Source: BEFREE ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 9968
Gene Symbol: MED12
MED12 		Q93074 mediator complex subunit 12 Transcription factor 124 0.476 0.769 1.00 0.400 None 1.000 18 0 2015 2018
Entrez Id: 8085
Gene Symbol: KMT2D
KMT2D 		O14686 lysine methyltransferase 2D 189 0.465 0.808 1.00 0.310 None 1.000 1 0 2015 2015
Entrez Id: 5914
Gene Symbol: RARA
RARA 		P10276 retinoic acid receptor alpha Nuclear receptor 225 0.470 0.846 0.96 0.310 None 1.000 1 0 2015 2015
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 2245 0.236 0.962 0.53 0.080 None 0.875 8 0 1998 2017
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		P00533 epidermal growth factor receptor Kinase 1308 0.295 0.885 0.37 0.080 None 0.875 8 0 2000 2016
Entrez Id: 3815
Gene Symbol: KIT
KIT 		P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 627 0.366 0.808 0.98 0.070 None 0.857 6 0 2000 2015
Entrez Id: 110806263
Gene Symbol: LOC110806263
LOC110806263 		TERT 5' regulatory region 245 0.464 0.731 0.060 None 1.000 6 0 2015 2019
Entrez Id: 7015
Gene Symbol: TERT
TERT 		O14746 telomerase reverse transcriptase Enzyme 525 0.374 0.846 0.99 0.040 None 1.000 4 0 2016 2018
Entrez Id: 2099
Gene Symbol: ESR1
ESR1 		P03372 estrogen receptor 1 Nuclear receptor 972 0.324 0.962 1.00 0.030 None 1.000 3 0 2001 2016
Entrez Id: 7405
Gene Symbol: UVRAG
UVRAG 		Q9P2Y5 UV radiation resistance associated 334 0.436 0.769 0.99 0.020 None 0.500 2 0 2004 2018
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1277 0.292 0.923 1.00 0.020 None 1.000 2 0 2013 2019
Entrez Id: 7291
Gene Symbol: TWIST1
TWIST1 		Q15672 twist family bHLH transcription factor 1 Transcription factor 436 0.397 0.846 0.34 0.020 None 1.000 2 0 2010 2013
Entrez Id: 6121
Gene Symbol: RPE65
RPE65 		Q16518 retinoid isomerohydrolase RPE65 Enzyme 379 0.417 0.808 6.5E-14 0.020 None 0.500 2 0 2004 2018
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG 		P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1087 0.320 0.885 1.4E-06 0.020 None 1.000 2 0 2013 2019
Entrez Id: 4313
Gene Symbol: MMP2
MMP2 		P08253 matrix metallopeptidase 2 Enzyme 826 0.333 0.923 0.84 0.020 None 1.000 2 0 1993 2017
Entrez Id: 367
Gene Symbol: AR
AR 		P10275 androgen receptor Nuclear receptor 762 0.351 0.846 0.99 0.020 None 1.000 2 0 1997 2007
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1105 0.319 0.885 1.00 0.020 None 1.000 2 0 2013 2019
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB 		P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1077 0.322 0.885 1.00 0.020 None 1.000 2 0 2013 2019
Entrez Id: 5156
Gene Symbol: PDGFRA
PDGFRA 		P16234 platelet derived growth factor receptor alpha Kinase 383 0.415 0.808 1.00 0.020 None 0.500 2 0 2004 2010
Entrez Id: 406991
Gene Symbol: MIR21
MIR21 		microRNA 21 705 0.363 0.846 0.020 None 1.000 2 0 2014 2015
Entrez Id: 4193
Gene Symbol: MDM2
MDM2 		Q00987 MDM2 proto-oncogene Nucleic acid binding 669 0.362 0.846 1.00 0.020 None 1.000 2 0 2007 2016
Entrez Id: 80331
Gene Symbol: DNAJC5
DNAJC5 		Q9H3Z4 DnaJ heat shock protein family (Hsp40) member C5 38 0.653 0.500 0.81 0.020 None 1.000 2 0 2013 2020
Entrez Id: 1827
Gene Symbol: RCAN1
RCAN1 		P53805 regulator of calcineurin 1 Signaling 100 0.572 0.808 1.7E-02 0.020 None 1.000 2 0 2017 2018
Entrez Id: 11186
Gene Symbol: RASSF1
RASSF1 		Q9NS23 Ras association domain family member 1 Enzyme modulator 378 0.420 0.808 4.9E-06 0.020 None 1.000 2 0 2009 2010
Entrez Id: 10970
Gene Symbol: CKAP4
CKAP4 		Q07065 cytoskeleton associated protein 4 332 0.436 0.731 0.51 0.020 None 0.500 2 0 2004 2018