Source: BEFREE ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7124
Gene Symbol: TNF
TNF 		P01375 tumor necrosis factor Signaling 2475 0.231 0.962 0.80 0.400 None 0.981 159 2 1995 2020
Entrez Id: 7099
Gene Symbol: TLR4
TLR4 		O00206 toll like receptor 4 1030 0.321 0.962 4.6E-09 0.400 None 0.967 90 3 2001 2020
Entrez Id: 3146
Gene Symbol: HMGB1
HMGB1 		P09429 high mobility group box 1 Nucleic acid binding 671 0.368 0.923 0.82 0.400 None 0.956 88 3 2004 2020
Entrez Id: 3586
Gene Symbol: IL10
IL10 		P22301 interleukin 10 1533 0.281 0.923 5.9E-03 0.400 None 0.974 76 3 2000 2019
Entrez Id: 133
Gene Symbol: ADM
ADM 		P35318 adrenomedullin Signaling 354 0.436 0.808 4.1E-02 0.400 None 1.000 22 0 2000 2020
Entrez Id: 3458
Gene Symbol: IFNG
IFNG 		P01579 interferon gamma 1361 0.288 0.962 0.47 0.400 None 1.000 20 0 1998 2019
Entrez Id: 5624
Gene Symbol: PROC
PROC 		P04070 protein C, inactivator of coagulation factors Va and VIIIa Enzyme 165 0.504 0.808 1.9E-05 0.400 None 1.000 19 0 2000 2019
Entrez Id: 1440
Gene Symbol: CSF3
CSF3 		P09919 colony stimulating factor 3 552 0.377 0.885 0.38 0.400 None 1.000 14 0 2000 2020
Entrez Id: 284
Gene Symbol: ANGPT1
ANGPT1 		Q15389 angiopoietin 1 Signaling 317 0.446 0.808 0.95 0.400 None 1.000 10 0 2005 2019
Entrez Id: 4843
Gene Symbol: NOS2
NOS2 		P35228 nitric oxide synthase 2 572 0.364 0.923 4.0E-15 0.400 None 1.000 10 1 2003 2019
Entrez Id: 836
Gene Symbol: CASP3
CASP3 		P42574 caspase 3 Enzyme 722 0.351 0.923 0.10 0.400 None 1.000 10 0 2005 2020
Entrez Id: 4049
Gene Symbol: LTA
LTA 		P01374 lymphotoxin alpha Signaling 329 0.434 0.885 0.20 0.390 None 1.000 9 1 1999 2016
Entrez Id: 3929
Gene Symbol: LBP
LBP 		P18428 lipopolysaccharide binding protein 141 0.525 0.808 4.2E-15 0.380 None 0.875 8 2 1993 2018
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1 		P28482 mitogen-activated protein kinase 1 Kinase 935 0.330 0.923 1.00 0.350 None 1.000 5 0 2004 2019
Entrez Id: 4318
Gene Symbol: MMP9
MMP9 		P14780 matrix metallopeptidase 9 Enzyme 1160 0.305 0.923 1.9E-17 0.330 None 1.000 3 0 2001 2018
Entrez Id: 4846
Gene Symbol: NOS3
NOS3 		P29474 nitric oxide synthase 3 559 0.378 0.885 6.7E-07 0.330 None 0.500 3 1 2009 2018
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1 		P01137 transforming growth factor beta 1 Signaling 1334 0.287 0.962 3.7E-02 0.330 None 1.000 3 0 2005 2018
Entrez Id: 7045
Gene Symbol: TGFBI
TGFBI 		Q15582 transforming growth factor beta induced Signaling 200 0.484 0.769 6.0E-08 0.330 None 1.000 3 0 2017 2020
Entrez Id: 3579
Gene Symbol: CXCR2
CXCR2 		P25025 C-X-C motif chemokine receptor 2 G-protein coupled receptor 300 0.445 0.923 1.4E-02 0.320 None 0.667 2 0 2007 2020
Entrez Id: 4282
Gene Symbol: MIF
MIF 		P14174 macrophage migration inhibitory factor 374 0.412 0.885 1.2E-02 0.320 None 1.000 2 0 1999 2018
Entrez Id: 3569
Gene Symbol: IL6
IL6 		P05231 interleukin 6 2132 0.248 0.962 0.32 0.100 None 0.934 151 3 1991 2020
Entrez Id: 1401
Gene Symbol: CRP
CRP 		P02741 C-reactive protein 1410 0.299 0.962 3.7E-03 0.100 None 0.956 114 2 1999 2020
Entrez Id: 3553
Gene Symbol: IL1B
IL1B 		P01584 interleukin 1 beta 1604 0.276 0.962 0.13 0.100 None 0.984 62 4 1993 2020
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3 		Q96P20 NLR family pyrin domain containing 3 702 0.361 0.962 8.1E-04 0.100 None 1.000 31 2 2013 2020
Entrez Id: 213
Gene Symbol: ALB
ALB 		P02768 albumin Transporter 1089 0.317 0.962 0.64 0.100 None 0.903 31 0 2006 2019