.110 None 1.000 1 23 2015 2016
Entrez Id: 1387
Gene Symbol: CREBBP
CREBBP
Q92793 CREB binding protein 40 0.428 0.808 1.00 0.100 None 1.000 1 2 2016 2016
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1
P28482 mitogen-activated protein kinase 1 Kinase 3 0.330 0.923 1.00 0.100 None 1.000 1 1 2016 2016
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
Q969H0 F-box and WD repeat domain containing 7 Enzyme modulator 18 0.465 0.808 1.00 0.100 None 1.000 1 7 2016 2016
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
Q16236 nuclear factor, erythroid 2 like 2 Enzyme 10 0.357 0.885 3.6E-03 0.100 None 1.000 1 5 2016 2016
Entrez Id: 4089
Gene Symbol: SMAD4
SMAD4
Q13485 SMAD family member 4 Transcription factor 16 0.401 0.808 1.00 0.100 None 1.000 1 2 2016 2016
Entrez Id: 2778
Gene Symbol: GNAS
GNAS
O95467 P63092 P84996 Q5JWF2 GNAS complex locus Enzyme modulator 60 0.420 0.885 0.68 0.100 None 1.000 1 2 2016 2016
Entrez Id: 2065
Gene Symbol: ERBB3
ERBB3
P21860 erb-b2 receptor tyrosine kinase 3 Kinase 12 0.448 0.808 1.7E-15 0.100 None 1.000 1 1 2016 2016
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 Kinase 23 0.328 0.923 6.0E-03 0.100 None 1.000 1 2 2016 2016
Entrez Id: 2033
Gene Symbol: EP300
EP300
Q09472 E1A binding protein p300 28 0.459 0.846 1.00 0.100 None 1.000 1 1 2016 2016
Entrez Id: 7307
Gene Symbol: U2AF1
U2AF1
P0DN76 Q01081 U2 small nuclear RNA auxiliary factor 1 Nucleic acid binding 9 0.604 0.577 0.99 0.100 None 1.000 1 1 2016 2016