Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7099
Gene Symbol: TLR4
TLR4 		O00206 toll like receptor 4 1174 0.321 0.962 4.6E-09 0.090 None 0.889 9 3 2004 2020
Entrez Id: 6347
Gene Symbol: CCL2
CCL2 		P13500 C-C motif chemokine ligand 2 Signaling 1157 0.321 0.962 0.61 0.070 None 1.000 7 0 2001 2019
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB 		P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1083 0.322 0.885 1.00 0.080 None 1.000 8 0 2016 2020
Entrez Id: 3605
Gene Symbol: IL17A
IL17A 		Q16552 interleukin 17A 1074 0.324 0.923 4.3E-02 0.100 None 1.000 16 0 2010 2019
Entrez Id: 29126
Gene Symbol: CD274
CD274 		Q9NZQ7 CD274 molecule Receptor 1011 0.324 0.923 1.9E-02 0.100 None 1.000 14 2 2010 2019
Entrez Id: 2099
Gene Symbol: ESR1
ESR1 		P03372 estrogen receptor 1 Nuclear receptor 1101 0.324 0.962 1.00 0.070 None 1.000 7 0 2011 2018
Entrez Id: 60
Gene Symbol: ACTB
ACTB 		P60709 actin beta Cellular structure 1110 0.325 0.923 0.99 0.040 None 1.000 4 0 2002 2018
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A 		Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 1044 0.327 0.923 0.98 0.070 None 1.000 7 0 2016 2020
Entrez Id: 1636
Gene Symbol: ACE
ACE 		P12821 angiotensin I converting enzyme Enzyme 1082 0.328 0.923 1.0E-37 0.100 None 0.933 60 2 1994 2019
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1 		P28482 mitogen-activated protein kinase 1 Kinase 1059 0.330 0.923 1.00 0.030 None 1.000 3 0 2002 2016
Entrez Id: 1437
Gene Symbol: CSF2
CSF2 		P04141 colony stimulating factor 2 Signaling 1028 0.330 0.962 0.83 0.020 None 1.000 2 0 2013 2017
Entrez Id: 3565
Gene Symbol: IL4
IL4 		P05112 interleukin 4 996 0.332 0.962 4.7E-03 0.300 None 0.919 37 1 1996 2019
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1 		P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1018 0.333 0.923 1.1E-03 0.500 None 0.946 279 6 1988 2020
Entrez Id: 3552
Gene Symbol: IL1A
IL1A 		P01583 interleukin 1 alpha 1002 0.333 0.962 1.6E-04 0.100 None 0.929 14 1 1994 2018
Entrez Id: 4313
Gene Symbol: MMP2
MMP2 		P08253 matrix metallopeptidase 2 Enzyme 1021 0.333 0.923 0.84 0.160 None 1.000 6 0 2002 2019
Entrez Id: 3558
Gene Symbol: IL2
IL2 		P60568 interleukin 2 950 0.336 0.885 0.48 0.100 None 1.000 53 2 1984 2020
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		P42898 methylenetetrahydrofolate reductase 985 0.337 0.885 3.2E-10 0.040 None 0.750 4 2 1999 2008
Entrez Id: 348
Gene Symbol: APOE
APOE 		P02649 apolipoprotein E 1049 0.338 0.962 1.9E-03 0.100 None 1.000 14 0 1991 2018
Entrez Id: 2475
Gene Symbol: MTOR
MTOR 		P42345 mechanistic target of rapamycin kinase Kinase 960 0.343 0.885 1.00 0.030 None 1.000 3 0 2018 2019
Entrez Id: 4609
Gene Symbol: MYC
MYC 		P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 821 0.344 0.923 1.00 0.010 None 1.000 1 0 2007 2007
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1 		P08183 ATP binding cassette subfamily B member 1 Transporter 933 0.344 0.885 1.3E-05 0.010 None 1.000 1 0 2012 2012
Entrez Id: 627
Gene Symbol: BDNF
BDNF 		P23560 brain derived neurotrophic factor Signaling 992 0.345 0.923 0.66 0.030 None 1.000 3 0 2010 2019
Entrez Id: 3952
Gene Symbol: LEP
LEP 		P41159 leptin 931 0.349 0.846 0.46 0.100 None 1.000 25 0 2000 2020
Entrez Id: 836
Gene Symbol: CASP3
CASP3 		P42574 caspase 3 Enzyme 819 0.351 0.923 0.10 0.290 None 1.000 10 0 2005 2019
Entrez Id: 367
Gene Symbol: AR
AR 		P10275 androgen receptor Nuclear receptor 854 0.351 0.846 0.99 0.010 None 1.000 1 0 2003 2003