Gene | UniProt | Gene Full Name | Protein Class | N. diseases g | DSI g | DPI g | pLI | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
P07202 | thyroid peroxidase | Enzyme | 9 | 0.455 | 0.846 | 1.8E-21 | 0.900 | strong | 1.000 | 5 | 1 | 1979 | 2018 | ||||
|
Q9NRD8 | dual oxidase 2 | Enzyme | 9 | 0.533 | 0.769 | 4.5E-56 | 0.900 | strong | 0.976 | 3 | 1 | 2002 | 2019 | ||||
|
P16473 | thyroid stimulating hormone receptor | G-protein coupled receptor | 40 | 0.486 | 0.808 | 3.0E-15 | 0.900 | strong | 0.950 | 2 | 2 | 1996 | 2019 | ||||
|
Q06710 | paired box 8 | 9 | 0.477 | 0.731 | 1.00 | 0.700 | strong | 1.000 | 1 | 0 | 1998 | 2019 | |||||
|
O00358 | forkhead box E1 | Transcription factor | 8 | 0.573 | 0.731 | 0.79 | 0.700 | strong | 1.000 | 1 | 0 | 2002 | 2017 | ||||
|
P01266 | thyroglobulin | Enzyme modulator | 17 | 0.480 | 0.808 | 2.9E-59 | 0.600 | strong | 1.000 | 1 | 0 | 1986 | 2019 | ||||
|
P43699 | NK2 homeobox 1 | Transcription factor | 23 | 0.457 | 0.808 | 0.36 | 0.500 | strong | 1.000 | 1 | 0 | 1995 | 2014 | ||||
|
Q8NEA6 | GLIS family zinc finger 3 | 15 | 0.590 | 0.654 | 5.6E-08 | 0.500 | strong | 1.000 | 1 | 0 | 2006 | 2020 | |||||
|
Q8N6C5 | immunoglobulin superfamily member 1 | Receptor | 9 | 0.608 | 0.500 | 1.00 | 0.500 | None | 1.000 | 1 | 0 | 2012 | 2012 | ||||
|
P01222 | thyroid stimulating hormone subunit beta | Signaling | 15 | 0.670 | 0.538 | 8.4E-03 | 0.400 | strong | 1.000 | 1 | 0 | 2017 | 2017 | ||||
|
Q6PHW0 | iodotyrosine deiodinase | 5 | 0.700 | 0.500 | 4.1E-03 | 0.340 | strong | 1.000 | 1 | 0 | 2003 | 2017 | |||||
|
P28069 | POU class 1 homeobox 1 | 4 | 0.548 | 0.654 | 4.5E-02 | 0.320 | strong | 1.000 | 1 | 0 | 1995 | 2005 | |||||
|
Q53HL2 | cell division cycle associated 8 | 3 | 0.659 | 0.500 | 7.2E-03 | 0.300 | moderate | 1.000 | 1 | 0 | 2018 | 2018 |