Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3
Q96P20 NLR family pyrin domain containing 3 805 0.361 0.962 8.1E-04 0.050 None 1.000 5 0 2017 2019
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.340 None 1.000 5 0 2010 2019
Entrez Id: 847
Gene Symbol: CAT
CAT
P04040 catalase Enzyme 794 0.359 0.962 1.6E-10 0.520 None 1.000 4 0 2011 2019
Entrez Id: 3552
Gene Symbol: IL1A
IL1A
P01583 interleukin 1 alpha 1002 0.333 0.962 1.6E-04 0.210 None 1.000 2 0 2010 2017
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
P01584 interleukin 1 beta 1801 0.276 0.962 0.13 0.020 None 1.000 2 0 2017 2018
Entrez Id: 3565
Gene Symbol: IL4
IL4
P05112 interleukin 4 996 0.332 0.962 4.7E-03 0.210 None 1.000 2 0 1999 2010
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 2367 0.248 0.962 0.32 0.310 None 1.000 2 0 2012 2015
Entrez Id: 207
Gene Symbol: AKT1
AKT1
P31749 AKT serine/threonine kinase 1 Kinase 1250 0.311 0.962 0.98 0.010 None 1.000 1 0 2018 2018
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
P03372 estrogen receptor 1 Nuclear receptor 1101 0.324 0.962 1.00 0.010 None 1.000 1 0 2015 2015
Entrez Id: 213
Gene Symbol: ALB
ALB
P02768 albumin Transporter 1198 0.317 0.962 0.64 0.010 None 1.000 1 0 2018 2018
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
P05362 intercellular adhesion molecule 1 737 0.364 0.962 3.5E-02 0.300 None 1.000 1 0 2011 2011
Entrez Id: 348
Gene Symbol: APOE
APOE
P02649 apolipoprotein E 1049 0.338 0.962 1.9E-03 0.010 None 1.000 1 0 2019 2019
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
P10145 C-X-C motif chemokine ligand 8 Signaling 1254 0.310 0.962 2.7E-04 0.300 None 1.000 1 0 2011 2011
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.010 None 1.000 1 0 2017 2017
Entrez Id: 960
Gene Symbol: CD44
CD44
P16070 CD44 molecule (Indian blood group) 711 0.363 0.962 2.4E-07 0.200 None 1.000 1 0 2006 2006
Entrez Id: 2875
Gene Symbol: GPT
GPT
P24298 glutamic--pyruvic transaminase Enzyme 511 0.403 0.923 3.6E-19 0.080 None 0.750 8 0 2002 2019
Entrez Id: 1958
Gene Symbol: EGR1
EGR1
P18146 early growth response 1 Nucleic acid binding 378 0.433 0.923 0.35 0.320 None 1.000 3 0 2011 2019
Entrez Id: 5265
Gene Symbol: SERPINA1
SERPINA1
P01009 serpin family A member 1 Enzyme modulator 482 0.410 0.923 6.8E-08 0.320 None 1.000 3 0 1972 2010
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
P09488 glutathione S-transferase mu 1 627 0.380 0.923 2.1E-03 0.210 None 1.000 2 0 2015 2015
Entrez Id: 3579
Gene Symbol: CXCR2
CXCR2
P25025 C-X-C motif chemokine receptor 2 G-protein coupled receptor 335 0.445 0.923 1.4E-02 0.020 None 1.000 2 0 2014 2017
Entrez Id: 4843
Gene Symbol: NOS2
NOS2
P35228 nitric oxide synthase 2 783 0.364 0.923 4.0E-15 0.300 None 1.000 2 0 2003 2010
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1511 0.292 0.923 1.00 0.020 None 1.000 2 0 2017 2018
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1
P28482 mitogen-activated protein kinase 1 Kinase 1059 0.330 0.923 1.00 0.020 None 1.000 2 0 2016 2020
Entrez Id: 60
Gene Symbol: ACTB
ACTB
P60709 actin beta Cellular structure 1110 0.325 0.923 0.99 0.020 None 1.000 2 0 1990 2017
Entrez Id: 1432
Gene Symbol: MAPK14
MAPK14
Q16539 mitogen-activated protein kinase 14 Kinase 626 0.379 0.923 0.37 0.300 None 1.000 1 0 2010 2010