Source: BEFREE ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		P12830 cadherin 1 396 0.401 0.808 0.15 0.800 None 0.933 129 5 1996 2020
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		P04626 erb-b2 receptor tyrosine kinase 2 Kinase 942 0.328 0.923 6.0E-03 0.700 None 0.963 377 4 1988 2020
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1277 0.292 0.923 1.00 0.700 None 0.992 120 0 2005 2020
Entrez Id: 4233
Gene Symbol: MET
MET 		P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 501 0.380 0.846 0.97 0.700 None 0.983 57 1 1992 2019
Entrez Id: 2263
Gene Symbol: FGFR2
FGFR2 		P21802 fibroblast growth factor receptor 2 Kinase 345 0.380 0.808 1.00 0.700 None 0.957 44 0 1996 2019
Entrez Id: 324
Gene Symbol: APC
APC 		P25054 APC regulator of WNT signaling pathway 517 0.373 0.962 1.00 0.700 None 0.950 20 0 1992 2019
Entrez Id: 1316
Gene Symbol: KLF6
KLF6 		Q99612 Kruppel like factor 6 Nucleic acid binding 192 0.501 0.846 0.98 0.660 None 1.000 6 0 2005 2019
Entrez Id: 3659
Gene Symbol: IRF1
IRF1 		P10914 interferon regulatory factor 1 Transcription factor 230 0.468 0.769 0.99 0.660 None 1.000 6 1 1998 2019
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		Q9UIF7 mutY DNA glycosylase Enzyme 130 0.521 0.769 1.3E-18 0.640 None 1.000 4 2 2004 2011
Entrez Id: 843
Gene Symbol: CASP10
CASP10 		Q92851 caspase 10 Enzyme 84 0.528 0.692 4.6E-12 0.610 None 1.000 1 0 2002 2002
Entrez Id: 472
Gene Symbol: ATM
ATM 		Q13315 ATM serine/threonine kinase Kinase 563 0.374 0.885 5.6E-47 0.600 None 1.000 20 0 1998 2019
Entrez Id: 3553
Gene Symbol: IL1B
IL1B 		P01584 interleukin 1 beta 1604 0.276 0.962 0.13 0.500 None 0.907 52 4 2000 2018
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN 		P18510 interleukin 1 receptor antagonist 600 0.373 0.923 3.1E-02 0.500 None 0.833 36 2 2003 2018
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		P01116 KRAS proto-oncogene, GTPase Enzyme modulator 805 0.320 0.923 7.9E-04 0.500 None 1.000 29 2 1987 2019
Entrez Id: 5562
Gene Symbol: PRKAA1
PRKAA1 		Q13131 protein kinase AMP-activated catalytic subunit alpha 1 Kinase 313 0.453 0.846 0.14 0.500 None 0.944 17 6 2011 2019
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2 		O96017 checkpoint kinase 2 Kinase 220 0.460 0.808 1.2E-24 0.460 None 0.857 6 0 2000 2018
Entrez Id: 26137
Gene Symbol: ZBTB20
ZBTB20 		Q9HC78 zinc finger and BTB domain containing 20 41 0.566 0.731 0.97 0.430 None 1.000 3 1 2011 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 2245 0.236 0.962 0.53 0.400 None 0.975 199 4 1991 2020
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1043 0.314 0.962 1.00 0.400 None 0.979 94 8 1998 2020
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		P00533 epidermal growth factor receptor Kinase 1308 0.295 0.885 0.37 0.400 None 0.989 91 6 1986 2019
Entrez Id: 6774
Gene Symbol: STAT3
STAT3 		P40763 signal transducer and activator of transcription 3 Nucleic acid binding 999 0.320 0.923 1.00 0.400 None 1.000 68 2 2005 2019
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8 		P10145 C-X-C motif chemokine ligand 8 Signaling 1173 0.310 0.962 2.7E-04 0.400 None 0.950 59 2 1992 2019
Entrez Id: 864
Gene Symbol: RUNX3
RUNX3 		Q13761 RUNX family transcription factor 3 Transcription factor 256 0.459 0.731 0.84 0.400 None 0.950 59 1 2002 2018
Entrez Id: 7124
Gene Symbol: TNF
TNF 		P01375 tumor necrosis factor Signaling 2475 0.231 0.962 0.80 0.400 None 0.912 55 5 1992 2019
Entrez Id: 960
Gene Symbol: CD44
CD44 		P16070 CD44 molecule (Indian blood group) 664 0.363 0.962 2.4E-07 0.400 None 0.982 55 2 1993 2019