Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 211
Gene Symbol: ALAS1
ALAS1 		P13196 5'-aminolevulinate synthase 1 Enzyme 27 0.705 0.462 0.11 0.520 None 1.000 4 0 1995 2019
Entrez Id: 7389
Gene Symbol: UROD
UROD 		P06132 uroporphyrinogen decarboxylase 166 0.521 0.769 1.3E-08 0.100 None 1.000 17 1 1986 2019
Entrez Id: 3145
Gene Symbol: HMBS
HMBS 		P08397 hydroxymethylbilane synthase Enzyme 140 0.559 0.731 0.95 0.080 None 1.000 8 2 1978 2013
Entrez Id: 210
Gene Symbol: ALAD
ALAD 		P13716 aminolevulinate dehydratase Enzyme 135 0.556 0.615 5.6E-05 0.080 None 1.000 8 0 1981 2014
Entrez Id: 5498
Gene Symbol: PPOX
PPOX 		P50336 protoporphyrinogen oxidase 53 0.678 0.500 2.8E-02 0.050 None 1.000 5 1 1997 2011
Entrez Id: 1371
Gene Symbol: CPOX
CPOX 		P36551 coproporphyrinogen oxidase Enzyme 246 0.488 0.846 0.17 0.040 None 1.000 4 0 1995 2011
Entrez Id: 2235
Gene Symbol: FECH
FECH 		P22830 ferrochelatase Enzyme 88 0.585 0.577 2.8E-03 0.040 None 1.000 4 0 1982 2016
Entrez Id: 3077
Gene Symbol: HFE
HFE 		Q30201 homeostatic iron regulator 415 0.436 0.846 2.6E-08 0.030 None 1.000 3 2 1999 2019
Entrez Id: 7390
Gene Symbol: UROS
UROS 		P10746 uroporphyrinogen III synthase Enzyme 58 0.678 0.462 3.2E-02 0.020 None 1.000 2 1 2016 2019
Entrez Id: 4000
Gene Symbol: LMNA
LMNA 		P02545 lamin A/C 824 0.384 0.885 1.00 0.020 None 1.000 2 0 2013 2017
Entrez Id: 212
Gene Symbol: ALAS2
ALAS2 		P22557 5'-aminolevulinate synthase 2 Enzyme 79 0.606 0.577 1.00 0.020 None 0.500 2 0 2019 2019
Entrez Id: 796
Gene Symbol: CALCA
CALCA 		P01258 P06881 calcitonin related polypeptide alpha Signaling 467 0.416 0.923 1.6E-02 0.020 None 1.000 2 0 1989 1989
Entrez Id: 10058
Gene Symbol: ABCB6
ABCB6 		Q9NP58 ATP binding cassette subfamily B member 6 (Langereis blood group) Transporter 400 0.431 0.885 8.6E-19 0.020 None 1.000 2 0 2016 2017
Entrez Id: 4068
Gene Symbol: SH2D1A
SH2D1A 		O60880 SH2 domain containing 1A 160 0.525 0.731 0.39 0.010 None 1.000 1 0 2015 2015
Entrez Id: 57817
Gene Symbol: HAMP
HAMP 		P81172 hepcidin antimicrobial peptide 377 0.433 0.846 8.2E-03 0.010 None 1.000 1 0 2008 2008
Entrez Id: 6565
Gene Symbol: SLC15A2
SLC15A2 		Q16348 solute carrier family 15 member 2 Transporter 13 0.805 0.308 5.5E-20 0.010 None 1.000 1 0 2017 2017
Entrez Id: 3875
Gene Symbol: KRT18
KRT18 		P05783 keratin 18 151 0.530 0.692 0.73 0.010 None 1.000 1 0 2019 2019
Entrez Id: 2632
Gene Symbol: GBE1
GBE1 		Q04446 1,4-alpha-glucan branching enzyme 1 Enzyme 102 0.612 0.654 1.1E-12 0.010 None 1.000 1 0 2019 2019
Entrez Id: 2623
Gene Symbol: GATA1
GATA1 		P15976 GATA binding protein 1 264 0.483 0.808 0.95 0.010 None 1.000 1 0 2007 2007
Entrez Id: 2056
Gene Symbol: EPO
EPO 		P01588 erythropoietin 646 0.381 0.885 1.1E-02 0.010 None 1.000 1 0 2002 2002
Entrez Id: 1576
Gene Symbol: CYP3A4
CYP3A4 		P08684 cytochrome P450 family 3 subfamily A member 4 Enzyme 291 0.462 0.885 5.8E-11 0.010 None 1.000 1 0 2002 2002
Entrez Id: 1565
Gene Symbol: CYP2D6
CYP2D6 		P10635 cytochrome P450 family 2 subfamily D member 6 432 0.437 0.885 1.1E-25 0.010 None 1.000 1 0 2007 2007
Entrez Id: 1555
Gene Symbol: CYP2B6
CYP2B6 		P20813 cytochrome P450 family 2 subfamily B member 6 388 0.428 0.846 1.9E-10 0.010 None 1.000 1 0 2002 2002
Entrez Id: 1401
Gene Symbol: CRP
CRP 		P02741 C-reactive protein 1483 0.299 0.962 3.7E-03 0.010 None 1.000 1 0 2002 2002
Entrez Id: 10891
Gene Symbol: PPARGC1A
PPARGC1A 		Q9UBK2 PPARG coactivator 1 alpha Transcription factor 350 0.453 0.885 1.00 0.010 None 1.000 1 0 2005 2005