Source: BEFREE ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		P42898 methylenetetrahydrofolate reductase 816 0.337 0.885 3.2E-10 0.500 None 0.962 24 4 1995 2017
Entrez Id: 5077
Gene Symbol: PAX3
PAX3 		P23760 paired box 3 154 0.481 0.769 0.24 0.480 None 0.909 8 1 1984 2017
Entrez Id: 5156
Gene Symbol: PDGFRA
PDGFRA 		P16234 platelet derived growth factor receptor alpha Kinase 383 0.415 0.808 1.00 0.350 None 1.000 5 0 1998 2011
Entrez Id: 57216
Gene Symbol: VANGL2
VANGL2 		Q9ULK5 VANGL planar cell polarity protein 2 52 0.588 0.615 0.84 0.330 None 1.000 3 0 2011 2018
Entrez Id: 5110
Gene Symbol: PCMT1
PCMT1 		P22061 protein-L-isoaspartate (D-aspartate) O-methyltransferase Enzyme 25 0.691 0.423 0.78 0.320 None 1.000 2 2 2006 2012
Entrez Id: 5444
Gene Symbol: PON1
PON1 		P27169 paraoxonase 1 387 0.409 0.885 9.8E-11 0.310 None 1.000 1 2 2010 2010
Entrez Id: 6347
Gene Symbol: CCL2
CCL2 		P13500 C-C motif chemokine ligand 2 Signaling 994 0.321 0.962 0.61 0.310 None 1.000 1 0 2006 2008
Entrez Id: 5130
Gene Symbol: PCYT1A
PCYT1A 		P49585 phosphate cytidylyltransferase 1, choline, alpha 186 0.485 0.885 2.0E-05 0.310 None 1.000 1 1 2006 2006
Entrez Id: 1119
Gene Symbol: CHKA
CHKA 		P35790 choline kinase alpha Kinase 61 0.615 0.615 0.23 0.310 None 1.000 1 0 2006 2006
Entrez Id: 1072
Gene Symbol: CFL1
CFL1 		P23528 cofilin 1 128 0.529 0.769 0.56 0.310 None 1.000 1 3 2007 2007
Entrez Id: 25828
Gene Symbol: TXN2
TXN2 		Q99757 thioredoxin 2 Enzyme 35 0.628 0.615 2.6E-05 0.310 None 1.000 1 0 2009 2009
Entrez Id: 4552
Gene Symbol: MTRR
MTRR 		Q9UBK8 5-methyltetrahydrofolate-homocysteine methyltransferase reductase 159 0.502 0.808 2.2E-14 0.180 None 1.000 7 4 1999 2017
Entrez Id: 4548
Gene Symbol: MTR
MTR 		Q99707 5-methyltetrahydrofolate-homocysteine methyltransferase 196 0.482 0.808 2.4E-12 0.150 None 0.800 4 0 1997 2009
Entrez Id: 4522
Gene Symbol: MTHFD1
MTHFD1 		P11586 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 Enzyme 90 0.554 0.769 4.5E-03 0.120 None 1.000 2 3 2009 2016
Entrez Id: 5727
Gene Symbol: PTCH1
PTCH1 		Q13635 patched 1 339 0.398 0.885 1.00 0.110 None 1.000 1 2 2013 2013
Entrez Id: 6576
Gene Symbol: SLC25A1
SLC25A1 		P53007 solute carrier family 25 member 1 Transporter 72 0.553 0.731 5.9E-02 0.110 None 1.000 1 0 2006 2006
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1 		P38398 BRCA1 DNA repair associated Enzyme 576 0.367 0.923 9.2E-29 0.110 None 1.000 1 0 2007 2007
Entrez Id: 1719
Gene Symbol: DHFR
DHFR 		P00374 dihydrofolate reductase Enzyme 153 0.513 0.808 3.4E-02 0.040 None 0.750 4 0 2004 2009
Entrez Id: 57822
Gene Symbol: GRHL3
GRHL3 		Q8TE85 grainyhead like transcription factor 3 Transcription factor 70 0.572 0.692 0.99 0.040 None 1.000 4 1 2017 2019
Entrez Id: 7546
Gene Symbol: ZIC2
ZIC2 		O95409 Zic family member 2 Transcription factor 67 0.556 0.769 0.97 0.040 None 1.000 4 0 2000 2018
Entrez Id: 80199
Gene Symbol: FUZ
FUZ 		Q9BT04 fuzzy planar cell polarity protein 26 0.597 0.731 1.3E-05 0.040 None 1.000 4 0 1989 2012
Entrez Id: 9620
Gene Symbol: CELSR1
CELSR1 		Q9NYQ6 cadherin EGF LAG seven-pass G-type receptor 1 G-protein coupled receptor 23 0.700 0.500 1.00 0.030 None 1.000 3 0 2014 2018
Entrez Id: 9
Gene Symbol: NAT1
NAT1 		P18440 N-acetyltransferase 1 Enzyme 122 0.536 0.846 1.9E-14 0.030 None 0.667 3 0 2005 2007
Entrez Id: 875
Gene Symbol: CBS
CBS 		P0DN79 P35520 cystathionine beta-synthase Enzyme 212 0.465 0.885 3.1E-05 0.030 None 1.000 3 3 2000 2009
Entrez Id: 7298
Gene Symbol: TYMS
TYMS 		P04818 thymidylate synthetase Enzyme 356 0.425 0.846 0.72 0.030 None 1.000 3 3 2003 2009