Source: BEFREE ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1312
Gene Symbol: COMT
COMT 		P21964 catechol-O-methyltransferase Enzyme 449 0.400 0.923 1.1E-06 0.600 None 0.958 118 10 2003 2020
Entrez Id: 6863
Gene Symbol: TAC1
TAC1 		P20366 tachykinin precursor 1 411 0.424 0.923 0.75 0.600 None 0.960 71 0 1993 2020
Entrez Id: 1268
Gene Symbol: CNR1
CNR1 		P21554 cannabinoid receptor 1 G-protein coupled receptor 287 0.446 0.808 0.51 0.600 None 1.000 24 2 2009 2020
Entrez Id: 8989
Gene Symbol: TRPA1
TRPA1 		O75762 transient receptor potential cation channel subfamily A member 1 Ion channel 139 0.546 0.846 7.2E-35 0.500 None 0.973 72 2 2005 2020
Entrez Id: 7442
Gene Symbol: TRPV1
TRPV1 		Q8NER1 transient receptor potential cation channel subfamily V member 1 Ion channel 381 0.446 0.885 1.0E-16 0.400 None 0.977 173 1 2000 2020
Entrez Id: 7124
Gene Symbol: TNF
TNF 		P01375 tumor necrosis factor Signaling 2475 0.231 0.962 0.80 0.400 None 0.960 97 3 2007 2020
Entrez Id: 5368
Gene Symbol: PNOC
PNOC 		Q13519 prepronociceptin Signaling 67 0.603 0.577 1.5E-02 0.400 None 1.000 27 0 1998 2019
Entrez Id: 2643
Gene Symbol: GCH1
GCH1 		P30793 GTP cyclohydrolase 1 Enzyme 168 0.511 0.846 0.90 0.400 None 0.885 26 0 2007 2019
Entrez Id: 5443
Gene Symbol: POMC
POMC 		P01189 proopiomelanocortin 665 0.356 0.846 1.2E-04 0.400 None 1.000 24 0 1972 2019
Entrez Id: 3827
Gene Symbol: KNG1
KNG1 		P01042 kininogen 1 Enzyme modulator 226 0.481 0.885 3.2E-10 0.400 None 1.000 19 0 1986 2020
Entrez Id: 4986
Gene Symbol: OPRK1
OPRK1 		P41145 opioid receptor kappa 1 G-protein coupled receptor 113 0.555 0.615 4.1E-05 0.400 None 0.944 17 5 1998 2019
Entrez Id: 3060
Gene Symbol: HCRT
HCRT 		O43612 hypocretin neuropeptide precursor 211 0.500 0.808 2.9E-02 0.400 None 1.000 15 0 2005 2019
Entrez Id: 1906
Gene Symbol: EDN1
EDN1 		P05305 endothelin 1 Signaling 518 0.380 0.846 0.46 0.400 None 0.933 13 0 2007 2020
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN 		P18510 interleukin 1 receptor antagonist 600 0.373 0.923 3.1E-02 0.390 None 1.000 9 0 2000 2019
Entrez Id: 1392
Gene Symbol: CRH
CRH 		P06850 corticotropin releasing hormone Signaling 303 0.439 0.808 0.72 0.380 None 1.000 8 0 1997 2019
Entrez Id: 1440
Gene Symbol: CSF3
CSF3 		P09919 colony stimulating factor 3 552 0.377 0.885 0.38 0.380 None 1.000 8 0 1995 2020
Entrez Id: 5179
Gene Symbol: PENK
PENK 		P01210 proenkephalin Signaling 92 0.560 0.808 2.1E-04 0.380 None 1.000 8 0 1998 2017
Entrez Id: 1813
Gene Symbol: DRD2
DRD2 		P14416 dopamine receptor D2 G-protein coupled receptor 331 0.436 0.846 0.75 0.360 None 1.000 6 3 2005 2019
Entrez Id: 7432
Gene Symbol: VIP
VIP 		P01282 vasoactive intestinal peptide Signaling 332 0.437 0.846 4.2E-04 0.360 None 0.857 6 0 1998 2019
Entrez Id: 3350
Gene Symbol: HTR1A
HTR1A 		P08908 5-hydroxytryptamine receptor 1A G-protein coupled receptor 148 0.522 0.846 0.20 0.350 None 1.000 5 1 2003 2018
Entrez Id: 551
Gene Symbol: AVP
AVP 		P01185 arginine vasopressin Signaling 378 0.437 0.846 7.4E-02 0.350 None 1.000 5 0 1984 2019
Entrez Id: 213
Gene Symbol: ALB
ALB 		P02768 albumin Transporter 1089 0.317 0.962 0.64 0.340 None 0.600 4 0 1973 2019
Entrez Id: 3558
Gene Symbol: IL2
IL2 		P60568 interleukin 2 894 0.336 0.885 0.48 0.340 None 1.000 4 0 2002 2018
Entrez Id: 358
Gene Symbol: AQP1
AQP1 		P29972 aquaporin 1 (Colton blood group) Ion channel 226 0.467 0.885 2.6E-07 0.340 None 1.000 4 1 2010 2019
Entrez Id: 5173
Gene Symbol: PDYN
PDYN 		P01213 prodynorphin Signaling 92 0.535 0.577 1.7E-04 0.340 None 1.000 4 0 1998 2019