Source: BEFREE ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 472
Gene Symbol: ATM
ATM 		Q13315 ATM serine/threonine kinase Kinase 563 0.374 0.885 5.6E-47 0.900 strong 1.000 14 0 1998 2018
Entrez Id: 2177
Gene Symbol: FANCD2
FANCD2 		Q9BXW9 FA complementation group D2 146 0.479 0.885 1.1E-30 0.620 strong 1.000 2 0 2005 2017
Entrez Id: 2188
Gene Symbol: FANCF
FANCF 		Q9NPI8 FA complementation group F 50 0.535 0.731 0.46 0.510 strong 1.000 1 0 2015 2017
Entrez Id: 4893
Gene Symbol: NRAS
NRAS 		P01111 NRAS proto-oncogene, GTPase Enzyme modulator 396 0.390 0.808 0.49 0.500 None 0.895 19 1 1987 2016
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 888 0.319 0.846 1.00 0.490 limited 1.000 9 3 1995 2018
Entrez Id: 4297
Gene Symbol: KMT2A
KMT2A 		Q03164 lysine methyltransferase 2A 314 0.410 0.885 1.00 0.400 None 0.997 375 0 1987 2020
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		P42771 Q8N726 cyclin dependent kinase inhibitor 2A 1214 0.300 0.885 0.39 0.400 None 0.958 47 1 1994 2016
Entrez Id: 3717
Gene Symbol: JAK2
JAK2 		O60674 Janus kinase 2 Kinase 514 0.385 0.885 0.65 0.400 None 0.947 35 2 1997 2019
Entrez Id: 7490
Gene Symbol: WT1
WT1 		P19544 WT1 transcription factor Nucleic acid binding 294 0.422 0.808 1.00 0.400 None 1.000 35 0 1992 2019
Entrez Id: 5781
Gene Symbol: PTPN11
PTPN11 		Q06124 protein tyrosine phosphatase non-receptor type 11 410 0.385 0.923 1.00 0.400 None 1.000 28 1 2003 2019
Entrez Id: 3558
Gene Symbol: IL2
IL2 		P60568 interleukin 2 894 0.336 0.885 0.48 0.400 None 1.000 26 0 1985 2019
Entrez Id: 6774
Gene Symbol: STAT3
STAT3 		P40763 signal transducer and activator of transcription 3 Nucleic acid binding 999 0.320 0.923 1.00 0.400 strong 0.962 25 1 2005 2019
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		P60484 phosphatase and tensin homolog Enzyme 983 0.305 0.923 0.26 0.400 None 1.000 22 1 1993 2019
Entrez Id: 1441
Gene Symbol: CSF3R
CSF3R 		Q99062 colony stimulating factor 3 receptor Signaling 110 0.550 0.692 1.5E-10 0.400 None 1.000 19 1 2001 2018
Entrez Id: 2078
Gene Symbol: ERG
ERG 		P11308 ETS transcription factor ERG Transcription factor 279 0.453 0.808 0.96 0.400 None 1.000 13 0 1994 2019
Entrez Id: 23532
Gene Symbol: PRAME
PRAME 		P78395 preferentially expressed antigen in melanoma 114 0.531 0.577 2.4E-07 0.400 None 1.000 13 0 1998 2018
Entrez Id: 595
Gene Symbol: CCND1
CCND1 		P24385 cyclin D1 Enzyme modulator 748 0.344 0.923 0.89 0.400 None 1.000 10 0 1992 2018
Entrez Id: 8743
Gene Symbol: TNFSF10
TNFSF10 		P50591 TNF superfamily member 10 Signaling 412 0.413 0.885 0.13 0.400 None 0.833 10 0 1998 2018
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1 		P09488 glutathione S-transferase mu 1 581 0.380 0.923 2.1E-03 0.400 None 0.846 8 0 1999 2019
Entrez Id: 29072
Gene Symbol: SETD2
SETD2 		Q9BYW2 SET domain containing 2, histone lysine methyltransferase Epigenetic regulator 353 0.424 0.846 1.00 0.390 None 1.000 9 0 2014 2019
Entrez Id: 2099
Gene Symbol: ESR1
ESR1 		P03372 estrogen receptor 1 Nuclear receptor 972 0.324 0.962 1.00 0.370 None 1.000 7 5 1991 2018
Entrez Id: 7153
Gene Symbol: TOP2A
TOP2A 		P11388 DNA topoisomerase II alpha 168 0.497 0.731 0.99 0.350 None 1.000 5 0 1998 2020
Entrez Id: 3240
Gene Symbol: HP
HP 		P00738 haptoglobin Enzyme 411 0.412 0.885 1.7E-05 0.340 None 1.000 4 0 1984 2019
Entrez Id: 3981
Gene Symbol: LIG4
LIG4 		P49917 DNA ligase 4 153 0.478 0.846 4.2E-06 0.340 None 1.000 4 0 1999 2014
Entrez Id: 5347
Gene Symbol: PLK1
PLK1 		P53350 polo like kinase 1 Kinase 249 0.467 0.808 0.98 0.340 None 1.000 4 0 2009 2019