Source: BEFREE ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1080
Gene Symbol: CFTR
CFTR 		P13569 CF transmembrane conductance regulator Ion channel 365 0.424 0.885 2.2E-58 0.500 None 1.000 32 0 1995 2020
Entrez Id: 2516
Gene Symbol: NR5A1
NR5A1 		Q13285 nuclear receptor subfamily 5 group A member 1 Nuclear receptor 173 0.479 0.731 0.99 0.450 None 0.800 5 0 2010 2018
Entrez Id: 6795
Gene Symbol: AURKC
AURKC 		Q9UQB9 aurora kinase C Kinase 18 0.736 0.308 7.8E-02 0.430 None 1.000 3 0 2007 2019
Entrez Id: 2488
Gene Symbol: FSHB
FSHB 		P01225 follicle stimulating hormone subunit beta Signaling 25 0.631 0.577 0.34 0.420 None 1.000 2 0 1979 2017
Entrez Id: 367
Gene Symbol: AR
AR 		P10275 androgen receptor Nuclear receptor 762 0.351 0.846 0.99 0.400 None 0.918 47 4 1995 2019
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		P42898 methylenetetrahydrofolate reductase 816 0.337 0.885 3.2E-10 0.400 None 0.872 39 5 2003 2019
Entrez Id: 2099
Gene Symbol: ESR1
ESR1 		P03372 estrogen receptor 1 Nuclear receptor 972 0.324 0.962 1.00 0.400 None 0.929 12 2 2002 2019
Entrez Id: 1543
Gene Symbol: CYP1A1
CYP1A1 		P04798 cytochrome P450 family 1 subfamily A member 1 Enzyme 323 0.436 0.846 1.1E-17 0.400 None 1.000 10 2 2008 2019
Entrez Id: 4846
Gene Symbol: NOS3
NOS3 		P29474 nitric oxide synthase 3 559 0.378 0.885 6.7E-07 0.370 None 0.857 7 1 2008 2018
Entrez Id: 5428
Gene Symbol: POLG
POLG 		P54098 DNA polymerase gamma, catalytic subunit Enzyme 167 0.457 0.846 2.1E-09 0.370 None 0.625 7 0 2004 2013
Entrez Id: 4548
Gene Symbol: MTR
MTR 		Q99707 5-methyltetrahydrofolate-homocysteine methyltransferase 196 0.482 0.808 2.4E-12 0.360 None 0.833 6 1 2006 2017
Entrez Id: 4552
Gene Symbol: MTRR
MTRR 		Q9UBK8 5-methyltetrahydrofolate-homocysteine methyltransferase reductase 159 0.502 0.808 2.2E-14 0.360 None 0.714 6 1 2006 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 2245 0.236 0.962 0.53 0.360 None 0.833 6 4 2007 2018
Entrez Id: 196
Gene Symbol: AHR
AHR 		P35869 aryl hydrocarbon receptor Transcription factor 428 0.410 0.923 1.00 0.340 None 1.000 4 2 2004 2019
Entrez Id: 1636
Gene Symbol: ACE
ACE 		P12821 angiotensin I converting enzyme Enzyme 979 0.328 0.923 1.0E-37 0.330 None 0.750 3 0 1996 2017
Entrez Id: 5444
Gene Symbol: PON1
PON1 		P27169 paraoxonase 1 387 0.409 0.885 9.8E-11 0.330 None 1.000 3 1 2011 2014
Entrez Id: 4968
Gene Symbol: OGG1
OGG1 		O15527 8-oxoguanine DNA glycosylase 266 0.453 0.808 3.9E-12 0.320 None 1.000 2 1 2013 2018
Entrez Id: 596
Gene Symbol: BCL2
BCL2 		P10415 BCL2 apoptosis regulator Signaling 1294 0.291 0.885 0.56 0.310 None 1.000 1 0 2014 2017
Entrez Id: 4193
Gene Symbol: MDM2
MDM2 		Q00987 MDM2 proto-oncogene Nucleic acid binding 669 0.362 0.846 1.00 0.310 None 1.000 1 1 2012 2012
Entrez Id: 1586
Gene Symbol: CYP17A1
CYP17A1 		P05093 cytochrome P450 family 17 subfamily A member 1 224 0.462 0.769 2.6E-04 0.310 None 1.000 1 1 2005 2014
Entrez Id: 84071
Gene Symbol: ARMC2
ARMC2 		Q8NEN0 armadillo repeat containing 2 3 0.805 0.115 2.5E-09 0.310 None 1.000 1 0 2019 2019
Entrez Id: 339345
Gene Symbol: NANOS2
NANOS2 		P60321 nanos C2HC-type zinc finger 2 37 0.678 0.462 5.2E-02 0.310 None 1.000 1 0 2012 2018
Entrez Id: 161582
Gene Symbol: DNAAF4
DNAAF4 		Q8WXU2 dynein axonemal assembly factor 4 22 0.623 0.731 9.7E-10 0.310 None 1.000 1 0 2013 2013
Entrez Id: 6648
Gene Symbol: SOD2
SOD2 		P04179 superoxide dismutase 2 Enzyme 450 0.379 0.923 0.15 0.310 None 1.000 1 1 2012 2012
Entrez Id: 83449
Gene Symbol: PMFBP1
PMFBP1 		Q8TBY8 polyamine modulated factor 1 binding protein 1 4 0.821 0.115 9.3E-34 0.310 None 1.000 1 0 2018 2018