Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
P01116 KRAS proto-oncogene, GTPase enzyme modulator 886 0.350 0.724 9.0E-04 0.640 1.000 9 1 1994 2016
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 transcription factor 1773 0.251 0.897 0.17 0.600 0.857 18 1 1994 2016
Entrez Id: 3791
Gene Symbol: KDR
KDR
P35968 kinase insert domain receptor 343 0.423 0.724 1.00 0.550 1.000 6 0 2008 2016
Entrez Id: 5335
Gene Symbol: PLCG1
PLCG1
P19174 phospholipase C gamma 1 calcium-binding protein; enzyme modulator; hydrolase; signaling molecule 62 0.611 0.517 1.8E-04 0.540 1.000 4 0 2014 2016
Entrez Id: 5787
Gene Symbol: PTPRB
PTPRB
P23467 protein tyrosine phosphatase, receptor type B 7 0.928 0.034 0.81 0.530 1.000 3 0 2014 2016
Entrez Id: 4609
Gene Symbol: MYC
MYC
P01106 MYC proto-oncogene, bHLH transcription factor nucleic acid binding; transcription factor 499 0.382 0.724 1.00 0.400 0.941 18 0 2008 2016
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
P15692 vascular endothelial growth factor A signaling molecule 1174 0.298 0.897 2.7E-05 0.350 1.000 6 0 1996 2012
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
P01112 HRas proto-oncogene, GTPase enzyme modulator 545 0.404 0.828 8.7E-02 0.330 1.000 4 0 1998 2016
Entrez Id: 2701
Gene Symbol: GJA4
GJA4
P35212 gap junction protein alpha 4 cell junction protein 23 0.701 0.276 4.5E-02 0.320 1.000 3 1 2000 2010
Entrez Id: 7010
Gene Symbol: TEK
TEK
Q02763 TEK receptor tyrosine kinase 169 0.511 0.655 1.00 0.310 < 0.001 2 0 2004 2008
Entrez Id: 595
Gene Symbol: CCND1
CCND1
P24385 cyclin D1 enzyme modulator 589 0.365 0.828 0.90 0.300 1 0 2008 2008
Entrez Id: 2321
Gene Symbol: FLT1
FLT1
P17948 fms related tyrosine kinase 1 259 0.453 0.793 1.00 0.300 1 0 2008 2008
Entrez Id: 80781
Gene Symbol: COL18A1
COL18A1
P39060 collagen type XVIII alpha 1 chain 188 0.489 0.759 1.5E-09 0.300 1 0 2008 2008
Entrez Id: 7424
Gene Symbol: VEGFC
VEGFC
P49767 vascular endothelial growth factor C signaling molecule 168 0.501 0.690 0.51 0.300 1 0 2008 2008
Entrez Id: 3725
Gene Symbol: JUN
JUN
P05412 Jun proto-oncogene, AP-1 transcription factor subunit nucleic acid binding; transcription factor 213 0.473 0.828 0.65 0.300 1 0 2008 2008
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
P35222 catenin beta 1 412 0.417 0.759 1.00 0.300 1 0 2003 2003
Entrez Id: 1440
Gene Symbol: CSF3
CSF3
P09919 colony stimulating factor 3 393 0.421 0.828 0.33 0.300 1 0 1998 1998
Entrez Id: 285
Gene Symbol: ANGPT2
ANGPT2
O15123 angiopoietin 2 signaling molecule 211 0.479 0.724 0.86 0.300 1 0 2008 2008
Entrez Id: 3815
Gene Symbol: KIT
KIT
P10721 KIT proto-oncogene receptor tyrosine kinase 462 0.394 0.759 0.99 0.040 1.000 4 0 2000 2014
Entrez Id: 2324
Gene Symbol: FLT4
FLT4
P35916 fms related tyrosine kinase 4 153 0.510 0.724 1.00 0.040 0.750 4 0 2011 2016
Entrez Id: 4193
Gene Symbol: MDM2
MDM2
Q00987 MDM2 proto-oncogene nucleic acid binding 436 0.396 0.759 1.00 0.030 0.667 3 0 1994 2014
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 891 0.321 0.828 0.38 0.030 1.000 3 0 2002 2014
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog hydrolase; phosphatase 915 0.334 0.828 0.82 0.030 1.000 3 0 2007 2014
Entrez Id: 673
Gene Symbol: BRAF
BRAF
P15056 B-Raf proto-oncogene, serine/threonine kinase 871 0.352 0.793 1.00 0.020 1.000 2 0 2016 2018
Entrez Id: 5629
Gene Symbol: PROX1
PROX1
Q92786 prospero homeobox 1 nucleic acid binding; transcription factor 75 0.596 0.448 1.00 0.020 0.500 2 0 2012 2012