Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 207
Gene Symbol: AKT1
AKT1
P31749 AKT serine/threonine kinase 1 Kinase 1250 0.311 0.962 0.98 0.100 None 1.000 218 2 2002 2020
Entrez Id: 60
Gene Symbol: ACTB
ACTB
P60709 actin beta Cellular structure 1110 0.325 0.923 0.99 0.100 None 1.000 125 0 1996 2019
Entrez Id: 100124700
Gene Symbol: HOTAIR
HOTAIR
HOX transcript antisense RNA 234 0.475 0.769 0.100 None 1.000 90 1 2010 2019
Entrez Id: 6615
Gene Symbol: SNAI1
SNAI1
O95863 snail family transcriptional repressor 1 243 0.474 0.808 0.22 0.400 None 1.000 79 1 2007 2020
Entrez Id: 10397
Gene Symbol: NDRG1
NDRG1
Q92597 N-myc downstream regulated 1 Enzyme 225 0.488 0.731 1.1E-02 0.400 None 1.000 78 0 2003 2020
Entrez Id: 25855
Gene Symbol: BRMS1
BRMS1
Q9HCU9 BRMS1 transcriptional repressor and anoikis regulator 72 0.597 0.615 1.6E-07 0.400 None 1.000 76 0 2000 2019
Entrez Id: 406937
Gene Symbol: MIR145
MIR145
microRNA 145 366 0.431 0.846 0.100 None 1.000 70 1 2010 2020
Entrez Id: 5340
Gene Symbol: PLG
PLG
P00747 plasminogen Enzyme 586 0.389 0.923 1.0E-02 0.100 None 1.000 69 0 1983 2019
Entrez Id: 5595
Gene Symbol: MAPK3
MAPK3
P27361 mitogen-activated protein kinase 3 Kinase 647 0.379 0.885 3.7E-02 0.400 None 1.000 69 0 1998 2020
Entrez Id: 4089
Gene Symbol: SMAD4
SMAD4
Q13485 SMAD family member 4 Transcription factor 575 0.401 0.808 1.00 0.100 None 1.000 65 0 1999 2020
Entrez Id: 4851
Gene Symbol: NOTCH1
NOTCH1
P46531 notch receptor 1 693 0.369 0.885 1.00 0.100 None 1.000 64 0 2001 2019
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
P05019 insulin like growth factor 1 1206 0.318 0.885 0.27 0.400 None 1.000 62 1 1997 2019
Entrez Id: 3791
Gene Symbol: KDR
KDR
P35968 kinase insert domain receptor Kinase 623 0.378 0.885 1.00 0.100 None 1.000 59 1 1995 2020
Entrez Id: 8842
Gene Symbol: PROM1
PROM1
O43490 prominin 1 Transporter 477 0.410 0.846 1.9E-22 0.100 None 1.000 56 1 2006 2020
Entrez Id: 29072
Gene Symbol: SETD2
SETD2
Q9BYW2 SET domain containing 2, histone lysine methyltransferase Epigenetic regulator 447 0.424 0.846 1.00 0.100 None 1.000 55 0 2002 2020
Entrez Id: 302
Gene Symbol: ANXA2
ANXA2
P07355 annexin A2 294 0.453 0.808 9.8E-05 0.100 None 1.000 54 0 1993 2019
Entrez Id: 9839
Gene Symbol: ZEB2
ZEB2
O60315 zinc finger E-box binding homeobox 2 Transcription factor 292 0.471 0.808 1.00 0.100 None 1.000 54 0 2006 2020
Entrez Id: 7076
Gene Symbol: TIMP1
TIMP1
P01033 TIMP metallopeptidase inhibitor 1 Enzyme modulator 603 0.380 0.885 0.50 0.100 None 1.000 53 0 1993 2020
Entrez Id: 6657
Gene Symbol: SOX2
SOX2
P48431 SRY-box transcription factor 2 Transcription factor 503 0.405 0.808 0.71 0.100 None 1.000 52 0 2006 2020
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
P05362 intercellular adhesion molecule 1 737 0.364 0.962 3.5E-02 0.100 None 1.000 51 0 1989 2019
Entrez Id: 406985
Gene Symbol: MIR200C
MIR200C
microRNA 200c 202 0.486 0.846 0.100 None 1.000 49 0 2010 2020
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
Q96EB6 sirtuin 1 Epigenetic regulator 675 0.378 0.885 8.7E-02 0.400 None 1.000 47 0 2011 2019
Entrez Id: 5744
Gene Symbol: PTHLH
PTHLH
P12272 parathyroid hormone like hormone 321 0.453 0.846 0.81 0.100 None 1.000 47 0 1992 2020
Entrez Id: 5747
Gene Symbol: PTK2
PTK2
Q05397 protein tyrosine kinase 2 Kinase 205 0.497 0.808 1.00 0.300 None 1.000 45 1 1996 2019
Entrez Id: 860
Gene Symbol: RUNX2
RUNX2
Q13950 RUNX family transcription factor 2 Transcription factor 405 0.437 0.846 0.95 0.100 None 1.000 45 0 2003 2019