Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1636
Gene Symbol: ACE
ACE
P12821 angiotensin I converting enzyme Enzyme 1082 0.328 0.923 1.0E-37 0.020 None 1.000 2 0 2015 2018
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1
P28482 mitogen-activated protein kinase 1 Kinase 1059 0.330 0.923 1.00 0.010 None 1.000 1 0 2019 2019
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1018 0.333 0.923 1.1E-03 0.330 None 1.000 3 0 2007 2018
Entrez Id: 3952
Gene Symbol: LEP
LEP
P41159 leptin 931 0.349 0.846 0.46 0.030 None 1.000 3 0 2002 2019
Entrez Id: 115482713
Gene Symbol: H3P10
H3P10
H3 histone pseudogene 10 769 0.350 0.846 0.010 None 1.000 1 0 2009 2009
Entrez Id: 836
Gene Symbol: CASP3
CASP3
P42574 caspase 3 Enzyme 819 0.351 0.923 0.10 0.200 None 1.000 1 0 2006 2006
Entrez Id: 7421
Gene Symbol: VDR
VDR
P11473 vitamin D receptor Nuclear receptor 852 0.352 0.885 1.7E-05 0.010 None 1.000 1 0 2018 2018
Entrez Id: 4513
Gene Symbol: COX2
COX2
P00403 cytochrome c oxidase subunit II Enzyme 875 0.352 0.962 0.100 None 0 0
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
Q16236 nuclear factor, erythroid 2 like 2 Enzyme 823 0.357 0.885 3.6E-03 0.020 None 1.000 2 0 2018 2019
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 877 0.358 0.885 2.9E-02 0.320 None 1.000 3 0 2008 2019
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3
Q96P20 NLR family pyrin domain containing 3 805 0.361 0.962 8.1E-04 0.030 None 1.000 3 0 2017 2020
Entrez Id: 7097
Gene Symbol: TLR2
TLR2
O60603 toll like receptor 2 749 0.361 0.923 1.0E-06 0.200 None 1.000 1 0 2009 2009
Entrez Id: 4193
Gene Symbol: MDM2
MDM2
Q00987 MDM2 proto-oncogene Nucleic acid binding 702 0.362 0.846 1.00 0.200 None 1.000 1 0 2010 2010
Entrez Id: 406991
Gene Symbol: MIR21
MIR21
microRNA 21 726 0.363 0.846 0.020 None 1.000 2 0 2018 2018
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
P05362 intercellular adhesion molecule 1 737 0.364 0.962 3.5E-02 0.220 None 1.000 3 0 2009 2012
Entrez Id: 4843
Gene Symbol: NOS2
NOS2
P35228 nitric oxide synthase 2 783 0.364 0.923 4.0E-15 0.010 None 1.000 1 0 2017 2017
Entrez Id: 3606
Gene Symbol: IL18
IL18
Q14116 interleukin 18 750 0.365 0.923 3.1E-02 0.240 None 1.000 6 0 2007 2019
Entrez Id: 2335
Gene Symbol: FN1
FN1
P02751 fibronectin 1 Signaling 724 0.365 0.962 1.4E-03 0.010 None 1.000 1 0 2012 2012
Entrez Id: 3146
Gene Symbol: HMGB1
HMGB1
P09429 high mobility group box 1 Nucleic acid binding 724 0.368 0.923 0.82 0.050 None 1.000 5 0 2009 2019
Entrez Id: 1493
Gene Symbol: CTLA4
CTLA4
P16410 cytotoxic T-lymphocyte associated protein 4 722 0.369 0.923 0.94 0.130 None 1.000 3 0 2008 2019
Entrez Id: 3439
Gene Symbol: IFNA1
IFNA1
P01562 interferon alpha 1 662 0.371 0.923 0.010 None < 0.001 1 0 2011 2011
Entrez Id: 355
Gene Symbol: FAS
FAS
P25445 Fas cell surface death receptor 754 0.372 0.923 0.81 0.110 None 1.000 1 0 2002 2002
Entrez Id: 3082
Gene Symbol: HGF
HGF
P14210 hepatocyte growth factor Enzyme 671 0.374 0.885 1.00 0.300 None 1.000 1 0 2004 2004
Entrez Id: 3447
Gene Symbol: IFNA13
IFNA13
P01562 interferon alpha 13 646 0.374 0.923 0.010 None < 0.001 1 0 2011 2011
Entrez Id: 4353
Gene Symbol: MPO
MPO
P05164 myeloperoxidase Enzyme 653 0.377 0.923 7.1E-15 0.330 None 1.000 4 0 2006 2019