Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3586
Gene Symbol: IL10
IL10
P22301 interleukin 10 1533 0.281 0.923 5.9E-03 0.700 None 0.993 135 3 1995 2020
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2475 0.231 0.962 0.80 0.600 None 0.964 360 1 1992 2020
Entrez Id: 64127
Gene Symbol: NOD2
NOD2
Q9HC29 nucleotide binding oligomerization domain containing 2 Enzyme 353 0.423 0.923 2.0E-30 0.500 None 0.949 185 21 1998 2020
Entrez Id: 149233
Gene Symbol: IL23R
IL23R
Q5VWK5 interleukin 23 receptor Signaling 208 0.466 0.769 5.6E-04 0.500 None 0.947 70 9 2006 2020
Entrez Id: 55054
Gene Symbol: ATG16L1
ATG16L1
Q676U5 autophagy related 16 like 1 102 0.543 0.769 0.96 0.500 None 0.974 35 3 2007 2020
Entrez Id: 9966
Gene Symbol: TNFSF15
TNFSF15
O95150 TNF superfamily member 15 Signaling 107 0.531 0.692 2.8E-03 0.500 None 0.971 33 4 2003 2020
Entrez Id: 345611
Gene Symbol: IRGM
IRGM
A1A4Y4 immunity related GTPase M 47 0.617 0.538 0.500 None 1.000 13 2 2008 2017
Entrez Id: 64170
Gene Symbol: CARD9
CARD9
Q9H257 caspase recruitment domain family member 9 80 0.566 0.654 8.1E-13 0.500 None 0.938 12 0 2009 2020
Entrez Id: 55765
Gene Symbol: INAVA
INAVA
Q3KP66 innate immunity activator 8 0.743 0.346 2.2E-04 0.420 None 1.000 2 1 2011 2018
Entrez Id: 8807
Gene Symbol: IL18RAP
IL18RAP
O95256 interleukin 18 receptor accessory protein Receptor 34 0.674 0.577 2.2E-03 0.410 None 1.000 1 1 2008 2015
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 2132 0.248 0.962 0.32 0.400 None 0.980 50 0 1992 2019
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
P40763 signal transducer and activator of transcription 3 Nucleic acid binding 999 0.320 0.923 1.00 0.400 None 0.972 32 0 2006 2019
Entrez Id: 3587
Gene Symbol: IL10RA
IL10RA
Q13651 interleukin 10 receptor subunit alpha Receptor 77 0.579 0.692 1.8E-02 0.400 strong 1.000 20 1 2012 2019
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
P05362 intercellular adhesion molecule 1 641 0.364 0.962 3.5E-02 0.400 None 1.000 18 3 1995 2019
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1043 0.314 0.962 1.00 0.400 None 1.000 17 0 1998 2019
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
P01137 transforming growth factor beta 1 Signaling 1334 0.287 0.962 3.7E-02 0.400 None 1.000 16 1 2001 2020
Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22
Q9Y2R2 protein tyrosine phosphatase non-receptor type 22 238 0.438 0.846 3.5E-21 0.400 None 0.714 13 1 2005 2019
Entrez Id: 331
Gene Symbol: XIAP
XIAP
P98170 X-linked inhibitor of apoptosis Enzyme modulator 281 0.447 0.808 0.92 0.400 strong 1.000 11 0 2012 2020
Entrez Id: 324
Gene Symbol: APC
APC
P25054 APC regulator of WNT signaling pathway 517 0.373 0.962 1.00 0.370 None 0.875 7 2 1997 2016
Entrez Id: 3588
Gene Symbol: IL10RB
IL10RB
Q08334 interleukin 10 receptor subunit beta Receptor 39 0.636 0.577 2.5E-06 0.360 strong 1.000 6 0 2011 2020
Entrez Id: 3559
Gene Symbol: IL2RA
IL2RA
P01589 interleukin 2 receptor subunit alpha Receptor 467 0.389 0.885 5.5E-02 0.350 None 1.000 5 0 2004 2015
Entrez Id: 6556
Gene Symbol: SLC11A1
SLC11A1
P49279 solute carrier family 11 member 1 Transporter 107 0.525 0.846 1.5E-19 0.350 None 0.667 5 2 1999 2010
Entrez Id: 9863
Gene Symbol: MAGI2
MAGI2
Q86UL8 membrane associated guanylate kinase, WW and PDZ domain containing 2 72 0.579 0.654 1.00 0.340 None 0.800 4 2 2009 2017
Entrez Id: 1670
Gene Symbol: DEFA5
DEFA5
Q01523 defensin alpha 5 27 0.695 0.423 5.2E-06 0.330 None 1.000 3 0 2008 2017
Entrez Id: 11186
Gene Symbol: RASSF1
RASSF1
Q9NS23 Ras association domain family member 1 Enzyme modulator 378 0.420 0.808 4.9E-06 0.320 None 1.000 2 0 2013 2019