Source: INFERRED ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		P00533 epidermal growth factor receptor Kinase 45 0.295 0.885 0.37 0.700 None 0.975 4 10 1988 2020
Entrez Id: 2475
Gene Symbol: MTOR
MTOR 		P42345 mechanistic target of rapamycin kinase Kinase 153 0.343 0.885 1.00 0.500 None 0.967 1 5 2005 2019
Entrez Id: 3020
Gene Symbol: H3-3A
H3-3A 		P84243 H3.3 histone A 68 0.559 0.692 0.12 0.500 None 0.955 1 1 2012 2018
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		P60484 phosphatase and tensin homolog Enzyme 341 0.305 0.923 0.26 0.500 None 0.977 1 2 1997 2020
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 221 0.236 0.962 0.53 0.400 None 0.976 4 50 1990 2019
Entrez Id: 4613
Gene Symbol: MYCN
MYCN 		P04198 MYCN proto-oncogene, bHLH transcription factor Transcription factor 53 0.454 0.808 0.89 0.200 None 1.000 1 1 1988 2019
Entrez Id: 3417
Gene Symbol: IDH1
IDH1 		O75874 isocitrate dehydrogenase (NADP(+)) 1 55 0.424 0.808 2.6E-12 0.200 None 0.975 1 2 2008 2020
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 283 0.292 0.923 1.00 0.200 None 0.944 1 29 2000 2020
Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1 		P11362 fibroblast growth factor receptor 1 Kinase 330 0.362 0.885 1.00 0.200 None 0.882 1 2 1994 2019
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 342 0.319 0.846 1.00 0.200 None 1.000 1 3 2004 2019
Entrez Id: 472
Gene Symbol: ATM
ATM 		Q13315 ATM serine/threonine kinase Kinase 120 0.374 0.885 5.6E-47 0.200 None 1.000 0 1 2000 2019
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		P43246 mutS homolog 2 Nucleic acid binding 97 0.406 0.808 0.90 0.190 None 1.000 0 1 2003 2019
Entrez Id: 51750
Gene Symbol: RTEL1
RTEL1 		Q9NZ71 regulator of telomere elongation helicase 1 Enzyme 124 0.459 0.808 8.9E-10 0.170 None 1.000 3 2 2010 2020
Entrez Id: 137196
Gene Symbol: CCDC26
CCDC26 		Q8TAB7 CCDC26 long non-coding RNA 32 0.647 0.615 0.140 None 1.000 2 1 2010 2018
Entrez Id: 5295
Gene Symbol: PIK3R1
PIK3R1 		P27986 phosphoinositide-3-kinase regulatory subunit 1 Kinase 119 0.477 0.885 1.00 0.140 None 0.800 1 1 2004 2016
Entrez Id: 4893
Gene Symbol: NRAS
NRAS 		P01111 NRAS proto-oncogene, GTPase Enzyme modulator 216 0.390 0.808 0.49 0.140 None 1.000 1 2 1996 2016
Entrez Id: 5395
Gene Symbol: PMS2
PMS2 		P54278 PMS1 homolog 2, mismatch repair system component Nucleic acid binding 95 0.484 0.808 4.5E-27 0.140 None 1.000 0 1 2007 2017
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7 		Q969H0 F-box and WD repeat domain containing 7 Enzyme modulator 22 0.465 0.808 1.00 0.130 None 1.000 1 3 2005 2018
Entrez Id: 3265
Gene Symbol: HRAS
HRAS 		P01112 HRas proto-oncogene, GTPase Enzyme modulator 229 0.378 0.885 8.0E-02 0.130 None 1.000 1 2 1987 2016
Entrez Id: 5426
Gene Symbol: POLE
POLE 		Q07864 DNA polymerase epsilon, catalytic subunit 58 0.526 0.731 8.0E-27 0.130 None 1.000 1 1 2016 2019
Entrez Id: 23635
Gene Symbol: SSBP2
SSBP2 		P81877 single stranded DNA binding protein 2 7 0.659 0.269 1.00 0.120 None 1.000 1 1 2012 2018
Entrez Id: 1788
Gene Symbol: DNMT3A
DNMT3A 		Q9Y6K1 DNA methyltransferase 3 alpha 85 0.445 0.846 7.4E-39 0.120 None 1.000 0 1 2008 2015
Entrez Id: 100048912
Gene Symbol: CDKN2B-AS1
CDKN2B-AS1 		CDKN2B antisense RNA 1 79 0.491 0.769 0.110 None 1.000 3 2 2015 2018
Entrez Id: 55703
Gene Symbol: POLR3B
POLR3B 		Q9NW08 RNA polymerase III subunit B Enzyme 53 0.628 0.654 1.7E-23 0.110 None 1.000 1 1 2015 2015
Entrez Id: 100533107
Gene Symbol: RTEL1-TNFRSF6B
RTEL1-TNFRSF6B 		RTEL1-TNFRSF6B readthrough (NMD candidate) 32 0.682 0.385 0.100 None 1.000 3 2 2015 2018