Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 79671
Gene Symbol: NLRX1
NLRX1
Q86UT6 NLR family member X1 Enzyme 51 0.641 0.654 7.7E-31 0.010 None 1.000 1 0 2018 2018
Entrez Id: 91662
Gene Symbol: NLRP12
NLRP12
P59046 NLR family pyrin domain containing 12 95 0.569 0.846 3.6E-28 0.010 None 1.000 1 0 2018 2018
Entrez Id: 7450
Gene Symbol: VWF
VWF
P04275 von Willebrand factor Enzyme modulator 498 0.408 0.885 3.2E-25 0.020 None 1.000 2 0 2019 2020
Entrez Id: 6833
Gene Symbol: ABCC8
ABCC8
Q09428 ATP binding cassette subfamily C member 8 Transporter 317 0.474 0.846 8.0E-24 0.010 None 1.000 1 0 2006 2006
Entrez Id: 4855
Gene Symbol: NOTCH4
NOTCH4
Q99466 notch receptor 4 150 0.534 0.731 2.1E-23 0.010 None 1.000 1 0 2017 2017
Entrez Id: 4645
Gene Symbol: MYO5B
MYO5B
Q9ULV0 myosin VB Cellular structure 60 0.641 0.731 3.4E-23 0.010 None 1.000 1 0 2014 2014
Entrez Id: 7096
Gene Symbol: TLR1
TLR1
Q15399 toll like receptor 1 198 0.496 0.808 5.9E-23 0.010 None 1.000 1 3 2017 2017
Entrez Id: 3710
Gene Symbol: ITPR3
ITPR3
Q14573 inositol 1,4,5-trisphosphate receptor type 3 Ion channel 112 0.555 0.808 2.6E-22 0.010 None 1.000 1 1 2010 2010
Entrez Id: 7941
Gene Symbol: PLA2G7
PLA2G7
Q13093 phospholipase A2 group VII Enzyme 136 0.537 0.769 5.3E-22 0.010 None 1.000 1 1 2005 2005
Entrez Id: 375033
Gene Symbol: PEAR1
PEAR1
Q5VY43 platelet endothelial aggregation receptor 1 27 0.722 0.346 3.5E-20 0.010 None < 0.001 1 1 2019 2019
Entrez Id: 4091
Gene Symbol: SMAD6
SMAD6
O43541 SMAD family member 6 Transcription factor 93 0.579 0.731 3.6E-20 0.010 None 1.000 1 0 2018 2018
Entrez Id: 6556
Gene Symbol: SLC11A1
SLC11A1
P49279 solute carrier family 11 member 1 Transporter 141 0.525 0.846 1.5E-19 0.020 None 1.000 2 1 2003 2018
Entrez Id: 2875
Gene Symbol: GPT
GPT
P24298 glutamic--pyruvic transaminase Enzyme 511 0.403 0.923 3.6E-19 0.030 None 0.667 3 0 2018 2018
Entrez Id: 22861
Gene Symbol: NLRP1
NLRP1
Q9C000 NLR family pyrin domain containing 1 200 0.502 0.769 5.0E-19 0.010 None 1.000 1 0 2012 2012
Entrez Id: 10392
Gene Symbol: NOD1
NOD1
Q9Y239 nucleotide binding oligomerization domain containing 1 Enzyme 136 0.541 0.769 2.5E-18 0.020 None 1.000 2 0 2012 2017
Entrez Id: 4322
Gene Symbol: MMP13
MMP13
P45452 matrix metallopeptidase 13 Enzyme 328 0.452 0.923 7.9E-18 0.010 None 1.000 1 0 2008 2008
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
P14780 matrix metallopeptidase 9 Enzyme 1337 0.305 0.923 1.9E-17 0.080 None 1.000 8 0 2001 2019
Entrez Id: 2219
Gene Symbol: FCN1
FCN1
O00602 ficolin 1 Signaling 43 0.647 0.577 4.0E-17 0.020 None 1.000 2 0 2017 2019
Entrez Id: 6295
Gene Symbol: SAG
SAG
P10523 S-antigen visual arrestin Enzyme modulator 97 0.570 0.731 1.5E-16 0.010 None 1.000 1 0 2009 2009
Entrez Id: 338
Gene Symbol: APOB
APOB
P04114 apolipoprotein B 339 0.453 0.808 1.9E-16 0.010 None 1.000 1 0 2019 2019
Entrez Id: 177
Gene Symbol: AGER
AGER
Q15109 advanced glycosylation end-product specific receptor Receptor 450 0.420 0.885 6.4E-16 0.010 None 1.000 1 0 2019 2019
Entrez Id: 4843
Gene Symbol: NOS2
NOS2
P35228 nitric oxide synthase 2 783 0.364 0.923 4.0E-15 0.010 None 1.000 1 0 2004 2004
Entrez Id: 11093
Gene Symbol: ADAMTS13
ADAMTS13
Q76LX8 ADAM metallopeptidase with thrombospondin type 1 motif 13 Enzyme 229 0.496 0.769 5.1E-15 0.010 None 1.000 1 0 2019 2019
Entrez Id: 219285
Gene Symbol: SAMD9L
SAMD9L
Q8IVG5 sterile alpha motif domain containing 9 like 49 0.700 0.500 5.6E-15 0.010 None 1.000 1 1 2020 2020
Entrez Id: 4314
Gene Symbol: MMP3
MMP3
P08254 matrix metallopeptidase 3 Enzyme 473 0.408 0.885 5.7E-15 0.020 None 1.000 2 0 2005 2008