Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
P01137 transforming growth factor beta 1 Signaling 1558 0.287 0.962 3.7E-02 0.150 None 1.000 6 2 2011 2019
Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3
P84022 SMAD family member 3 Transcription factor 470 0.415 0.923 0.80 0.440 None 1.000 6 4 2010 2019
Entrez Id: 1301
Gene Symbol: COL11A1
COL11A1
P12107 collagen type XI alpha 1 chain 268 0.495 0.846 1.00 0.440 None 1.000 5 6 2014 2019
Entrez Id: 2487
Gene Symbol: FRZB
FRZB
Q92765 frizzled related protein 89 0.573 0.654 1.1E-03 0.140 None 1.000 4 2 2004 2009
Entrez Id: 1311
Gene Symbol: COMP
COMP
P49747 cartilage oligomeric matrix protein 230 0.503 0.808 1.3E-09 0.440 None 1.000 4 0 2014 2019
Entrez Id: 805
Gene Symbol: CALM2
CALM2
P0DP23 P0DP24 P0DP25 calmodulin 2 Calcium-binding protein 252 0.472 0.808 0.92 0.030 None 1.000 3 1 2005 2010
Entrez Id: 1280
Gene Symbol: COL2A1
COL2A1
P02458 collagen type II alpha 1 chain 496 0.444 0.846 1.00 0.130 None 1.000 3 1 2002 2010
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
Q16552 interleukin 17A 1074 0.324 0.923 4.3E-02 0.030 None 1.000 3 1 2017 2019
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
P10145 C-X-C motif chemokine ligand 8 Signaling 1254 0.310 0.962 2.7E-04 0.030 None 1.000 3 0 2014 2018
Entrez Id: 3077
Gene Symbol: HFE
HFE
Q30201 homeostatic iron regulator 415 0.436 0.846 2.6E-08 0.420 None 1.000 3 1 2010 2018
Entrez Id: 3589
Gene Symbol: IL11
IL11
P20809 interleukin 11 244 0.481 0.808 3.2E-04 0.410 None 1.000 2 1 2018 2019
Entrez Id: 27145
Gene Symbol: FILIP1
FILIP1
Q7Z7B0 filamin A interacting protein 1 8 0.861 0.154 2.6E-10 0.400 None 1.000 2 1 2018 2019
Entrez Id: 4054
Gene Symbol: LTBP3
LTBP3
Q9NS15 latent transforming growth factor beta binding protein 3 Calcium-binding protein 150 0.564 0.846 0.69 0.400 None 1.000 2 1 2018 2019
Entrez Id: 4010
Gene Symbol: LMX1B
LMX1B
O60663 LIM homeobox transcription factor 1 beta Nucleic acid binding 132 0.565 0.731 0.75 0.400 None 1.000 2 2 2018 2019
Entrez Id: 3371
Gene Symbol: TNC
TNC
P24821 tenascin C 369 0.433 0.846 1.3E-07 0.400 None 1.000 2 2 2018 2019
Entrez Id: 3697
Gene Symbol: ITIH1
ITIH1
P19827 inter-alpha-trypsin inhibitor heavy chain 1 Enzyme modulator 38 0.691 0.462 2.1E-31 0.400 None 1.000 2 3 2018 2019
Entrez Id: 5608
Gene Symbol: MAP2K6
MAP2K6
P52564 mitogen-activated protein kinase kinase 6 Kinase 59 0.631 0.615 0.91 0.100 None 1.000 2 1 2018 2018
Entrez Id: 4314
Gene Symbol: MMP3
MMP3
P08254 matrix metallopeptidase 3 Enzyme 473 0.408 0.885 5.7E-15 0.020 None 1.000 2 0 2006 2019
Entrez Id: 9508
Gene Symbol: ADAMTS3
ADAMTS3
O15072 ADAM metallopeptidase with thrombospondin type 1 motif 3 Enzyme 116 0.581 0.808 1.0E-10 0.020 None 1.000 2 0 2005 2016
Entrez Id: 860
Gene Symbol: RUNX2
RUNX2
Q13950 RUNX family transcription factor 2 Transcription factor 405 0.437 0.846 0.95 0.400 None 1.000 2 2 2018 2019
Entrez Id: 8464
Gene Symbol: SUPT3H
SUPT3H
O75486 SPT3 homolog, SAGA and STAGA complex component Nucleic acid binding 13 0.839 0.154 3.2E-11 0.100 None 1.000 2 2 2018 2019
Entrez Id: 8200
Gene Symbol: GDF5
GDF5
P43026 growth differentiation factor 5 Signaling 238 0.511 0.692 0.67 0.420 None 1.000 2 1 2007 2014
Entrez Id: 81793
Gene Symbol: TLR10
TLR10
Q9BXR5 toll like receptor 10 71 0.592 0.654 3.5E-09 0.020 None 1.000 2 1 2018 2018
Entrez Id: 808
Gene Symbol: CALM3
CALM3
P0DP23 P0DP24 P0DP25 calmodulin 3 Calcium-binding protein 215 0.485 0.846 0.93 0.020 None 1.000 2 0 2005 2006
Entrez Id: 9734
Gene Symbol: HDAC9
HDAC9
Q9UKV0 histone deacetylase 9 Epigenetic regulator 340 0.439 0.846 1.00 0.400 None 1.000 2 2 2018 2018