Source: CLINVAR ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		P42771 Q8N726 cyclin dependent kinase inhibitor 2A 22 0.300 0.885 0.39 0.500 None 0.944 1 7 1984 2020
Entrez Id: 1436
Gene Symbol: CSF1R
CSF1R 		P07333 colony stimulating factor 1 receptor Kinase 16 0.448 0.808 0.13 0.500 None 0.960 1 4 1987 2020
Entrez Id: 4609
Gene Symbol: MYC
MYC 		P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 6 0.344 0.923 1.00 0.500 None 0.967 1 6 1983 2020
Entrez Id: 472
Gene Symbol: ATM
ATM 		Q13315 ATM serine/threonine kinase Kinase 44 0.374 0.885 5.6E-47 0.500 None 0.946 0 2 1995 2020
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 84 0.236 0.962 0.53 0.200 None 0.947 5 6 1987 2020
Entrez Id: 5295
Gene Symbol: PIK3R1
PIK3R1 		P27986 phosphoinositide-3-kinase regulatory subunit 1 Kinase 10 0.477 0.885 1.00 0.200 None 0.960 3 9 1998 2019
Entrez Id: 2778
Gene Symbol: GNAS
GNAS 		O95467 P63092 P84996 Q5JWF2 GNAS complex locus Enzyme modulator 60 0.420 0.885 0.68 0.200 None 0.941 2 3 1998 2020
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 125 0.319 0.846 1.00 0.200 None 0.946 2 10 2002 2020
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		P04626 erb-b2 receptor tyrosine kinase 2 Kinase 23 0.328 0.923 6.0E-03 0.200 None 0.945 2 2 1987 2020
Entrez Id: 5604
Gene Symbol: MAP2K1
MAP2K1 		Q02750 mitogen-activated protein kinase kinase 1 Kinase 26 0.439 0.846 0.90 0.200 None 0.927 2 7 1996 2019
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		P60484 phosphatase and tensin homolog Enzyme 107 0.305 0.923 0.26 0.200 None 0.976 1 1 1997 2020
Entrez Id: 5925
Gene Symbol: RB1
RB1 		P06400 RB transcriptional corepressor 1 Nucleic acid binding 11 0.444 0.885 1.00 0.200 None 0.972 1 3 1988 2019
Entrez Id: 5979
Gene Symbol: RET
RET 		P07949 ret proto-oncogene Kinase 36 0.392 0.885 1.00 0.200 None 0.940 1 2 1989 2020
Entrez Id: 6714
Gene Symbol: SRC
SRC 		P12931 SRC proto-oncogene, non-receptor tyrosine kinase Kinase 5 0.467 0.885 1.00 0.200 None 0.983 1 1 1987 2019
Entrez Id: 6794
Gene Symbol: STK11
STK11 		Q15831 serine/threonine kinase 11 Kinase 22 0.435 0.808 0.99 0.200 None 0.976 1 7 1998 2020
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 85 0.292 0.923 1.00 0.200 None 0.977 1 1 1998 2020
Entrez Id: 7428
Gene Symbol: VHL
VHL 		P40337 von Hippel-Lindau tumor suppressor Enzyme 14 0.443 0.846 8.0E-02 0.200 None 0.953 1 2 1989 2020
Entrez Id: 4893
Gene Symbol: NRAS
NRAS 		P01111 NRAS proto-oncogene, GTPase Enzyme modulator 37 0.390 0.808 0.49 0.200 None 0.926 1 1 1986 2020
Entrez Id: 3265
Gene Symbol: HRAS
HRAS 		P01112 HRas proto-oncogene, GTPase Enzyme modulator 71 0.378 0.885 8.0E-02 0.200 None 0.975 1 4 1983 2019
Entrez Id: 324
Gene Symbol: APC
APC 		P25054 APC regulator of WNT signaling pathway 33 0.373 0.962 1.00 0.200 None 0.967 1 4 1991 2020
Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1 		P11362 fibroblast growth factor receptor 1 Kinase 27 0.362 0.885 1.00 0.200 None 0.964 1 2 1994 2020
Entrez Id: 2065
Gene Symbol: ERBB3
ERBB3 		P21860 erb-b2 receptor tyrosine kinase 3 Kinase 12 0.448 0.808 1.7E-15 0.200 None 0.962 1 2 1993 2019
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		P35222 catenin beta 1 70 0.303 0.885 1.00 0.200 None 0.955 1 2 1994 2020
Entrez Id: 7249
Gene Symbol: TSC2
TSC2 		P49815 TSC complex subunit 2 Enzyme modulator 13 0.439 0.808 1.00 0.200 None 0.971 0 2 1990 2020
Entrez Id: 100270680
Gene Symbol: CASC11
CASC11 		cancer susceptibility 11 6 0.641 0.577 0.140 None 1.000 1 5 2014 2019