Source: BEFREE ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 324
Gene Symbol: APC
APC 		P25054 APC regulator of WNT signaling pathway 517 0.373 0.962 1.00 0.600 None 0.949 26 6 1990 2019
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1043 0.314 0.962 1.00 0.600 None 1.000 20 0 1996 2019
Entrez Id: 596
Gene Symbol: BCL2
BCL2 		P10415 BCL2 apoptosis regulator Signaling 1294 0.291 0.885 0.56 0.560 None 1.000 3 0 1998 2009
Entrez Id: 4318
Gene Symbol: MMP9
MMP9 		P14780 matrix metallopeptidase 9 Enzyme 1160 0.305 0.923 1.9E-17 0.540 None 1.000 1 0 2005 2011
Entrez Id: 4609
Gene Symbol: MYC
MYC 		P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 747 0.344 0.923 1.00 0.530 None 1.000 2 0 2002 2019
Entrez Id: 1786
Gene Symbol: DNMT1
DNMT1 		P26358 DNA methyltransferase 1 Epigenetic regulator 403 0.406 0.885 1.00 0.520 None 1.000 2 0 2009 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 2245 0.236 0.962 0.53 0.500 None 0.969 43 4 1986 2019
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		P01116 KRAS proto-oncogene, GTPase Enzyme modulator 805 0.320 0.923 7.9E-04 0.400 None 0.971 26 1 1987 2018
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		P35222 catenin beta 1 1156 0.303 0.885 1.00 0.400 None 1.000 19 0 1998 2017
Entrez Id: 4292
Gene Symbol: MLH1
MLH1 		P40692 mutL homolog 1 Nucleic acid binding 446 0.399 0.808 3.4E-05 0.400 None 0.947 12 2 1994 2017
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		P00533 epidermal growth factor receptor Kinase 1308 0.295 0.885 0.37 0.400 None 1.000 10 4 1991 2018
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		P15692 vascular endothelial growth factor A Signaling 1737 0.266 0.923 2.4E-05 0.400 None 0.950 9 1 1999 2019
Entrez Id: 5468
Gene Symbol: PPARG
PPARG 		P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 698 0.358 0.885 2.9E-02 0.400 None 0.923 4 0 2003 2010
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A 		P38936 cyclin dependent kinase inhibitor 1A 408 0.403 0.769 1.9E-03 0.400 None 1.000 3 0 2002 2010
Entrez Id: 581
Gene Symbol: BAX
BAX 		Q07812 BCL2 associated X, apoptosis regulator Signaling 338 0.417 0.885 0.32 0.370 None 1.000 3 0 1997 2007
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		P42898 methylenetetrahydrofolate reductase 816 0.337 0.885 3.2E-10 0.370 None 1.000 3 2 2001 2011
Entrez Id: 7298
Gene Symbol: TYMS
TYMS 		P04818 thymidylate synthetase Enzyme 356 0.425 0.846 0.72 0.360 None 1.000 4 0 1988 2008
Entrez Id: 6774
Gene Symbol: STAT3
STAT3 		P40763 signal transducer and activator of transcription 3 Nucleic acid binding 999 0.320 0.923 1.00 0.360 None 0.857 4 0 2008 2019
Entrez Id: 1045
Gene Symbol: CDX2
CDX2 		Q99626 caudal type homeobox 2 Transcription factor 267 0.458 0.769 0.53 0.360 None 1.000 2 0 2001 2018
Entrez Id: 8743
Gene Symbol: TNFSF10
TNFSF10 		P50591 TNF superfamily member 10 Signaling 412 0.413 0.885 0.13 0.350 None 1.000 4 0 2002 2015
Entrez Id: 8549
Gene Symbol: LGR5
LGR5 		O75473 leucine rich repeat containing G protein-coupled receptor 5 G-protein coupled receptor 129 0.542 0.654 2.5E-08 0.350 None 1.000 4 0 2007 2019
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		P04626 erb-b2 receptor tyrosine kinase 2 Kinase 942 0.328 0.923 6.0E-03 0.350 None 1.000 4 0 1992 2015
Entrez Id: 8842
Gene Symbol: PROM1
PROM1 		O43490 prominin 1 Transporter 412 0.410 0.846 1.9E-22 0.350 None 1.000 2 0 2007 2015
Entrez Id: 6714
Gene Symbol: SRC
SRC 		P12931 SRC proto-oncogene, non-receptor tyrosine kinase Kinase 220 0.467 0.885 1.00 0.350 None 1.000 1 0 2003 2009
Entrez Id: 2520
Gene Symbol: GAST
GAST 		P01350 gastrin 219 0.485 0.808 2.7E-03 0.340 None 1.000 3 0 1986 2007