Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 6392
Gene Symbol: SDHD
SDHD 		O14521 succinate dehydrogenase complex subunit D Transporter 348 0.472 0.885 0.34 0.100 None 1.000 72 31 1998 2016
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.170 None 1.000 367 203 1989 2018
Entrez Id: 4089
Gene Symbol: SMAD4
SMAD4 		Q13485 SMAD family member 4 Transcription factor 575 0.401 0.808 1.00 0.100 None 1.000 35 35 1998 2017
Entrez Id: 4149
Gene Symbol: MAX
MAX 		P61244 MYC associated factor X Transcription factor 141 0.553 0.769 0.83 0.100 None 1.000 6 9 2003 2017
Entrez Id: 861
Gene Symbol: RUNX1
RUNX1 		Q01196 RUNX family transcription factor 1 Transcription factor 412 0.425 0.808 0.65 0.010 None 1.000 1 0 2016 2016
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		P51587 BRCA2 DNA repair associated Nucleic acid binding 656 0.379 0.846 2.4E-25 0.130 None 1.000 704 1021 1996 2019
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		P43246 mutS homolog 2 Nucleic acid binding 490 0.406 0.808 0.90 0.130 None 1.000 323 309 1990 2018
Entrez Id: 4292
Gene Symbol: MLH1
MLH1 		P40692 mutL homolog 1 Nucleic acid binding 526 0.399 0.808 3.4E-05 0.150 None 1.000 303 189 1978 2018
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		P52701 mutS homolog 6 Nucleic acid binding 296 0.462 0.731 3.7E-05 0.110 None 1.000 191 331 1994 2018
Entrez Id: 5395
Gene Symbol: PMS2
PMS2 		P54278 PMS1 homolog 2, mismatch repair system component Nucleic acid binding 244 0.484 0.808 4.5E-27 0.110 None 1.000 113 124 1995 2018
Entrez Id: 5925
Gene Symbol: RB1
RB1 		P06400 RB transcriptional corepressor 1 Nucleic acid binding 339 0.444 0.885 1.00 0.100 None 1.000 71 103 1989 2018
Entrez Id: 4683
Gene Symbol: NBN
NBN 		O60934 nibrin Nucleic acid binding 291 0.467 0.808 2.2E-16 0.100 None 1.000 36 92 1998 2017
Entrez Id: 114034
Gene Symbol: TOE1
TOE1 		Q96GM8 target of EGR1, exonuclease Nucleic acid binding 51 0.682 0.462 6.0E-16 0.100 None 1.000 2 2 2006 2007
Entrez Id: 4437
Gene Symbol: MSH3
MSH3 		P20585 mutS homolog 3 Nucleic acid binding 245 0.474 0.769 7.4E-31 0.010 None 1.000 1 0 2016 2016
Entrez Id: 6598
Gene Symbol: SMARCB1
SMARCB1 		Q12824 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 Nucleic acid binding 448 0.434 0.846 1.00 0.100 None 1.000 1 1 2010 2010
Entrez Id: 51023
Gene Symbol: MRPS18C
MRPS18C 		Q9Y3D5 mitochondrial ribosomal protein S18C Nucleic acid binding 4 0.890 0.154 8.8E-05 0.100 None 0 1
Entrez Id: 472
Gene Symbol: ATM
ATM 		Q13315 ATM serine/threonine kinase Kinase 684 0.374 0.885 5.6E-47 0.100 None 1.000 233 561 1989 2018
Entrez Id: 5979
Gene Symbol: RET
RET 		P07949 ret proto-oncogene Kinase 607 0.392 0.885 1.00 0.200 None 1.000 113 13 1992 2018
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2 		O96017 checkpoint kinase 2 Kinase 297 0.460 0.808 1.2E-24 0.100 None 1.000 106 133 1999 2019
Entrez Id: 6794
Gene Symbol: STK11
STK11 		Q15831 serine/threonine kinase 11 Kinase 372 0.435 0.808 0.99 0.120 None 1.000 41 64 1992 2018
Entrez Id: 657
Gene Symbol: BMPR1A
BMPR1A 		P36894 bone morphogenetic protein receptor type 1A Kinase 203 0.522 0.731 0.90 0.110 None 1.000 19 60 1997 2019
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1511 0.292 0.923 1.00 0.010 None 1.000 1 0 2011 2011
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB 		P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1083 0.322 0.885 1.00 0.010 None 1.000 1 0 2011 2011
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1119 0.319 0.885 1.00 0.010 None 1.000 1 0 2011 2011
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG 		P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1101 0.320 0.885 1.4E-06 0.010 None 1.000 1 0 2011 2011