Source: INFERRED ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 4160
Gene Symbol: MC4R
MC4R 		P32245 melanocortin 4 receptor G-protein coupled receptor 18 0.535 0.692 9.2E-04 1.000 None 0.961 20 19 1997 2020
Entrez Id: 5468
Gene Symbol: PPARG
PPARG 		P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 135 0.358 0.885 2.9E-02 1.000 None 0.960 0 0 1997 2020
Entrez Id: 5443
Gene Symbol: POMC
POMC 		P01189 proopiomelanocortin 27 0.356 0.846 1.2E-04 0.900 strong 0.959 0 0 1996 2020
Entrez Id: 25970
Gene Symbol: SH2B1
SH2B1 		Q9NRF2 SH2B adaptor protein 1 76 0.566 0.731 0.97 0.700 moderate 0.906 1 1 2009 2020
Entrez Id: 3953
Gene Symbol: LEPR
LEPR 		P48357 leptin receptor Signaling 47 0.433 0.808 0.99 0.700 None 0.930 1 2 1966 2019
Entrez Id: 6492
Gene Symbol: SIM1
SIM1 		P81133 SIM bHLH transcription factor 1 Transcription factor 48 0.626 0.654 1.00 0.700 strong 0.955 0 0 1998 2019
Entrez Id: 181
Gene Symbol: AGRP
AGRP 		O00253 agouti related neuropeptide Signaling 5 0.488 0.769 7.0E-04 0.700 None 0.938 0 0 1997 2019
Entrez Id: 5167
Gene Symbol: ENPP1
ENPP1 		P22413 ectonucleotide pyrophosphatase/phosphodiesterase 1 Enzyme 106 0.498 0.808 5.0E-08 0.700 moderate 0.786 0 0 2001 2019
Entrez Id: 5122
Gene Symbol: PCSK1
PCSK1 		P29120 proprotein convertase subtilisin/kexin type 1 Enzyme 37 0.548 0.615 2.7E-09 0.700 None 0.857 0 0 1997 2018
Entrez Id: 3952
Gene Symbol: LEP
LEP 		P41159 leptin 27 0.349 0.846 0.46 0.700 None 0.952 0 0 1973 2020
Entrez Id: 7352
Gene Symbol: UCP3
UCP3 		P55916 uncoupling protein 3 Transporter 4 0.619 0.577 9.6E-10 0.700 None 0.907 0 0 1998 2018
Entrez Id: 8431
Gene Symbol: NR0B2
NR0B2 		Q15466 nuclear receptor subfamily 0 group B member 2 Nuclear receptor 4 0.474 0.808 8.3E-06 0.690 limited 1.000 0 0 2001 2020
Entrez Id: 585
Gene Symbol: BBS4
BBS4 		Q96RK4 Bardet-Biedl syndrome 4 48 0.647 0.615 1.5E-16 0.660 strong 1.000 0 0 2001 2019
Entrez Id: 8195
Gene Symbol: MKKS
MKKS 		Q9NPJ1 McKusick-Kaufman syndrome 79 0.566 0.692 2.1E-09 0.660 strong 0.833 0 0 2000 2013
Entrez Id: 582
Gene Symbol: BBS1
BBS1 		Q8NFJ9 Bardet-Biedl syndrome 1 92 0.593 0.692 3.4E-12 0.620 strong 1.000 0 0 2002 2013
Entrez Id: 79068
Gene Symbol: FTO
FTO 		Q9C0B1 FTO alpha-ketoglutarate dependent dioxygenase 100 0.486 0.885 8.4E-08 0.500 None 0.953 11 58 2007 2020
Entrez Id: 51738
Gene Symbol: GHRL
GHRL 		Q9UBU3 ghrelin and obestatin prepropeptide 5 0.517 0.769 1.4E-11 0.500 None 0.923 0 2 2001 2019
Entrez Id: 155
Gene Symbol: ADRB3
ADRB3 		P13945 adrenoceptor beta 3 G-protein coupled receptor 9 0.533 0.731 2.5E-07 0.500 None 0.905 0 1 1995 2019
Entrez Id: 154
Gene Symbol: ADRB2
ADRB2 		P07550 adrenoceptor beta 2 G-protein coupled receptor 6 0.442 0.923 0.53 0.500 None 0.884 0 0 1997 2019
Entrez Id: 9607
Gene Symbol: CARTPT
CARTPT 		Q16568 CART prepropeptide 3 0.576 0.692 9.4E-02 0.500 None 0.917 0 1 1999 2017
Entrez Id: 3630
Gene Symbol: INS
INS 		P01308 insulin 82 0.445 0.923 0.30 0.500 None 0.895 0 0 1989 2019
Entrez Id: 348
Gene Symbol: APOE
APOE 		P02649 apolipoprotein E 108 0.338 0.962 1.9E-03 0.500 None 0.974 0 0 1988 2019
Entrez Id: 109
Gene Symbol: ADCY3
ADCY3 		O60266 adenylate cyclase 3 23 0.678 0.615 2.0E-11 0.490 None 1.000 0 0 2008 2018
Entrez Id: 2778
Gene Symbol: GNAS
GNAS 		O95467 P63092 P84996 Q5JWF2 GNAS complex locus Enzyme modulator 232 0.420 0.885 0.68 0.490 None 1.000 0 1 2003 2018
Entrez Id: 4864
Gene Symbol: NPC1
NPC1 		O15118 NPC intracellular cholesterol transporter 1 Transporter 53 0.518 0.692 6.5E-06 0.480 None 1.000 1 1 2009 2018