Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1636
Gene Symbol: ACE
ACE
P12821 angiotensin I converting enzyme Enzyme 1082 0.328 0.923 1.0E-37 0.010 None 1.000 1 1 2016 2016
Entrez Id: 9429
Gene Symbol: ABCG2
ABCG2
Q9UNQ0 ATP binding cassette subfamily G member 2 (Junior blood group) Transporter 420 0.419 0.885 2.1E-32 0.010 None 1.000 1 0 2009 2009
Entrez Id: 3949
Gene Symbol: LDLR
LDLR
P01130 low density lipoprotein receptor 336 0.449 0.885 9.8E-24 0.010 None 1.000 1 0 2006 2006
Entrez Id: 3339
Gene Symbol: HSPG2
HSPG2
P98160 heparan sulfate proteoglycan 2 Enzyme modulator 405 0.438 0.885 1.0E-19 0.010 None 1.000 1 0 1995 1995
Entrez Id: 4311
Gene Symbol: MME
MME
P08473 membrane metalloendopeptidase Enzyme 470 0.407 0.808 1.5E-18 0.070 None 1.000 7 0 2002 2017
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
P14780 matrix metallopeptidase 9 Enzyme 1337 0.305 0.923 1.9E-17 0.010 None 1.000 1 0 2015 2015
Entrez Id: 51112
Gene Symbol: TRAPPC12
TRAPPC12
Q8WVT3 trafficking protein particle complex 12 Enzyme 28 0.751 0.385 5.4E-16 0.100 None 1.000 1 1 2018 2018
Entrez Id: 3687
Gene Symbol: ITGAX
ITGAX
P20702 integrin subunit alpha X 170 0.504 0.769 1.4E-15 0.010 None 1.000 1 0 1997 1997
Entrez Id: 314
Gene Symbol: AOC2
AOC2
O75106 amine oxidase copper containing 2 37 0.674 0.654 3.3E-15 0.010 None 1.000 1 0 2015 2015
Entrez Id: 1284
Gene Symbol: COL4A2
COL4A2
P08572 collagen type IV alpha 2 chain 131 0.563 0.654 3.6E-15 0.020 None 1.000 2 0 2019 2019
Entrez Id: 12
Gene Symbol: SERPINA3
SERPINA3
P01011 serpin family A member 3 Enzyme modulator 229 0.486 0.846 8.8E-14 0.010 None 1.000 1 0 2000 2000
Entrez Id: 590
Gene Symbol: BCHE
BCHE
P06276 butyrylcholinesterase 392 0.447 0.923 1.1E-13 0.010 None 1.000 1 0 1998 1998
Entrez Id: 19
Gene Symbol: ABCA1
ABCA1
O95477 ATP binding cassette subfamily A member 1 Transporter 291 0.467 0.846 1.5E-13 0.020 None 1.000 2 1 2005 2012
Entrez Id: 3918
Gene Symbol: LAMC2
LAMC2
Q13753 laminin subunit gamma 2 Enzyme modulator 602 0.389 0.923 2.9E-12 0.020 None 1.000 2 0 2017 2018
Entrez Id: 51129
Gene Symbol: ANGPTL4
ANGPTL4
Q9BY76 angiopoietin like 4 Signaling 198 0.498 0.731 2.3E-11 0.010 None 1.000 1 0 2018 2018
Entrez Id: 2
Gene Symbol: A2M
A2M
P01023 alpha-2-macroglobulin Enzyme modulator 147 0.529 0.769 4.5E-11 0.010 None 1.000 1 0 1999 1999
Entrez Id: 8639
Gene Symbol: AOC3
AOC3
Q16853 amine oxidase copper containing 3 106 0.561 0.769 6.3E-11 0.010 None 1.000 1 0 2015 2015
Entrez Id: 6653
Gene Symbol: SORL1
SORL1
Q92673 sortilin related receptor 1 Transporter 103 0.582 0.692 7.7E-11 0.010 None 1.000 1 0 2019 2019
Entrez Id: 183
Gene Symbol: AGT
AGT
P01019 angiotensinogen Enzyme modulator 765 0.367 0.923 5.0E-08 0.010 None 1.000 1 0 2017 2017
Entrez Id: 960
Gene Symbol: CD44
CD44
P16070 CD44 molecule (Indian blood group) 711 0.363 0.962 2.4E-07 0.010 None 1.000 1 0 1995 1995
Entrez Id: 968
Gene Symbol: CD68
CD68
P34810 CD68 molecule Transporter 452 0.408 0.808 1.4E-06 0.010 None 1.000 1 0 1997 1997
Entrez Id: 780
Gene Symbol: DDR1
DDR1
Q08345 discoidin domain receptor tyrosine kinase 1 Kinase 195 0.497 0.808 4.6E-06 0.010 None 1.000 1 0 2011 2011
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
P08183 ATP binding cassette subfamily B member 1 Transporter 933 0.344 0.885 1.3E-05 0.030 None 1.000 3 0 2004 2017
Entrez Id: 1191
Gene Symbol: CLU
CLU
P10909 clusterin 412 0.426 0.885 7.8E-05 0.030 None 1.000 3 0 2017 2019
Entrez Id: 3552
Gene Symbol: IL1A
IL1A
P01583 interleukin 1 alpha 1002 0.333 0.962 1.6E-04 0.010 None 1.000 1 0 2003 2003