Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3064
Gene Symbol: HTT
HTT
P42858 huntingtin 122 0.548 0.654 1.00 1.000 limited 0.987 1271 3 1993 2020
Entrez Id: 4968
Gene Symbol: OGG1
OGG1
O15527 8-oxoguanine DNA glycosylase 266 0.453 0.808 3.9E-12 0.360 None 1.000 6 1 2007 2013
Entrez Id: 1268
Gene Symbol: CNR1
CNR1
P21554 cannabinoid receptor 1 G-protein coupled receptor 287 0.446 0.808 0.51 0.360 None 1.000 6 0 2009 2019
Entrez Id: 2668
Gene Symbol: GDNF
GDNF
P39905 glial cell derived neurotrophic factor Signaling 296 0.434 0.885 0.20 0.340 None 1.000 3 0 2005 2016
Entrez Id: 6515
Gene Symbol: SLC2A3
SLC2A3
P11169 solute carrier family 2 member 3 Transporter 115 0.534 0.769 1.0E-02 0.330 None 1.000 3 0 2014 2018
Entrez Id: 4128
Gene Symbol: MAOA
MAOA
P21397 monoamine oxidase A 267 0.465 0.769 1.00 0.320 None 1.000 2 0 2011 2016
Entrez Id: 2166
Gene Symbol: FAAH
FAAH
O00519 fatty acid amide hydrolase 139 0.545 0.692 4.4E-11 0.320 None 1.000 2 0 2007 2018
Entrez Id: 9131
Gene Symbol: AIFM1
AIFM1
O95831 apoptosis inducing factor mitochondria associated 1 Enzyme 86 0.527 0.769 1.00 0.320 None 1.000 2 0 2003 2012
Entrez Id: 2030
Gene Symbol: SLC29A1
SLC29A1
Q99808 solute carrier family 29 member 1 (Augustine blood group) Transporter 72 0.587 0.731 0.90 0.320 None 1.000 2 0 2016 2017
Entrez Id: 1827
Gene Symbol: RCAN1
RCAN1
P53805 regulator of calcineurin 1 Signaling 100 0.572 0.808 1.7E-02 0.310 None 1.000 1 0 2009 2009
Entrez Id: 10891
Gene Symbol: PPARGC1A
PPARGC1A
Q9UBK2 PPARG coactivator 1 alpha Transcription factor 294 0.453 0.885 1.00 0.300 None 0.966 27 1 2006 2019
Entrez Id: 84152
Gene Symbol: PPP1R1B
PPP1R1B
Q9UD71 protein phosphatase 1 regulatory inhibitor subunit 1B Enzyme modulator 63 0.617 0.500 0.24 0.300 None 1.000 13 0 2004 2019
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
Q16236 nuclear factor, erythroid 2 like 2 Enzyme 739 0.357 0.885 3.6E-03 0.300 None 1.000 12 0 2010 2019
Entrez Id: 1270
Gene Symbol: CNTF
CNTF
P26441 ciliary neurotrophic factor 105 0.561 0.615 2.3E-05 0.300 None 0.846 12 0 1997 2008
Entrez Id: 1385
Gene Symbol: CREB1
CREB1
P16220 cAMP responsive element binding protein 1 269 0.463 0.885 1.00 0.270 None 1.000 7 0 2006 2018
Entrez Id: 23390
Gene Symbol: ZDHHC17
ZDHHC17
Q8IUH5 zinc finger DHHC-type palmitoyltransferase 17 5 0.890 0.269 1.00 0.270 None 0.875 7 0 2002 2017
Entrez Id: 3952
Gene Symbol: LEP
LEP
P41159 leptin 807 0.349 0.846 0.46 0.250 None 1.000 4 0 2004 2019
Entrez Id: 4852
Gene Symbol: NPY
NPY
P01303 neuropeptide Y Signaling 289 0.447 0.846 0.14 0.250 None 1.000 4 0 1991 2018
Entrez Id: 3708
Gene Symbol: ITPR1
ITPR1
Q14643 inositol 1,4,5-trisphosphate receptor type 1 Ion channel 109 0.534 0.846 1.00 0.240 None 1.000 4 0 1998 2014
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
P14780 matrix metallopeptidase 9 Enzyme 1160 0.305 0.923 1.9E-17 0.230 None 1.000 3 0 1998 2017
Entrez Id: 5467
Gene Symbol: PPARD
PPARD
Q03181 peroxisome proliferator activated receptor delta Nuclear receptor 167 0.513 0.846 0.99 0.230 None 1.000 3 0 2016 2020
Entrez Id: 54503
Gene Symbol: ZDHHC13
ZDHHC13
Q8IUH4 zinc finger DHHC-type palmitoyltransferase 13 9 0.729 0.346 1.2E-19 0.220 None 1.000 2 0 2012 2015
Entrez Id: 1269
Gene Symbol: CNR2
CNR2
P34972 cannabinoid receptor 2 G-protein coupled receptor 166 0.509 0.846 6.5E-06 0.220 None 1.000 2 0 2009 2011
Entrez Id: 596
Gene Symbol: BCL2
BCL2
P10415 BCL2 apoptosis regulator Signaling 1294 0.291 0.885 0.56 0.220 None 1.000 2 0 1999 2015
Entrez Id: 1812
Gene Symbol: DRD1
DRD1
P21728 dopamine receptor D1 G-protein coupled receptor 129 0.529 0.808 0.96 0.210 None 1.000 1 0 1994 2008