Entrez Id: |
5727 |
Gene Symbol: |
PTCH1 |
PTCH1
|
Q13635
|
patched 1
|
|
604
|
0.398 |
0.885 |
1.00 |
0.900 |
None
|
0.985 |
66
|
4
|
1997 |
2020 |
Entrez Id: |
1499 |
Gene Symbol: |
CTNNB1 |
CTNNB1
|
P35222
|
catenin beta 1
|
|
1368
|
0.303 |
0.885 |
1.00 |
0.800 |
None
|
0.979 |
47
|
9
|
1998 |
2020 |
Entrez Id: |
51684 |
Gene Symbol: |
SUFU |
SUFU
|
Q9UMX1
|
SUFU negative regulator of hedgehog signaling
|
|
272
|
0.493 |
0.769 |
1.00 |
0.800 |
definitive
|
0.950 |
20
|
14
|
1996 |
2019 |
Entrez Id: |
324 |
Gene Symbol: |
APC |
APC
|
P25054
|
APC regulator of WNT signaling pathway
|
|
703
|
0.373 |
0.962 |
1.00 |
0.700 |
None
|
1.000 |
18
|
5
|
1995 |
2020 |
Entrez Id: |
6608 |
Gene Symbol: |
SMO |
SMO
|
Q99835
|
smoothened, frizzled class receptor
|
G-protein coupled receptor
|
215
|
0.489 |
0.731 |
4.3E-07 |
0.690 |
None
|
1.000 |
11
|
2
|
2000 |
2020 |
Entrez Id: |
675 |
Gene Symbol: |
BRCA2 |
BRCA2
|
P51587
|
BRCA2 DNA repair associated
|
Nucleic acid binding
|
656
|
0.379 |
0.846 |
2.4E-25 |
0.630 |
strong
|
1.000 |
6
|
24
|
2003 |
2018 |
Entrez Id: |
4683 |
Gene Symbol: |
NBN |
NBN
|
O60934
|
nibrin
|
Nucleic acid binding
|
291
|
0.467 |
0.808 |
2.2E-16 |
0.620 |
strong
|
1.000 |
3
|
2
|
2008 |
2017 |
Entrez Id: |
8643 |
Gene Symbol: |
PTCH2 |
PTCH2
|
Q9Y6C5
|
patched 2
|
|
114
|
0.563 |
0.692 |
3.4E-16 |
0.610 |
moderate
|
1.000 |
1
|
1
|
1999 |
1999 |
Entrez Id: |
472 |
Gene Symbol: |
ATM |
ATM
|
Q13315
|
ATM serine/threonine kinase
|
Kinase
|
684
|
0.374 |
0.885 |
5.6E-47 |
0.510 |
strong
|
0.500 |
2
|
1
|
2003 |
2017 |
Entrez Id: |
4613 |
Gene Symbol: |
MYCN |
MYCN
|
P04198
|
MYCN proto-oncogene, bHLH transcription factor
|
Transcription factor
|
314
|
0.454 |
0.808 |
0.89 |
0.500 |
None
|
0.971 |
34
|
2
|
1989 |
2019 |
Entrez Id: |
5395 |
Gene Symbol: |
PMS2 |
PMS2
|
P54278
|
PMS1 homolog 2, mismatch repair system component
|
Nucleic acid binding
|
244
|
0.484 |
0.808 |
4.5E-27 |
0.420 |
None
|
1.000 |
2
|
2
|
2009 |
2013 |
Entrez Id: |
4609 |
Gene Symbol: |
MYC |
MYC
|
P01106
|
MYC proto-oncogene, bHLH transcription factor
|
Transcription factor
|
821
|
0.344 |
0.923 |
1.00 |
0.400 |
None
|
0.974 |
77
|
0
|
1990 |
2019 |
Entrez Id: |
5015 |
Gene Symbol: |
OTX2 |
OTX2
|
P32243
|
orthodenticle homeobox 2
|
Transcription factor
|
200
|
0.514 |
0.808 |
0.92 |
0.400 |
None
|
1.000 |
26
|
0
|
1999 |
2019 |
Entrez Id: |
5294 |
Gene Symbol: |
PIK3CG |
PIK3CG
|
P48736
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
|
Kinase
|
1101
|
0.320 |
0.885 |
1.4E-06 |
0.400 |
None
|
1.000 |
15
|
0
|
2005 |
2019 |
Entrez Id: |
6774 |
Gene Symbol: |
STAT3 |
STAT3
|
P40763
|
signal transducer and activator of transcription 3
|
Nucleic acid binding
|
1193
|
0.320 |
0.923 |
1.00 |
0.400 |
None
|
1.000 |
14
|
0
|
2008 |
2019 |
Entrez Id: |
474 |
Gene Symbol: |
ATOH1 |
ATOH1
|
Q92858
|
atonal bHLH transcription factor 1
|
Enzyme
|
53
|
0.633 |
0.500 |
1.8E-02 |
0.400 |
None
|
1.000 |
10
|
0
|
2007 |
2019 |
Entrez Id: |
79728 |
Gene Symbol: |
PALB2 |
PALB2
|
Q86YC2
|
partner and localizer of BRCA2
|
|
260
|
0.485 |
0.769 |
3.0E-19 |
0.400 |
None
|
|
0
|
0
|
|
|
Entrez Id: |
3090 |
Gene Symbol: |
HIC1 |
HIC1
|
Q14526
|
HIC ZBTB transcriptional repressor 1
|
Transcription factor
|
163
|
0.522 |
0.615 |
0.13 |
0.390 |
None
|
1.000 |
9
|
0
|
2002 |
2008 |
Entrez Id: |
1021 |
Gene Symbol: |
CDK6 |
CDK6
|
Q00534
|
cyclin dependent kinase 6
|
Kinase
|
266
|
0.471 |
0.731 |
0.98 |
0.380 |
None
|
1.000 |
10
|
0
|
2005 |
2018 |
Entrez Id: |
2064 |
Gene Symbol: |
ERBB2 |
ERBB2
|
P04626
|
erb-b2 receptor tyrosine kinase 2
|
Kinase
|
995
|
0.328 |
0.923 |
6.0E-03 |
0.370 |
None
|
1.000 |
8
|
0
|
2001 |
2018 |
Entrez Id: |
11186 |
Gene Symbol: |
RASSF1 |
RASSF1
|
Q9NS23
|
Ras association domain family member 1
|
Enzyme modulator
|
400
|
0.420 |
0.808 |
4.9E-06 |
0.370 |
None
|
1.000 |
7
|
0
|
2002 |
2011 |
Entrez Id: |
5156 |
Gene Symbol: |
PDGFRA |
PDGFRA
|
P16234
|
platelet derived growth factor receptor alpha
|
Kinase
|
452
|
0.415 |
0.808 |
1.00 |
0.360 |
None
|
1.000 |
7
|
0
|
2001 |
2015 |
Entrez Id: |
2100 |
Gene Symbol: |
ESR2 |
ESR2
|
Q92731
|
estrogen receptor 2
|
Nuclear receptor
|
528
|
0.400 |
0.923 |
4.5E-08 |
0.350 |
None
|
1.000 |
6
|
0
|
2009 |
2017 |
Entrez Id: |
23476 |
Gene Symbol: |
BRD4 |
BRD4
|
O60885
|
bromodomain containing 4
|
Epigenetic regulator
|
335
|
0.446 |
0.885 |
1.00 |
0.340 |
None
|
1.000 |
5
|
0
|
2013 |
2019 |
Entrez Id: |
1786 |
Gene Symbol: |
DNMT1 |
DNMT1
|
P26358
|
DNA methyltransferase 1
|
Epigenetic regulator
|
496
|
0.406 |
0.885 |
1.00 |
0.340 |
None
|
1.000 |
5
|
0
|
2009 |
2018 |