Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1636
Gene Symbol: ACE
ACE
P12821 angiotensin I converting enzyme Enzyme 101 0.328 0.923 1.0E-37 0.600 None 0.844 1 0 1994 2020
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 340 0.231 0.962 0.80 0.600 None 0.956 1 0 1999 2020
Entrez Id: 3690
Gene Symbol: ITGB3
ITGB3
P05106 integrin subunit beta 3 Receptor 28 0.485 0.846 1.7E-03 0.590 None 1.000 1 0 1998 2019
Entrez Id: 3674
Gene Symbol: ITGA2B
ITGA2B
P08514 integrin subunit alpha 2b 20 0.493 0.692 1.5E-16 0.570 None 0.667 1 0 1997 2017
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
P05362 intercellular adhesion molecule 1 57 0.364 0.962 3.5E-02 0.570 None 0.889 1 0 1999 2019
Entrez Id: 4843
Gene Symbol: NOS2
NOS2
P35228 nitric oxide synthase 2 184 0.364 0.923 4.0E-15 0.560 None 1.000 1 0 1999 2018
Entrez Id: 1909
Gene Symbol: EDNRA
EDNRA
P25101 endothelin receptor type A G-protein coupled receptor 28 0.426 0.885 0.99 0.510 None 1.000 1 0 2007 2019
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
P42898 methylenetetrahydrofolate reductase 192 0.337 0.885 3.2E-10 0.500 None 0.938 3 0 1997 2019
Entrez Id: 2147
Gene Symbol: F2
F2
P00734 coagulation factor II, thrombin Enzyme 61 0.415 0.885 1.1E-03 0.500 None 0.946 1 1 1995 2020
Entrez Id: 4018
Gene Symbol: LPA
LPA
P08519 lipoprotein(a) Enzyme 15 0.444 0.769 6.6E-89 0.500 None 1.000 1 1 1989 2019
Entrez Id: 2153
Gene Symbol: F5
F5
P12259 coagulation factor V Enzyme 44 0.441 0.846 5.9E-15 0.500 None 0.971 1 1 1995 2016
Entrez Id: 9734
Gene Symbol: HDAC9
HDAC9
Q9UKV0 histone deacetylase 9 Epigenetic regulator 7 0.439 0.846 1.00 0.500 None 1.000 1 2 2012 2019
Entrez Id: 1282
Gene Symbol: COL4A1
COL4A1
P02462 collagen type IV alpha 1 chain 51 0.484 0.731 1.00 0.500 strong 1.000 1 1 2006 2020
Entrez Id: 4854
Gene Symbol: NOTCH3
NOTCH3
Q9UM47 notch receptor 3 31 0.435 0.808 0.41 0.500 strong 0.973 1 2 1996 2020
Entrez Id: 1471
Gene Symbol: CST3
CST3
P01034 cystatin C 55 0.436 0.808 3.9E-03 0.500 limited 1.000 0 0 1989 2020
Entrez Id: 351
Gene Symbol: APP
APP
P05067 amyloid beta precursor protein Enzyme modulator 76 0.422 0.846 4.7E-02 0.490 strong 1.000 1 0 2002 2014
Entrez Id: 463
Gene Symbol: ZFHX3
ZFHX3
Q15911 Q6ZP98 zinc finger homeobox 3 9 0.621 0.654 0.45 0.480 None 1.000 1 3 2012 2019
Entrez Id: 54897
Gene Symbol: CASZ1
CASZ1
Q86V15 castor zinc finger 1 Transcription factor 8 0.553 0.731 1.00 0.440 None 1.000 1 1 2017 2018
Entrez Id: 28
Gene Symbol: ABO
ABO
P16442 ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase Enzyme 16 0.427 0.885 0.430 None 1.000 1 1 2009 2018
Entrez Id: 10019
Gene Symbol: SH2B3
SH2B3
Q9UQQ2 SH2B adaptor protein 3 26 0.527 0.692 1.0E-04 0.410 None 1.000 1 1 2012 2018
Entrez Id: 5327
Gene Symbol: PLAT
PLAT
P00750 plasminogen activator, tissue type Enzyme 136 0.445 0.885 5.7E-05 0.400 None 0.973 58 0 1989 2020
Entrez Id: 213
Gene Symbol: ALB
ALB
P02768 albumin Transporter 123 0.317 0.962 0.64 0.400 None 0.958 4 0 1998 2020
Entrez Id: 2717
Gene Symbol: GLA
GLA
P06280 galactosidase alpha 15 0.537 0.769 1.00 0.400 strong 1.000 1 0 2004 2018
Entrez Id: 5139
Gene Symbol: PDE3A
PDE3A
Q14432 phosphodiesterase 3A 6 0.670 0.577 1.9E-04 0.400 None 1.000 1 1 2018 2018
Entrez Id: 3777
Gene Symbol: KCNK3
KCNK3
O14649 potassium two pore domain channel subfamily K member 3 Ion channel 16 0.584 0.654 0.90 0.400 None 1.000 1 1 2018 2018