Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7389
Gene Symbol: UROD
UROD
P06132 uroporphyrinogen decarboxylase 166 0.521 0.769 1.3E-08 0.100 None 0.857 14 0 2013 2019
Entrez Id: 4615
Gene Symbol: MYD88
MYD88
Q99836 MYD88 innate immune signal transduction adaptor Enzyme modulator 480 0.414 0.923 0.12 0.100 None 1.000 13 0 2009 2019
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
Q16236 nuclear factor, erythroid 2 like 2 Enzyme 823 0.357 0.885 3.6E-03 0.100 None 1.000 13 0 2007 2019
Entrez Id: 834
Gene Symbol: CASP1
CASP1
P29466 caspase 1 Enzyme 444 0.413 0.885 3.5E-05 0.100 None 1.000 13 0 2006 2019
Entrez Id: 11093
Gene Symbol: ADAMTS13
ADAMTS13
Q76LX8 ADAM metallopeptidase with thrombospondin type 1 motif 13 Enzyme 229 0.496 0.769 5.1E-15 0.100 None 1.000 12 0 2006 2020
Entrez Id: 255738
Gene Symbol: PCSK9
PCSK9
Q8NBP7 proprotein convertase subtilisin/kexin type 9 Enzyme 257 0.482 0.808 2.7E-17 0.100 None 0.917 12 0 2017 2019
Entrez Id: 284
Gene Symbol: ANGPT1
ANGPT1
Q15389 angiopoietin 1 Signaling 340 0.446 0.808 0.95 0.400 None 1.000 11 0 2005 2019
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 1044 0.327 0.923 0.98 0.100 None 0.909 11 0 2011 2019
Entrez Id: 3934
Gene Symbol: LCN2
LCN2
P80188 lipocalin 2 Enzyme 497 0.405 0.885 1.1E-09 0.100 None 1.000 11 0 2014 2019
Entrez Id: 836
Gene Symbol: CASP3
CASP3
P42574 caspase 3 Enzyme 819 0.351 0.923 0.10 0.400 None 1.000 11 0 2005 2020
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
P18510 interleukin 1 receptor antagonist 701 0.373 0.923 3.1E-02 0.100 None 0.900 10 0 1999 2019
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD
O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1119 0.319 0.885 1.00 0.100 None 1.000 10 0 2011 2019
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1101 0.320 0.885 1.4E-06 0.100 None 1.000 10 0 2011 2019
Entrez Id: 5806
Gene Symbol: PTX3
PTX3
P26022 pentraxin 3 296 0.457 0.808 7.0E-05 0.100 None 1.000 10 0 2001 2019
Entrez Id: 90865
Gene Symbol: IL33
IL33
O95760 interleukin 33 487 0.409 0.885 8.3E-10 0.100 None 1.000 10 0 2017 2019
Entrez Id: 1153
Gene Symbol: CIRBP
CIRBP
Q14011 cold inducible RNA binding protein Nucleic acid binding 72 0.592 0.731 0.34 0.090 None 1.000 9 0 2013 2019
Entrez Id: 2875
Gene Symbol: GPT
GPT
P24298 glutamic--pyruvic transaminase Enzyme 511 0.403 0.923 3.6E-19 0.090 None 1.000 9 0 2017 2019
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
P05362 intercellular adhesion molecule 1 737 0.364 0.962 3.5E-02 0.090 None 1.000 9 0 2005 2019
Entrez Id: 3684
Gene Symbol: ITGAM
ITGAM
P11215 integrin subunit alpha M 343 0.443 0.808 3.3E-11 0.090 None 1.000 9 0 2001 2019
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1511 0.292 0.923 1.00 0.090 None 1.000 9 0 2011 2019
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB
P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1083 0.322 0.885 1.00 0.090 None 1.000 9 0 2011 2019
Entrez Id: 60
Gene Symbol: ACTB
ACTB
P60709 actin beta Cellular structure 1110 0.325 0.923 0.99 0.090 None 0.889 9 0 2006 2018
Entrez Id: 728
Gene Symbol: C5AR1
C5AR1
P21730 complement C5a receptor 1 G-protein coupled receptor 179 0.513 0.808 0.40 0.090 None 1.000 9 0 2001 2019
Entrez Id: 7450
Gene Symbol: VWF
VWF
P04275 von Willebrand factor Enzyme modulator 498 0.408 0.885 3.2E-25 0.090 None 1.000 9 0 2010 2020
Entrez Id: 79792
Gene Symbol: GSDMD
GSDMD
P57764 gasdermin D 50 0.641 0.692 1.1E-13 0.090 None 1.000 9 0 2017 2020