Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1
P28482 mitogen-activated protein kinase 1 Kinase 1059 0.330 0.923 1.00 0.100 None 1.000 10 0 2007 2017
Entrez Id: 5500
Gene Symbol: PPP1CB
PPP1CB
P62140 protein phosphatase 1 catalytic subunit beta Enzyme 105 0.601 0.577 1.00 0.350 1.000 5 0 2016 2019
Entrez Id: 52
Gene Symbol: ACP1
ACP1
P24666 acid phosphatase 1 107 0.566 0.731 1.8E-08 0.050 None 1.000 5 0 2002 2007
Entrez Id: 5250
Gene Symbol: SLC25A3
SLC25A3
Q00325 solute carrier family 25 member 3 Transporter 112 0.566 0.692 7.5E-02 0.040 None 1.000 4 0 2005 2017
Entrez Id: 5967
Gene Symbol: REG1A
REG1A
P05451 regenerating family member 1 alpha 264 0.467 0.846 1.3E-05 0.040 None 1.000 4 0 2005 2017
Entrez Id: 10076
Gene Symbol: PTPRU
PTPRU
Q92729 protein tyrosine phosphatase receptor type U Enzyme 88 0.581 0.654 0.39 0.040 None 1.000 4 0 2005 2017
Entrez Id: 6655
Gene Symbol: SOS2
SOS2
Q07890 SOS Ras/Rho guanine nucleotide exchange factor 2 Enzyme modulator 92 0.608 0.692 1.00 0.620 moderate 1.000 4 0 2000 2015
Entrez Id: 144568
Gene Symbol: A2ML1
A2ML1
A8K2U0 alpha-2-macroglobulin like 1 Enzyme modulator 94 0.590 0.692 1.6E-34 0.600 disputed 1.000 3 0 2015 2016
Entrez Id: 22800
Gene Symbol: RRAS2
RRAS2
P62070 RAS related 2 Enzyme modulator 48 0.656 0.500 0.97 0.620 strong 1.000 3 0 2014 2019
Entrez Id: 5071
Gene Symbol: PRKN
PRKN
O60260 parkin RBR E3 ubiquitin protein ligase Enzyme 409 0.431 0.846 6.9E-07 0.020 None 1.000 2 0 2010 2015
Entrez Id: 158506
Gene Symbol: CBLL2
CBLL2
Q8N7E2 Cbl proto-oncogene like 2 Enzyme 235 0.476 0.808 0.020 None 1.000 2 0 2010 2015
Entrez Id: 5609
Gene Symbol: MAP2K7
MAP2K7
O14733 mitogen-activated protein kinase kinase 7 Kinase 408 0.419 0.808 1.00 0.020 None 1.000 2 0 2010 2011
Entrez Id: 5595
Gene Symbol: MAPK3
MAPK3
P27361 mitogen-activated protein kinase 3 Kinase 647 0.379 0.885 3.7E-02 0.020 None 1.000 2 0 2007 2008
Entrez Id: 79594
Gene Symbol: MUL1
MUL1
Q969V5 mitochondrial E3 ubiquitin protein ligase 1 241 0.473 0.808 1.9E-06 0.020 None 1.000 2 0 2010 2015
Entrez Id: 4597
Gene Symbol: MVD
MVD
P53602 mevalonate diphosphate decarboxylase 101 0.568 0.769 2.7E-17 0.020 None 1.000 2 0 2011 2013
Entrez Id: 998
Gene Symbol: CDC42
CDC42
P60953 cell division cycle 42 Enzyme modulator 327 0.458 0.846 0.79 0.020 None 1.000 2 0 2018 2018
Entrez Id: 1969
Gene Symbol: EPHA2
EPHA2
P29317 EPH receptor A2 Kinase 187 0.501 0.731 1.1E-05 0.310 None 1.000 2 0 2012 2013
Entrez Id: 64132
Gene Symbol: XYLT2
XYLT2
Q9H1B5 xylosyltransferase 2 138 0.566 0.808 0.93 0.020 None 1.000 2 0 2013 2017
Entrez Id: 56731
Gene Symbol: SLC2A4RG
SLC2A4RG
Q9NR83 SLC2A4 regulator Transcription factor 66 0.615 0.692 0.22 0.010 None < 0.001 1 0 2014 2014
Entrez Id: 5770
Gene Symbol: PTPN1
PTPN1
P18031 protein tyrosine phosphatase non-receptor type 1 169 0.523 0.731 0.81 0.010 None 1.000 1 0 2007 2007
Entrez Id: 92170
Gene Symbol: MTG1
MTG1
Q9BT17 mitochondrial ribosome associated GTPase 1 59 0.621 0.769 1.3E-02 0.010 None 1.000 1 0 2019 2019
Entrez Id: 5598
Gene Symbol: MAPK7
MAPK7
Q13164 mitogen-activated protein kinase 7 Kinase 127 0.553 0.654 3.1E-03 0.010 None 1.000 1 0 2019 2019
Entrez Id: 90
Gene Symbol: ACVR1
ACVR1
Q04771 activin A receptor type 1 Kinase 144 0.535 0.731 0.33 0.010 None 1.000 1 0 2016 2016
Entrez Id: 995
Gene Symbol: CDC25C
CDC25C
P30307 cell division cycle 25C Enzyme 95 0.576 0.769 4.1E-13 0.010 None 1.000 1 0 2002 2002
Entrez Id: 4851
Gene Symbol: NOTCH1
NOTCH1
P46531 notch receptor 1 693 0.369 0.885 1.00 0.010 None 1.000 1 0 2010 2010