Source: BEFREE ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 2245 0.236 0.962 0.53 0.500 None 0.933 13 0 1996 2017
Entrez Id: 4851
Gene Symbol: NOTCH1
NOTCH1 		P46531 notch receptor 1 581 0.369 0.885 1.00 0.440 None 1.000 4 0 2013 2018
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1277 0.292 0.923 1.00 0.420 None 1.000 2 0 2013 2019
Entrez Id: 4602
Gene Symbol: MYB
MYB 		P10242 MYB proto-oncogene, transcription factor 196 0.490 0.692 0.82 0.400 None 0.963 53 0 2009 2019
Entrez Id: 4781
Gene Symbol: NFIB
NFIB 		O00712 nuclear factor I B Nucleic acid binding 83 0.573 0.654 1.00 0.400 None 1.000 33 0 2009 2019
Entrez Id: 4603
Gene Symbol: MYBL1
MYBL1 		P10243 MYB proto-oncogene like 1 19 0.705 0.308 1.00 0.400 None 1.000 10 0 2013 2019
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		P12830 cadherin 1 396 0.401 0.808 0.15 0.340 None 1.000 2 0 2002 2017
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		P60484 phosphatase and tensin homolog Enzyme 983 0.305 0.923 0.26 0.330 None 1.000 3 0 2010 2019
Entrez Id: 595
Gene Symbol: CCND1
CCND1 		P24385 cyclin D1 Enzyme modulator 748 0.344 0.923 0.89 0.330 None 1.000 2 0 2000 2006
Entrez Id: 472
Gene Symbol: ATM
ATM 		Q13315 ATM serine/threonine kinase Kinase 563 0.374 0.885 5.6E-47 0.310 None 1.000 1 0 2013 2018
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1 		P38398 BRCA1 DNA repair associated Enzyme 576 0.367 0.923 9.2E-29 0.310 None 1.000 1 0 2012 2013
Entrez Id: 358
Gene Symbol: AQP1
AQP1 		P29972 aquaporin 1 (Colton blood group) Ion channel 226 0.467 0.885 2.6E-07 0.310 None 1.000 1 0 2006 2014
Entrez Id: 3485
Gene Symbol: IGFBP2
IGFBP2 		P18065 insulin like growth factor binding protein 2 Enzyme modulator 223 0.478 0.769 0.12 0.310 None 1.000 1 0 2006 2018
Entrez Id: 1612
Gene Symbol: DAPK1
DAPK1 		P53355 death associated protein kinase 1 Kinase 211 0.472 0.808 1.00 0.310 None 1.000 1 0 2005 2006
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		P01116 KRAS proto-oncogene, GTPase Enzyme modulator 805 0.320 0.923 7.9E-04 0.110 None 1.000 1 1 2009 2009
Entrez Id: 3815
Gene Symbol: KIT
KIT 		P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 627 0.366 0.808 0.98 0.100 None 1.000 12 0 1999 2019
Entrez Id: 1540
Gene Symbol: CYLD
CYLD 		Q9NQC7 CYLD lysine 63 deubiquitinase Enzyme 192 0.498 0.846 1.00 0.100 None 0.900 10 2 1996 2018
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		P00533 epidermal growth factor receptor Kinase 1308 0.295 0.885 0.37 0.080 None 1.000 8 0 1996 2018
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		P42771 Q8N726 cyclin dependent kinase inhibitor 2A 1214 0.300 0.885 0.39 0.070 None 1.000 6 0 2000 2017
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		P35222 catenin beta 1 1156 0.303 0.885 1.00 0.070 None 1.000 6 0 2004 2019
Entrez Id: 6663
Gene Symbol: SOX10
SOX10 		P56693 SRY-box transcription factor 10 215 0.461 0.808 0.99 0.060 None 1.000 6 0 2016 2019
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		P04626 erb-b2 receptor tyrosine kinase 2 Kinase 942 0.328 0.923 6.0E-03 0.050 None 0.800 5 0 1996 2013
Entrez Id: 7852
Gene Symbol: CXCR4
CXCR4 		P61073 C-X-C motif chemokine receptor 4 G-protein coupled receptor 681 0.362 0.923 1.8E-02 0.050 None 1.000 5 0 2008 2017
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A 		Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 953 0.327 0.923 0.98 0.040 None 1.000 4 0 2014 2019
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		P15692 vascular endothelial growth factor A Signaling 1737 0.266 0.923 2.4E-05 0.040 None 1.000 4 0 2014 2019