Source: BEFREE ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 4312
Gene Symbol: MMP1
MMP1 		P03956 matrix metallopeptidase 1 Enzyme 507 0.385 0.885 7.7E-18 0.900 limited 0.875 14 3 2002 2019
Entrez Id: 6441
Gene Symbol: SFTPD
SFTPD 		P35247 surfactant protein D Surfactant 179 0.500 0.846 7.5E-05 0.700 None 0.917 20 7 2001 2019
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1 		P09601 heme oxygenase 1 510 0.381 0.923 9.7E-03 0.700 None 0.900 19 1 2005 2020
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1 		P01137 transforming growth factor beta 1 Signaling 1334 0.287 0.962 3.7E-02 0.600 None 0.911 42 5 1994 2020
Entrez Id: 4318
Gene Symbol: MMP9
MMP9 		P14780 matrix metallopeptidase 9 Enzyme 1160 0.305 0.923 1.9E-17 0.600 None 0.979 41 4 2002 2019
Entrez Id: 3066
Gene Symbol: HDAC2
HDAC2 		Q92769 histone deacetylase 2 Epigenetic regulator 228 0.476 0.846 1.00 0.600 None 1.000 19 0 2004 2019
Entrez Id: 5265
Gene Symbol: SERPINA1
SERPINA1 		P01009 serpin family A member 1 Enzyme modulator 411 0.410 0.923 6.8E-08 0.500 None 0.990 91 9 1977 2020
Entrez Id: 10144
Gene Symbol: FAM13A
FAM13A 		O94988 family with sequence similarity 13 member A 24 0.653 0.462 1.9E-18 0.500 None 1.000 25 6 2010 2019
Entrez Id: 1832
Gene Symbol: DSP
DSP 		P15924 desmoplakin Cellular structure 112 0.514 0.808 1.00 0.420 None 1.000 2 1 2017 2019
Entrez Id: 7124
Gene Symbol: TNF
TNF 		P01375 tumor necrosis factor Signaling 2475 0.231 0.962 0.80 0.400 None 0.952 78 3 2000 2020
Entrez Id: 3569
Gene Symbol: IL6
IL6 		P05231 interleukin 6 2132 0.248 0.962 0.32 0.400 None 0.967 57 1 2006 2020
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8 		P10145 C-X-C motif chemokine ligand 8 Signaling 1173 0.310 0.962 2.7E-04 0.400 None 0.965 53 0 2000 2020
Entrez Id: 2006
Gene Symbol: ELN
ELN 		P15502 elastin 302 0.415 0.885 2.1E-14 0.400 None 1.000 27 1 2005 2019
Entrez Id: 2052
Gene Symbol: EPHX1
EPHX1 		P07099 epoxide hydrolase 1 137 0.500 0.846 3.2E-09 0.400 None 0.923 26 3 1997 2017
Entrez Id: 4846
Gene Symbol: NOS3
NOS3 		P29474 nitric oxide synthase 3 559 0.378 0.885 6.7E-07 0.380 None 1.000 6 1 2003 2015
Entrez Id: 6649
Gene Symbol: SOD3
SOD3 		P08294 superoxide dismutase 3 Enzyme 115 0.531 0.808 7.2E-04 0.370 None 1.000 7 3 2006 2019
Entrez Id: 1543
Gene Symbol: CYP1A1
CYP1A1 		P04798 cytochrome P450 family 1 subfamily A member 1 Enzyme 323 0.436 0.846 1.1E-17 0.370 None 1.000 6 0 2008 2019
Entrez Id: 2309
Gene Symbol: FOXO3
FOXO3 		O43524 forkhead box O3 355 0.431 0.808 0.99 0.350 None 1.000 5 0 2011 2018
Entrez Id: 4843
Gene Symbol: NOS2
NOS2 		P35228 nitric oxide synthase 2 572 0.364 0.923 4.0E-15 0.350 None 0.833 3 0 2003 2015
Entrez Id: 2919
Gene Symbol: CXCL1
CXCL1 		P09341 C-X-C motif chemokine ligand 1 Signaling 269 0.449 0.923 0.12 0.340 None 1.000 4 0 2013 2019
Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A 		P28223 5-hydroxytryptamine receptor 2A G-protein coupled receptor 236 0.473 0.846 0.51 0.330 None 1.000 3 1 2012 2020
Entrez Id: 59341
Gene Symbol: TRPV4
TRPV4 		Q9HBA0 transient receptor potential cation channel subfamily V member 4 Ion channel 207 0.457 0.808 2.2E-16 0.330 None 1.000 3 0 2009 2011
Entrez Id: 1544
Gene Symbol: CYP1A2
CYP1A2 		P05177 cytochrome P450 family 1 subfamily A member 2 Enzyme 168 0.494 0.923 2.5E-10 0.330 None 1.000 2 0 2008 2010
Entrez Id: 10411
Gene Symbol: RAPGEF3
RAPGEF3 		O95398 Rap guanine nucleotide exchange factor 3 Enzyme modulator 83 0.593 0.692 7.1E-23 0.320 None 1.000 2 0 2012 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 2245 0.236 0.962 0.53 0.320 None 1.000 2 0 2006 2016