Source: BEFREE ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1080
Gene Symbol: CFTR
CFTR 		P13569 CF transmembrane conductance regulator Ion channel 365 0.424 0.885 2.2E-58 1.000 None 0.979 1864 104 1989 2020
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1 		P01137 transforming growth factor beta 1 Signaling 1334 0.287 0.962 3.7E-02 0.700 moderate 0.952 19 3 2000 2019
Entrez Id: 6338
Gene Symbol: SCNN1B
SCNN1B 		P51168 sodium channel epithelial 1 subunit beta Ion channel 27 0.628 0.577 5.8E-08 0.600 None 1.000 15 0 2005 2019
Entrez Id: 51164
Gene Symbol: DCTN4
DCTN4 		Q9UJW0 dynactin subunit 4 240 0.472 0.846 0.73 0.540 None 1.000 4 1 2012 2019
Entrez Id: 6337
Gene Symbol: SCNN1A
SCNN1A 		P37088 sodium channel epithelial 1 subunit alpha Ion channel 35 0.601 0.577 1.1E-11 0.390 None 0.909 8 1 2004 2017
Entrez Id: 6340
Gene Symbol: SCNN1G
SCNN1G 		P51170 sodium channel epithelial 1 subunit gamma Ion channel 25 0.633 0.577 0.48 0.370 None 1.000 6 1 2006 2019
Entrez Id: 22802
Gene Symbol: CLCA4
CLCA4 		Q14CN2 chloride channel accessory 4 Ion channel 19 0.729 0.385 7.0E-15 0.340 None 1.000 3 0 2004 2015
Entrez Id: 6804
Gene Symbol: STX1A
STX1A 		Q16623 syntaxin 1A Transporter 61 0.621 0.654 0.98 0.310 None 1.000 1 2 2013 2013
Entrez Id: 7132
Gene Symbol: TNFRSF1A
TNFRSF1A 		P19438 TNF receptor superfamily member 1A 390 0.409 0.923 0.99 0.310 None 1.000 1 0 2006 2006
Entrez Id: 5644
Gene Symbol: PRSS1
PRSS1 		P07477 serine protease 1 Enzyme 79 0.563 0.692 4.1E-11 0.240 None 1.000 4 0 1996 2019
Entrez Id: 4583
Gene Symbol: MUC2
MUC2 		Q02817 mucin 2, oligomeric mucus/gel-forming Enzyme modulator 195 0.486 0.808 9.4E-10 0.230 None 1.000 3 0 1997 2006
Entrez Id: 1181
Gene Symbol: CLCN2
CLCN2 		P51788 chloride voltage-gated channel 2 Ion channel 43 0.626 0.462 5.5E-12 0.230 None 1.000 3 0 1996 2004
Entrez Id: 4153
Gene Symbol: MBL2
MBL2 		P11226 mannose binding lectin 2 Receptor 542 0.390 0.846 2.7E-03 0.200 None 0.913 23 1 1999 2019
Entrez Id: 5265
Gene Symbol: SERPINA1
SERPINA1 		P01009 serpin family A member 1 Enzyme modulator 411 0.410 0.923 6.8E-08 0.200 None 0.957 22 0 1991 2019
Entrez Id: 6550
Gene Symbol: SLC9A3
SLC9A3 		P48764 solute carrier family 9 member A3 Transporter 58 0.612 0.615 0.98 0.190 None 1.000 9 0 2006 2018
Entrez Id: 3077
Gene Symbol: HFE
HFE 		Q30201 homeostatic iron regulator 310 0.436 0.846 2.6E-08 0.160 None 1.000 6 2 1998 2019
Entrez Id: 4585
Gene Symbol: MUC4
MUC4 		Q99102 mucin 4, cell surface associated 155 0.506 0.769 2.8E-54 0.120 None 1.000 1 0 2007 2015
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8 		P10145 C-X-C motif chemokine ligand 8 Signaling 1173 0.310 0.962 2.7E-04 0.100 None 0.962 76 3 1992 2019
Entrez Id: 7124
Gene Symbol: TNF
TNF 		P01375 tumor necrosis factor Signaling 2475 0.231 0.962 0.80 0.100 None 0.970 33 0 1993 2019
Entrez Id: 1991
Gene Symbol: ELANE
ELANE 		P08246 elastase, neutrophil expressed Enzyme 290 0.447 0.846 1.2E-03 0.100 None 0.962 26 0 1992 2019
Entrez Id: 54498
Gene Symbol: SMOX
SMOX 		Q9NWM0 spermine oxidase 68 0.603 0.769 0.40 0.100 None 0.880 25 0 1990 2019
Entrez Id: 4233
Gene Symbol: MET
MET 		P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 501 0.380 0.846 0.97 0.100 None 1.000 18 0 1986 1990
Entrez Id: 3553
Gene Symbol: IL1B
IL1B 		P01584 interleukin 1 beta 1604 0.276 0.962 0.13 0.100 None 1.000 18 2 1996 2019
Entrez Id: 54738
Gene Symbol: FEV
FEV 		Q99581 FEV transcription factor, ETS family member Transcription factor 83 0.593 0.692 8.1E-03 0.100 None 0.875 16 0 2000 2018
Entrez Id: 55107
Gene Symbol: ANO1
ANO1 		Q5XXA6 anoctamin 1 Ion channel 171 0.516 0.769 0.87 0.100 None 1.000 15 0 2011 2020